Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionHarding Loevner Lp
Latest Disclosed Ownership313,546 shares
Latest Disclosed Value $ 140,009,344
Harding Loevner Lp reports 19.99% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 15, 2026 - Harding Loevner Lp filed a 13F-HR form disclosing ownership of 313,546 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $140,010,831 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 391,865 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -19.99% during the quarter. The current value of the position is $134,304,294 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 313,546 -78,319 -19.99 140,009 -21.19 1.4405
2026-02-17 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 391,865 -64,123 -14.06 177,661 -0.52 1.5632
2025-11-14 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 455,988 -255,623 -35.92 178,598 -43.63 1.3101
2025-08-14 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 711,611 13,152 1.88 316,824 -6.44 2.1315
2025-05-15 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 698,459 -125,168 -15.20 338,633 2.10 2.5931
2025-02-14 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 823,627 -328,998 -28.54 331,675 -38.13 2.2411
2024-11-14 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,152,625 -31,783 -2.68 536,081 -3.44 3.0925
2024-08-14 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,184,408 -38,630 -3.16 555,173 8.59 3.0641
2024-05-15 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,223,038 -98,191 -7.43 511,234 -5.07 3.1555
2024-02-14 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,321,229 -25,522 -1.90 538,552 15.00 3.0211
2023-11-14 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,346,751 -191,519 -12.45 468,319 -13.49 3.0925
2023-08-14 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,538,270 -288,354 -15.79 541,333 -5.94 3.1604
2023-05-15 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,826,624 -13,897 -0.76 575,531 8.28 3.2761
2023-02-14 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,840,521 200,704 12.24 531,515 11.95 3.0625
2022-11-14 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,639,817 -93,874 -5.41 474,793 -2.81 3.1128
2022-08-15 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,733,691 -35,585 -2.01 488,540 17.06 3.0140
2022-05-16 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,769,276 -112,595 -5.98 417,339 0.99 2.2981
2022-02-14 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,881,871 -29,232 -1.53 413,258 19.21 1.5846
2021-11-15 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,911,103 -87,975 -4.40 346,655 -14.00 1.3832
2021-08-16 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,999,078 15,989 0.81 403,074 -5.41 1.5161
2021-05-17 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,983,089 -60,006 -2.94 426,146 -11.75 1.6675
2021-02-16 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,043,095 42,554 2.13 482,864 -11.30 1.9979
2020-11-16 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,000,541 -21,226 -1.05 544,387 -7.25 1.9637
2020-08-14 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,021,767 -25,507 -1.25 586,939 20.48 2.8097
2020-05-15 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,047,274 -44,382 -2.12 487,149 6.37 2.7181
2020-02-14 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,091,656 -231,426 -9.96 457,968 16.36 2.0366
2019-11-14 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,323,082 1,582,711 213.77 393,576 189.89 1.8555
2019-08-14 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 740,371 -11,673 -1.55 135,769 -1.86 0.6235
2019-05-15 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 752,044 751,975 1,089,818.84 138,338 1,257,518.18 0.6499
2019-02-14 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 69 69 11 0.0001
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.