Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionIngalls & Snyder Llc
Latest Disclosed Ownership3,012 shares
Latest Disclosed Value $ 1,345
Ingalls & Snyder Llc reports 6.66% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 13, 2026 - Ingalls & Snyder Llc filed a 13F-HR form disclosing ownership of 3,012 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $1,344,978 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 3,227 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -6.66% during the quarter. The current value of the position is $1,330,521 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-13 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,012 -215 -6.66 1 0.00 0.0476
2026-02-13 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,227 12 0.37 1 0.00 0.0537
2025-11-07 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,215 -69 -2.10 1 0.00 0.0412
2025-07-31 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,284 -40 -1.20 1 0.00 0.0519
2025-05-12 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,324 334 11.17 2 0.00 0.0530
2025-01-29 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,990 2,000 202.02 1 0.0472
2024-11-14 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 990 63 6.80 0 0.0180
2024-07-31 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 927 -106 -10.26 0 0.0187
2024-05-13 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,033 0 0.00 0 0.0191
2024-01-29 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,033 29 2.89 0 0.0190
2023-11-02 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,004 0 0.00 0 0.0168
2023-07-27 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,004 0 0.00 0 0.0169
2023-05-09 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,004 0 0.00 0 0.0162
2023-01-31 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,004 0 0.00 0 -100.00 0.0158
2022-10-21 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,004 0 0.00 291 2.83 0.0162
2022-08-11 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,004 -7 -0.69 283 7.20 0.0148
2022-05-09 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,011 4 0.40 264 19.46 0.0118
2022-02-11 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,007 1,007 221 0.0100
2021-10-27 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -1,007 -100.00 0 -100.00
2021-08-03 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,007 -193 -16.08 203 -21.32 0.0090
2021-04-21 2021-03-31 13F VERTEX PHARMACEUTICALS CO 92532F100 1,200 0 0.00 258 -9.15 0.0120
2021-01-27 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,200 0 0.00 284 -13.15 0.0140
2020-10-21 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,200 0 0.00 327 -6.03 0.0224
2020-07-31 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,200 -2,450 -67.12 348 -59.95 0.0200
2020-04-22 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,650 2,450 204.17 869 230.42 0.0586
2020-01-15 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,200 0 0.00 263 29.56 0.0142
2019-10-16 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,200 0 0.00 203 -7.73 0.0099
2019-07-11 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,200 0 0.00 220 -0.45 0.0106
2019-04-11 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,200 1,200 221 0.0105
2019-01-24 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -1,200 -100.00 0 -100.00
2018-10-24 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,200 0 0.00 231 13.24 0.0097
2018-08-10 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,200 1,200 204 0.0095
2018-01-19 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -3,270 -100.00 0 -100.00
2017-10-20 2017-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,270 0 0.00 497 18.05 0.0259
2017-07-28 2017-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,270 800 32.39 421 55.93 0.0229
2017-05-09 2017-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,470 2,470 270 0.0144
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.