Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionCibc World Markets Corp
Latest Disclosed Ownership47,710 shares
Latest Disclosed Value $ 21,629,806
Cibc World Markets Corp reports 5.72% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On February 12, 2026 - Cibc World Markets Corp filed a 13F-HR form disclosing ownership of 47,710 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $21,629,806 USD as of December 31, 2025. The entity filed a previous 13F-HR on August 14, 2025 disclosing 50,606 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -5.72% during the quarter. The current value of the position is $21,318,259 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-02-12 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 47,710 -2,896 -5.72 21,630 -3.99 0.1041
2025-08-14 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 50,606 19,599 63.21 22,530 49.87 0.1413
2025-05-13 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 31,007 -15,332 -33.09 15,033 -19.44 0.1182
2025-02-10 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 46,339 5,665 13.93 18,661 -1.35 0.1093
2024-11-13 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 40,674 -11,254 -21.67 18,917 -22.28 0.1364
2024-08-12 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 51,928 9,069 21.16 24,340 35.86 0.1594
2024-05-13 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 42,859 -48,560 -53.12 17,915 -51.84 0.1175
2024-02-13 2023-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 91,419 47,483 108.07 37,197 143.47 0.2027
2023-11-13 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 43,936 -7,821 -15.11 15,278 -16.11 0.1496
2023-08-04 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 51,757 35,671 221.75 18,214 259.37 0.1479
2023-05-11 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 16,086 -17,144 -51.59 5,068 -47.19 0.0827
2023-02-09 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 33,230 29,339 754.02 9,596 751.46 0.0646
2022-11-14 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 3,891 -28,220 -87.88 1,127 -87.55 0.0157
2022-08-12 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 32,111 -27,629 -46.25 9,049 -41.96 0.0850
2022-05-13 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 59,740 59,740 15,590 0.1218
2022-02-11 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -68,765 -100.00 0 -100.00
2021-11-12 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 68,765 47,986 230.94 12,473 197.68 0.0848
2021-08-10 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 20,779 -110,750 -84.20 4,190 -85.18 0.0292
2021-05-07 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 131,529 60,367 84.83 28,264 68.06 0.1763
2021-02-12 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 71,162 25,297 55.16 16,818 34.75 0.0846
2020-11-12 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 45,865 3,648 8.64 12,481 1.84 0.1216
2020-08-12 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 42,217 -30,555 -41.99 12,256 -29.22 0.1315
2020-05-12 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 72,772 21,379 41.60 17,316 53.89 0.2212
2020-02-13 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 51,393 -50,204 -49.41 11,252 -34.63 0.0729
2019-11-12 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 101,597 43,073 73.60 17,213 60.39 0.1606
2019-08-13 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 58,524 -2,674 -4.37 10,732 -4.66 0.0827
2019-05-14 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 61,198 -89,538 -59.40 11,257 -54.93 0.0921
2019-02-13 2018-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 150,736 73,901 96.18 24,978 68.67 0.2325
2019-02-13 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 150,736 73,901 24,978
2018-11-13 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 76,835 20,202 35.67 14,809 53.86 0.1263
2018-08-13 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 56,633 9,571 20.34 9,625 25.49 0.0831
2018-05-11 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 47,062 -28,065 -37.36 7,670 -31.88 0.0816
2018-02-13 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 75,127 17,596 30.59 11,259 28.72 0.0809
2017-11-14 2017-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 57,531 3,783 7.04 8,747 26.27 0.0839
2017-08-11 2017-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 53,748 27,816 107.27 6,927 144.25 0.0733
2017-05-10 2017-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 25,932 8,885 52.12 2,836 125.80 0.0230
2017-02-13 2016-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 17,047 11,984 236.70 1,256 184.16 0.0129
2016-11-14 2016-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 5,063 -11,602 -69.62 442 -69.18 0.0084
2016-08-11 2016-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 16,665 1,573 10.42 1,434 19.50 0.0372
2016-05-12 2016-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 15,092 -5,598 -27.06 1,200 -53.90 0.0263
2016-02-10 2015-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 20,690 3,760 22.21 2,603 47.65 0.0530
2015-11-16 2015-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 16,930 9,926 141.72 1,763 103.82 0.0475
2015-08-14 2015-06-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 7,004 0 865 0.0035
2015-08-19 2015-06-30 13F/A-2 VERTEX PHARMACEUTICALS COM 92532F100 7,004 0 865 0.0036
2015-11-20 2015-06-30 13F/A-3 VERTEX PHARMACEUTICALS COM 92532F100 7,004 7,004 865 0.0273
2015-08-13 2015-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,004 865 0.0036
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.