Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionGrandfield & Dodd, Llc
Latest Disclosed Ownership21,704 shares
Latest Disclosed Value $ 9,691,704
Grandfield & Dodd, Llc reports 2.23% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 7, 2026 - Grandfield & Dodd, Llc filed a 13F-HR form disclosing ownership of 21,704 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $9,691,704 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 10, 2026 disclosing 21,231 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 2.23% during the quarter. The current value of the position is $9,587,525 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-07 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 21,704 473 2.23 9,692 0.69 0.5472
2026-02-10 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 21,231 1,411 7.12 9,625 24.00 0.5452
2025-10-30 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 19,820 1,533 8.38 7,762 -4.66 0.4403
2025-08-08 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 18,287 141 0.78 8,141 -7.46 0.4768
2025-05-02 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 18,146 1,182 6.97 8,798 28.78 0.5455
2025-02-06 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 16,964 2,820 19.94 6,831 3.85 0.4212
2024-11-08 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 14,144 2,538 21.87 6,578 20.94 0.3898
2024-08-09 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 11,606 2,491 27.33 5,440 42.76 0.3444
2024-05-06 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 9,115 129 1.44 3,810 4.21 0.2404
2024-01-31 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 8,986 75 0.84 3,656 18.01 0.2526
2023-10-26 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 8,911 -107 -1.19 3,099 -2.36 0.2277
2023-08-08 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 9,018 30 0.33 3,174 12.08 0.2218
2023-04-28 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 8,988 151 1.71 2,832 10.98 0.1979
2023-01-20 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 8,837 234 2.72 2,552 2.45 0.1867
2022-11-04 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 8,603 0 0.00 2,490 2.89 0.2033
2022-08-01 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 8,603 13 0.15 2,420 8.04 0.1906
2022-04-19 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 8,590 150 1.78 2,240 21.08 0.1520
2022-02-08 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 8,440 519 6.55 1,850 28.47 0.1190
2021-10-28 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,921 -11 -0.14 1,440 -10.00 0.1005
2021-07-28 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,932 70 0.89 1,600 -5.33 0.1107
2021-04-22 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 7,862 19 0.24 1,690 -8.65 0.1264
2021-01-29 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 7,843 221 2.90 1,850 -10.63 0.1452
2020-11-03 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,622 38 0.50 2,070 -5.91 0.1864
2020-07-24 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,584 145 1.95 2,200 24.29 0.2129
2020-05-14 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 7,439 147 2.02 1,770 10.83 0.2087
2020-02-07 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 7,292 285 4.07 1,597 34.54 0.1455
2019-10-30 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,007 415 6.30 1,187 -1.82 0.1168
2019-07-29 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,592 312 4.97 1,209 4.68 0.1195
2019-04-26 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,280 41 0.66 1,155 11.70 0.1203
2019-02-12 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,239 61 0.99 1,034 -13.18 0.1224
2018-11-02 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,178 45 0.73 1,191 14.30 0.1227
2018-07-27 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,133 15 0.25 1,042 4.51 0.1145
2018-05-04 2018-03-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 6,118 -130 -2.08 997 6.52 0.1112
2018-05-04 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,118 -130 997
2018-02-05 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,248 103 1.68 936 0.21 0.0999
2017-11-03 2017-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,145 340 5.86 934 24.87 0.1049
2017-07-27 2017-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 5,805 90 1.57 748 19.68 0.0884
2017-04-28 2017-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 5,715 70 1.24 625 50.24 0.0772
2017-02-02 2016-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 5,645 500 9.72 416 -7.35 0.0539
2016-10-24 2016-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 5,145 305 6.30 449 7.93 0.0590
2016-07-28 2016-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 4,840 194 4.18 416 12.74 0.0582
2016-05-06 2016-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 4,646 1,520 48.62 369 -6.11 0.0534
2016-02-03 2015-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,126 505 19.27 393 43.96 0.0597
2015-11-02 2015-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,621 -100 -3.68 273 -18.75 0.0458
2015-08-03 2015-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,721 -86 -3.06 336 1.51 0.0514
2015-05-15 2015-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,807 0 0.00 331 -0.60 0.0506
2015-02-05 2014-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,807 0 0.00 333 5.71 0.0515
2014-11-10 2014-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,807 60 2.18 315 21.15 0.0495
2014-08-14 2014-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,747 2,747 260 0.0392
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.