Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionFred Alger Management, Llc
Latest Disclosed Ownership2,433 shares
Latest Disclosed Value $ 1,086,432
Fred Alger Management, Llc ownership in VRTX / Vertex Pharmaceuticals Incorporated

On May 15, 2026 - Fred Alger Management, Llc filed a 13F-HR form disclosing ownership of 2,433 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $1,086,432 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 2,433 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 0.00% during the quarter. The current value of the position is $1,042,151 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F Vertex Pharmaceuticals Equity 92532F100 2,433 0 0.00 1,086 -1.54 0.0030
2026-02-17 2025-12-31 13F Vertex Pharmaceuticals Equity 92532F100 2,433 -603 -19.86 1,103 -7.23 0.0043
2025-11-14 2025-09-30 13F Vertex Pharmaceuticals Equity 92532F100 3,036 -3,137 -50.82 1,189 -56.73 0.0046
2025-08-14 2025-06-30 13F Vertex Pharmaceuticals Equity 92532F100 6,173 -7,151 -53.67 2,748 -57.45 0.0123
2025-05-16 2025-03-31 13F Vertex Pharmaceuticals Equity 92532F100 13,324 8,062 153.21 6,460 204.81 0.0368
2025-02-14 2024-12-31 13F Vertex Pharmaceuticals Equity 92532F100 5,262 -12,773 -70.82 2,119 -74.73 0.0101
2024-11-14 2024-09-30 13F VERTEX PHARMACEUTICALS Common 92532F100 18,035 -42,168 -70.04 8,388 -70.28 0.0407
2024-08-14 2024-06-30 13F VERTEX PHARMACEUTICALS Common 92532F100 60,203 875 1.47 28,218 13.79 0.1372
2024-05-15 2024-03-31 13F VERTEX PHARMACEUTICALS Common 92532F100 59,328 -154,179 -72.21 24,800 -71.45 0.1230
2024-02-14 2023-12-31 13F VERTEX PHARMACEUTICALS Common 92532F100 213,507 -3,646 -1.68 86,874 15.05 0.4687
2023-11-14 2023-09-30 13F VERTEX PHARMACEUTICALS Common 92532F100 217,153 14,476 7.14 75,513 5.87 0.4003
2023-11-14 2023-09-30 13F VERTEX PHARMACEUTICALS Common 92532F100 217,153 75,513
2023-08-14 2023-06-30 13F VERTEX PHARMACEUTICALS Common 92532F100 202,677 32,509 19.10 71,324 33.03 0.3643
2023-05-16 2023-03-31 13F/A-1 VERTEX PHARMACEUTICALS Common 92532F100 170,168 -234,697 -57.97 53,615 -54.14 0.2867
2023-05-15 2023-03-31 13F VERTEX PHARMACEUTICALS Common 92532F100 170,168 -234,697 53,615 0.2659
2023-02-14 2022-12-31 13F VERTEX PHARMACEUTICALS Common 92532F100 404,865 -122,841 -23.28 116,917 -23.48 0.6337
2022-11-15 2022-09-30 13F VERTEX PHARMACEUTICALS Common 92532F100 527,706 29,367 5.89 152,792 8.81 0.7742
2022-08-15 2022-06-30 13F VERTEX PHARMACEUTICALS Common 92532F100 498,339 65,885 15.24 140,427 24.43 0.6558
2022-05-16 2022-03-31 13F VERTEX PHARMACEUTICALS Common 92532F100 432,454 42,908 11.01 112,858 31.93 0.3606
2022-02-14 2021-12-31 13F VERTEX PHARMACEUTICALS Common 92532F100 389,546 386,859 14,397.43 85,544 17,465.50 0.2143
2021-11-15 2021-09-30 13F VERTEX PHARMACEUTICALS Common 92532F100 2,687 -119 -4.24 487 -13.96 0.0012
2021-08-16 2021-06-30 13F VERTEX PHARMACEUTICALS Common 92532F100 2,806 -186,780 -98.52 566 -98.61 0.0013
2021-05-17 2021-03-31 13F VERTEX PHARMACEUTICALS Common 92532F100 189,586 -374,511 -66.39 40,740 -69.44 0.1066
2021-02-16 2020-12-31 13F VERTEX PHARMACEUTICALS Common 92532F100 564,097 -496,000 -46.79 133,319 -53.78 0.3469
2020-11-13 2020-09-30 13F VERTEX PHARMACEUTICALS Common 92532F100 1,060,097 -54,485 -4.89 288,474 -10.85 0.8375
