Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionEmpirical Financial Services, LLC d.b.a. Empirical Wealth Management
Latest Disclosed Ownership659 shares
Latest Disclosed Value $ 294,271
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management reports 64.01% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 4, 2026 - Empirical Financial Services, LLC d.b.a. Empirical Wealth Management filed a 13F-HR form disclosing ownership of 659 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $294,270 USD as of March 31, 2026. The entity filed a previous 13F-HR on January 16, 2026 disclosing 1,831 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -64.01% during the quarter. The current value of the position is $294,461 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-04 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 659 -1,172 -64.01 294 -64.58 0.0035
2026-01-16 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,831 156 9.31 830 26.72 0.0148
2025-11-10 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,675 -377 -18.37 656 -28.26 0.0131
2025-07-21 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,052 215 11.70 914 2.58 0.0206
2025-05-08 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,837 1,146 165.85 891 220.14 0.0229
2025-01-22 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 691 -153 -18.13 278 -29.08 0.0075
2024-11-01 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 844 -3 -0.35 393 -1.26 0.0110
2024-08-09 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 847 -404 -32.29 397 -23.95 0.0118
2024-05-07 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,251 203 19.37 523 22.54 0.0158
2024-02-06 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,048 68 6.94 426 25.29 0.0142
2023-11-03 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 980 -21 -2.10 341 -3.41 0.0133
2023-08-11 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,001 -345 -25.63 352 -16.98 0.0142
2023-05-09 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,346 0 0.00 424 9.28 0.0184
2023-02-08 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,346 -39 -2.82 389 -3.24 0.0183
2022-11-03 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,385 -393 -22.10 401 -19.96 0.0210
2022-08-02 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 1,778 -307 -14.72 501 -7.90 0.0263
2022-05-13 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,085 -1,815 -46.54 544 -36.45 0.0271
2022-02-14 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,900 -2,072 -34.70 856 -20.96 0.0427
2021-11-02 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 5,972 2,031 51.54 1,083 36.23 0.0617
2021-08-12 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,941 1,529 63.39 795 53.47 0.0481
2021-05-17 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,412 2,412 518 0.0415
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.