Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionFirst Citizens Bank & Trust Co
Latest Disclosed Ownership1,092 shares
Latest Disclosed Value $ 487,621
First Citizens Bank & Trust Co reports 20.00% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 13, 2026 - First Citizens Bank & Trust Co filed a 13F-HR form disclosing ownership of 1,092 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $487,622 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 18, 2026 disclosing 910 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 20.00% during the quarter. The current value of the position is $487,938 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-13 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,092 182 20.00 488 18.20 0.0103
2026-02-18 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 910 -730 -44.51 413 -35.83 0.0086
2025-10-31 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,640 37 2.31 642 -9.96 0.0138
2025-07-30 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,603 -2,594 -61.81 714 -64.95 0.0129
2025-04-14 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 4,197 -639 -13.21 2,035 4.47 0.0517
2025-01-21 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 4,836 -21,153 -81.39 1,947 -83.89 0.0357
2024-10-17 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 25,989 -1,410 -5.15 12,087 -5.89 0.2656
2024-07-19 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 27,399 -411 -1.48 12,842 10.48 0.2423
2024-04-15 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 27,810 6,414 29.98 11,625 33.53 0.2227
2024-01-22 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 21,396 -647 -2.94 8,706 13.57 0.1581
2023-10-30 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 22,043 -3,761 -14.58 7,665 -15.58 0.1493
2023-08-15 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 25,804 5,908 29.69 9,081 44.86 0.1669
2023-05-11 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 19,896 8,602 76.16 6,269 208,833.33 0.1251
2023-01-24 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 11,294 -80 -0.70 3 -99.91 0.0988
2022-10-20 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 11,374 -2,619 -18.72 3,293 -16.48 0.1081
2022-07-26 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 13,993 543 4.04 3,943 12.34 0.1394
2022-04-26 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 13,450 483 3.72 3,510 23.24 0.1364
2022-03-11 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 12,967 164 1.28 2,848 22.65 0.1114
2021-10-15 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 12,803 -1,165 -8.34 2,322 -17.54 0.1109
2021-07-14 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 13,968 -751 -5.10 2,816 -10.97 0.1335
2021-04-14 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 14,719 269 1.86 3,163 -7.38 0.1491
2021-01-13 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 14,450 -484 -3.24 3,415 -15.97 0.1744
2020-10-15 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 14,934 1,598 11.98 4,064 4.96 0.2863
2020-07-15 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 13,336 4,706 54.53 3,872 88.51 0.3236
2020-04-17 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 8,630 5,518 177.31 2,054 201.62 0.2483
2020-01-15 2019-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 3,112 3,112 681 0.0655
2019-10-17 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -5,442 -100.00 0 -100.00
2019-07-11 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 5,442 0 0.00 1,001 0.00 0.1115
2019-04-12 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 5,442 570 11.70 1,001 24.04 0.1115
2019-01-15 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 4,872 4,872 807 0.0981
2018-07-11 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -4,798 -100.00 0 -100.00
2018-04-11 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 4,798 4,798 782 0.1063
2018-01-10 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -2,720 -100.00 0 -100.00
2017-10-12 2017-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,720 -19,206 -87.59 414 -75.09 0.0539
2013-10-25 2013-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 21,926 2,456 12.61 1,662 6.61 0.0635
2013-08-06 2013-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 19,470 19,470 1,559 0.0640
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.