Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionCastleark Management Llc
Latest Disclosed Ownership730 shares
Latest Disclosed Value $ 325,974
Castleark Management Llc ownership in VRTX / Vertex Pharmaceuticals Incorporated

On May 15, 2026 - Castleark Management Llc filed a 13F-HR form disclosing ownership of 730 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $325,974 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 730 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 0.00% during the quarter. The current value of the position is $312,688 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 730 0 0.00 326 -1.52 0.0108
2026-02-12 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 730 0 0.00 331 15.79 0.0097
2025-11-17 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 730 0 0.00 286 -12.04 0.0080
2025-08-18 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 730 -46,309 -98.45 325 -98.58 0.0098
2025-05-15 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 47,039 554 1.19 22,805 21.83 0.7904
2025-02-18 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 46,485 -36,240 -43.81 18,720 -51.35 0.6529
2024-11-15 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 82,725 35,922 76.75 38,474 75.38 1.5683
2024-08-14 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 46,803 46,073 6,311.37 21,938 7,092.46 0.8961
2024-05-16 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 730 0 0.00 305 2.69 0.0127
2024-02-15 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 730 0 0.00 297 17.39 0.0132
2023-11-15 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 730 0 0.00 254 -1.17 0.0129
2023-08-16 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 730 0 0.00 257 11.30 0.0116
2023-05-16 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 730 0 0.00 230 9.52 0.0113
2023-02-10 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 730 0 0.00 211 -0.47 0.0110
2022-11-15 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 730 0 0.00 211 2.43 0.0117
2022-08-16 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 730 0 0.00 206 7.85 0.0110
2022-05-16 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 730 0 0.00 191 19.38 0.0082
2022-02-16 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 730 0 0.00 160 21.21 0.0059
2021-11-12 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 730 0 0.00 132 -10.20 0.0050
2021-08-17 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 730 0 0.00 147 -6.37 0.0049
2021-05-14 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 730 0 0.00 157 -9.25 0.0057
2021-02-17 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 730 -200 -21.51 173 -31.62 0.0065
2020-11-16 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 930 0 0.00 253 -6.30 0.0099
2020-08-14 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 930 -104,130 -99.11 270 -98.92 0.0117
2020-05-13 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 105,060 38,240 57.23 24,999 70.87 1.4802
2020-02-14 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 66,820 65,890 7,084.95 14,630 9,159.49 0.5855
2019-11-15 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 930 -10,180 -91.63 158 -92.24 0.0064
2019-08-13 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 11,110 -15,720 -58.59 2,037 -58.72 0.0781
2019-05-14 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 26,830 0 0.00 4,935 11.00 0.1858
2019-02-12 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 26,830 0 0.00 4,446 -14.02 0.1895
2018-11-14 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 26,830 0 0.00 5,171 13.40 0.1486
2018-08-15 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 26,830 0 0.00 4,560 4.28 0.1404
2018-05-14 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 26,830 0 0.00 4,373 8.75 0.1385
2018-02-15 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 26,830 0 0.00 4,021 -1.42 0.1207
2017-11-15 2017-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 26,830 0 0.00 4,079 17.96 0.1280
2017-08-15 2017-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 26,830 0 0.00 3,458 17.86 0.1130
2017-05-15 2017-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 26,830 0 0.00 2,934 48.41 0.0919
2017-02-15 2016-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 26,830 0 0.00 1,977 -15.51 0.0631
2016-11-15 2016-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 26,830 0 0.00 2,340 1.39 0.0708
2016-08-10 2016-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 26,830 0 0.00 2,308 8.20 0.0736
2016-05-17 2016-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 26,830 0 0.00 2,133 -36.82 0.0666
2016-02-17 2015-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 26,830 -4,000 -12.97 3,376 5.14 0.1015
2015-11-17 2015-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 30,830 0 0.00 3,211 -15.66 0.1033
2015-08-17 2015-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 30,830 0 0.00 3,807 4.67 0.1017
2015-05-15 2015-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 30,830 0 0.00 3,637 -0.71 0.0877
2015-02-10 2014-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 30,830 -1,000 -3.14 3,663 62.73 0.0944
2014-11-17 2014-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 31,830 0 0.00 2,251 -25.32 0.0640
2014-08-15 2014-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 31,830 0 0.00 3,014 33.90 0.0831
2014-05-20 2014-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 31,830 0 0.00 2,251 -4.82 0.0640
2014-02-20 2013-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 31,830 1,000 3.24 2,365 -31.71 0.0687
2014-11-21 2013-09-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 30,830 -6,500 -17.41 3,463 15.86 0.0976
2013-11-20 2013-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 37,330 2,830
2013-09-26 2013-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 37,330 37,330 2,989 0.0992
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.