Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionGuidance Capital, Inc
Latest Disclosed Ownership1,907 shares
Latest Disclosed Value $ 809,255
Guidance Capital, Inc reports 6.12% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 8, 2026 - Guidance Capital, Inc filed a 13F-HR form disclosing ownership of 1,907 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $851,552 USD as of March 31, 2026. The entity filed a previous 13F-HR on January 23, 2026 disclosing 1,797 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 6.12% during the quarter. The current value of the position is $852,105 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-08 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,907 110 6.12 809 -3.58 0.1815
2026-01-23 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,797 167 10.25 840 22.30 0.2052
2025-11-07 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,630 -313 -16.11 687 -23.52 0.1793
2025-08-07 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,943 -332 -14.59 898 -21.32 0.2561
2025-05-06 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,275 174 8.28 1,140 23.51 0.3482
2025-01-27 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,101 395 23.15 924 12.15 0.2826
2024-10-22 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,706 150 9.64 824 6.74 0.2578
2024-08-01 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,556 149 10.59 771 37.92 0.2527
2024-04-17 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,407 24 1.74 559 -1.58 0.2058
2024-03-01 2023-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 1,383 312 29.13 568 53.93 0.2258
2024-01-31 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,383 312 568 0.2260
2023-10-16 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,071 49 4.79 370 3.36 0.1656
2023-08-14 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,022 1,022 358 0.1555
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.