2020-08-14 2020-06-30 13F VERTEX PHARMACEUTICALS Common 92532F100 1,114,582 -525,995 -32.06 323,574 -17.11 1.0661
2020-05-19 2020-03-31 13F/A-1 VERTEX PHARMACEUTICALS Common 92532F100 1,640,577 21,934 1.36 390,375 10.15 1.7154
2020-05-15 2020-03-31 13F VERTEX PHARMACEUTICALS Common 92532F100 1,640,577 21,934 390,375 1,717,554.4559
2020-02-14 2019-12-31 13F VERTEX PHARMACEUTICALS Common 92532F100 1,618,643 185,055 12.91 354,402 45.92 1.3044
2019-11-14 2019-09-30 13F VERTEX PHARMACEUTICALS Common 92532F100 1,433,588 99,046 7.42 242,878 -0.76 0.9530
2019-08-14 2019-06-30 13F VERTEX PHARMACEUTICALS Common 92532F100 1,334,542 -34,213 -2.50 244,728 -2.80 0.9400
2019-05-14 2019-03-31 13F VERTEX PHARMACEUTICALS Common 92532F100 1,368,755 -621,959 -31.24 251,782 -23.67 1.0027
2019-02-14 2018-12-31 13F VERTEX PHARMACEUTICALS Common 92532F100 1,990,714 4,013 0.20 329,881 -13.85 1.5186
2018-11-14 2018-09-30 13F VERTEX PHARMACEUTICALS Common 92532F100 1,986,701 26,208 1.34 382,917 14.92 1.4377
2018-07-19 2018-06-30 13F VERTEX PHARMACEUTICALS Common 92532F100 1,960,493 191,072 10.80 333,205 15.54 1.3989
2018-05-10 2018-03-31 13F VERTEX PHARMACEUTICALS Common 92532F100 1,769,421 -249,477 -12.36 288,380 -4.68 1.3408
2018-02-14 2017-12-31 13F VERTEX PHARMACEUTICALS Common 92532F100 2,018,898 293,215 16.99 302,552 15.31 1.3656
2017-11-14 2017-09-30 13F VERTEX PHARMACEUTICALS Common 92532F100 1,725,683 101,203 6.23 262,373 25.33 1.2272
2017-08-14 2017-06-30 13F VERTEX PHARMACEUTICALS Common 92532F100 1,624,480 414,501 34.26 209,347 58.22 0.9999
2017-05-15 2017-03-31 13F VERTEX PHARMACEUTICALS Common 92532F100 1,209,979 -153,622 -11.27 132,311 31.71 0.6585
2017-02-14 2016-12-31 13F VERTEX PHARMACEUTICALS Common 92532F100 1,363,601 -246,296 -15.30 100,456 -28.45 0.5466
2016-11-14 2016-09-30 13F VERTEX PHARMACEUTICALS Common 92532F100 1,609,897 6,793 0.42 140,399 1.81 0.7207
2016-08-15 2016-06-30 13F VERTEX PHARMACEUTICALS Common 92532F100 1,603,104 -365,385 -18.56 137,899 -11.87 0.7281
2016-05-16 2016-03-31 13F VERTEX PHARMACEUTICALS Common 92532F100 1,968,489 -313,802 -13.75 156,475 -45.51 0.7926
2016-02-16 2015-12-31 13F VERTEX PHARMACEUTICALS Common 92532F100 2,282,291 -157,576 -6.46 287,180 13.02 1.3966
2015-11-16 2015-09-30 13F VERTEX PHARMACEUTICALS Common 92532F100 2,439,867 1,640,824 205.35 254,088 157.52 1.3866
2015-08-14 2015-06-30 13F VERTEX PHARMACEUTICALS Common 92532F100 799,043 490,474 158.95 98,666 171.05 0.4440
2015-05-15 2015-03-31 13F VERTEX PHARMACEUTICALS Common 92532F100 308,569 82,086 36.24 36,402 35.29 0.1639
2015-02-17 2014-12-31 13F VERTEX PHARMACEUTICALS Common 92532F100 226,483 -138,698 -37.98 26,906 -34.40 0.1295
2014-11-14 2014-09-30 13F VERTEX PHARMACEUTICALS Common 92532F100 365,181 -8,203 -2.20 41,013 16.01 0.1995
2014-08-14 2014-06-30 13F VERTEX PHARMACEUTICALS Common 92532F100 373,384 -368,701 -49.68 35,352 -32.64 0.1741
2014-05-15 2014-03-31 13F VERTEX PHARMACEUTICALS Common 92532F100 742,085 139,608 23.17 52,480 17.24 0.2601
2014-02-14 2013-12-31 13F VERTEX PHARMACEUTICALS Common 92532F100 602,477 -113,038 -15.80 44,764 -17.49 0.2282
2013-11-14 2013-09-30 13F VERTEX PHARMACEUTICALS Common 92532F100 715,515 -428,408 -37.45 54,251 -40.76 0.3017
2013-08-14 2013-06-30 13F VERTEX PHARMACEUTICALS Common 92532F100 1,143,923 1,143,923 91,582 0.5442
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.