Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionFlagship Harbor Advisors, Llc
Latest Disclosed Ownership1,644 shares
Latest Disclosed Value $ 734,112
Flagship Harbor Advisors, Llc reports 4.51% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On April 28, 2026 - Flagship Harbor Advisors, Llc filed a 13F-HR form disclosing ownership of 1,644 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $734,112 USD as of March 31, 2026. The entity filed a previous 13F-HR on January 21, 2026 disclosing 1,573 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 4.51% during the quarter. The current value of the position is $704,191 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-04-28 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,644 71 4.51 734 2.95 0.0323
2026-01-21 2025-12-31 13F VERTEX PHARMACEUTICALS Common Stock 92532F100 1,573 -17 -1.07 713 14.63 0.0337
2025-11-05 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,590 -30 -1.85 623 -13.73 0.0271
2025-08-04 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,620 85 5.54 721 -3.09 0.0342
2025-04-22 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,535 13 0.85 744 21.57 0.0391
2025-01-21 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,522 0 0.00 613 -13.44 0.0322
2024-10-21 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,522 -444 -22.58 708 -23.24 0.0389
2025-12-02 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,966 58 3.04 922 15.56 0.0554
2024-04-16 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,908 -4 -0.21 798 2.57 0.0513
2024-01-10 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,912 341 21.71 778 42.31 0.0566
2023-10-17 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,571 70 4.66 546 3.41 0.0454
2023-07-11 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,501 100 7.14 528 19.73 0.0436
2023-04-12 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,401 -261 -15.70 441 -7.93 0.0416
2023-01-13 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,662 -62 -3.60 480 -4.01 0.0492
2022-10-13 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,724 406 30.80 499 34.50 0.0579
2022-07-13 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,318 14 1.07 371 9.12 0.0417
2022-04-13 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,304 -12 -0.91 340 17.65 0.0328
2022-02-17 2021-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 1,316 214 19.42 289 30.18 0.0273
2022-02-10 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,316 214 289 0.0273
2021-11-01 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,102 0 0.00 222 0.00 0.0239
2021-07-26 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,102 1,102 222 0.0238
2021-02-08 2020-12-31 13F VERTEX PHARMACEUTICALS Common Stock 92532F100 0 -794 -100.00 0 -100.00
2020-10-13 2020-09-30 13F VERTEX PHARMACEUTICALS Common Stock 92532F100 794 74 10.28 216 3.35 0.0292
2020-07-31 2020-06-30 13F VERTEX PHARMACEUTICALS Common Stock 92532F100 720 148 25.87 209 53.68 0.0307
2020-05-12 2020-03-31 13F VERTEX PHARMACEUTICALS Common Stock 92532F100 572 58 11.28 136 20.35 0.0272
2020-02-14 2019-12-31 13F VERTEX PHARMACEUTICALS Common Stock 92532F100 514 0 0.00 113 29.89 0.0198
2019-10-22 2019-09-30 13F VERTEX PHARMACEUTICALS Common Stock 92532F100 514 0 0.00 87 -7.45 0.0171
2019-07-22 2019-06-30 13F VERTEX PHARMACEUTICALS Common Stock 92532F100 514 16 3.21 94 3.30 0.0195
2019-04-15 2019-03-31 13F VERTEX PHARMACEUTICALS Common Stock 92532F100 498 0 0.00 91 10.98 0.0187
2019-01-26 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 498 -228 -31.40 82 -41.01 0.0199
2018-11-05 2018-09-30 13F VERTEX PHARMACEUTICALS Common Stock 92532F100 726 -11 -1.49 139 11.20 0.0258
2018-08-14 2018-06-30 13F VERTEX PHARM Common Stock 92532F100 737 737 125 0.0250
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.