Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionCrestwood Advisors Group LLC
Latest Disclosed Ownership7,756 shares
Latest Disclosed Value $ 3,463,303
Crestwood Advisors Group LLC reports 3.09% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 5, 2026 - Crestwood Advisors Group LLC filed a 13F-HR form disclosing ownership of 7,756 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $3,463,364 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 3, 2026 disclosing 8,003 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -3.09% during the quarter. The current value of the position is $3,465,613 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-05 2026-03-31 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 7,756 -247 -3.09 3,463 -4.55 0.0580
2026-02-03 2025-12-31 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 8,003 -1,148 -12.55 3,628 1.26 0.0604
2025-11-07 2025-09-30 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 9,151 -892 -8.88 3,584 -19.86 0.0609
2025-08-05 2025-06-30 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 10,043 -232 -2.26 4,471 -10.24 0.0801
2025-05-05 2025-03-31 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 10,275 4,476 77.19 4,982 113.32 0.0947
2025-02-04 2024-12-31 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 5,799 121 2.13 2,335 -11.55 0.0438
2024-10-30 2024-09-30 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 5,678 46 0.82 2,641 0.04 0.0504
2024-08-01 2024-06-30 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 5,632 99 1.79 2,640 14.14 0.0546
2024-05-08 2024-03-31 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 5,533 436 8.55 2,313 11.48 0.0505
2024-02-13 2023-12-31 13F/A-1 VERTEX PHARMACEUTICALS INC COM Stock 92532F100 5,097 90 1.80 2,074 19.13 0.0483
2024-01-29 2023-12-31 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 5,097 90 2,074 0.0482
2023-11-15 2023-09-30 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 5,007 5,007 1,741 0.0457
2021-04-21 2021-03-31 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 0 -1,230 -100.00 0 -100.00
2021-02-09 2020-12-31 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 1,230 -178 -12.64 291 -24.02 0.0096
2020-10-06 2020-09-30 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 1,408 3 0.21 383 -6.13 0.0144
2020-08-14 2020-06-30 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 1,405 -7 -0.50 408 21.43 0.0163
2020-05-15 2020-03-31 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 1,412 7 0.50 336 9.09 0.0167
2020-02-12 2019-12-31 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 1,405 -50 -3.44 308 24.70 0.0122
2019-11-13 2019-09-30 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 1,455 -1 -0.07 247 -7.49 0.0109
2019-08-14 2019-06-30 13F VERTEX PHARMACEUTICALS INC COM Stock 92532F100 1,456 1,456 267 0.0121
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.