Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionBoston Private Wealth Llc
Latest Disclosed Ownership2,844 shares
Latest Disclosed Value $ 1,269,514
Boston Private Wealth Llc reports 7.09% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On April 17, 2026 - Boston Private Wealth Llc filed a 13F-HR form disclosing ownership of 2,844 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $1,269,960 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 4, 2026 disclosing 3,061 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -7.09% during the quarter. The current value of the position is $1,270,785 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-04-17 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,844 -217 -7.09 1,270 -8.51 0.0836
2026-02-04 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 3,061 -4,354 -58.72 1,388 -52.24 0.0818
2025-11-06 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,415 -92 -1.23 2,904 -13.11 0.1563
2025-08-14 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,507 -3,129 -29.42 3,342 -35.18 0.1791
2025-05-14 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 10,636 -4,527 -29.86 5,156 -15.56 0.2119
2025-02-05 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 15,163 15,163 6,106 0.1141
2024-10-18 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -17,201 -100.00 0 -100.00
2024-08-06 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 17,201 63 0.37 8,062 12.55 0.1996
2024-05-15 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 17,138 -56 -0.33 7,164 2.39 0.1597
2024-01-30 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 17,194 -148 -0.85 6,996 16.02 0.1702
2023-10-23 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 17,342 -211 -1.20 6,031 -2.38 0.1324
2023-07-24 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 17,553 -474 -2.63 6,177 8.77 0.1116
2023-05-12 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 18,027 -433 -2.35 5,680 6.55 0.0794
2023-02-10 2022-12-31 13F Vertex Pharmaceuticals COM 92532F100 18,460 -264 -1.41 5,331 -1.70 0.0720
2022-11-09 2022-09-30 13F Vertex Pharmaceuticals COM 92532F100 18,724 1,559 9.08 5,422 12.09 0.0792
2022-08-16 2022-06-30 13F Vertex Pharmaceuticals COM 92532F100 17,165 297 1.76 4,837 9.88 0.0744
2022-05-13 2022-03-31 13F Vertex Pharmaceuticals COM 92532F100 16,868 496 3.03 4,402 22.45 0.0590
2022-02-15 2021-12-31 13F Vertex Pharmaceuticals COM 92532F100 16,372 98 0.60 3,595 21.78 0.0590
2021-11-09 2021-09-30 13F Vertex Pharmaceuticals COM 92532F100 16,274 -812 -4.75 2,952 -14.31 0.0379
2021-08-13 2021-06-30 13F Vertex Pharmaceuticals COM 92532F100 17,086 321 1.91 3,445 -4.36 0.0437
2021-05-11 2021-03-31 13F Vertex Pharmaceuticals COM 92532F100 16,765 1,345 8.72 3,602 -1.15 0.0502
2021-02-10 2020-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 15,420 343 2.27 3,644 -11.19 0.0535
2020-11-10 2020-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 15,077 973 6.90 4,103 0.20 0.0677
2020-08-05 2020-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 14,104 475 3.49 4,095 26.27 0.0761
2020-05-11 2020-03-31 13F Vertex Pharmaceuticals COM 92532F100 13,629 -443 -3.15 3,243 5.26 0.0787
2020-02-13 2019-12-31 13F Vertex Pharmaceuticals COM 92532F100 14,072 207 1.49 3,081 31.16 0.0561
2019-11-01 2019-09-30 13F Vertex Pharmaceuticals COM 92532F100 13,865 540 4.05 2,349 -3.89 0.0468
2019-07-10 2019-06-30 13F Vertex Pharmaceuticals COM 92532F100 13,325 0 0.00 2,444 -0.29 0.0821
2019-05-14 2019-03-31 13F Vertex Pharmaceuticals COM 92532F100 13,325 -44 -0.33 2,451 10.65 0.0968
2019-02-14 2018-12-31 13F Vertex Pharmaceuticals COM 92532F100 13,369 -144 -1.07 2,215 -14.94 0.0945
2018-11-13 2018-09-30 13F Vertex Pharmaceuticals COM 92532F100 13,513 -208 -1.52 2,604 11.66 0.0921
2018-08-14 2018-06-30 13F Vertex Pharmaceuticals COM 92532F100 13,721 -125 -0.90 2,332 3.32 0.0894
2018-05-11 2018-03-31 13F Vertex Pharmaceuticals COM 92532F100 13,846 -245 -1.74 2,257 6.87 0.0866
2018-02-13 2017-12-31 13F Vertex Pharmaceuticals COM 92532F100 14,091 -782 -5.26 2,112 -6.59 0.0795
2017-11-13 2017-09-30 13F Vertex Pharmaceuticals COM 92532F100 14,873 18 0.12 2,261 18.13 0.0870
2017-08-04 2017-06-30 13F Vertex Pharmaceuticals COM 92532F100 14,855 0 0.00 1,914 17.86 0.0751
2017-05-11 2017-03-31 13F Vertex Pharmaceuticals COM 92532F100 14,855 -3,455 -18.87 1,624 20.39 0.0647
2017-02-15 2016-12-31 13F Vertex Pharmaceuticals COM 92532F100 18,310 -571 -3.02 1,349 -18.09 0.0558
2016-11-15 2016-09-30 13F/A-1 Vertex Pharmaceuticals COM 92532F100 18,881 -1,153 -5.76 1,647 -4.41 0.0670
2016-11-14 2016-09-30 13F Vertex Pharmaceuticals COM 92532F100 20,034 0 1,723 0.0703
2016-08-01 2016-06-30 13F Vertex Pharmaceuticals COM 92532F100 20,034 -1,551 -7.19 1,723 0.41 0.0703
2016-05-13 2016-03-31 13F Vertex Pharmaceuticals COM 92532F100 21,585 -853 -3.80 1,716 -39.21 0.0699
2016-02-12 2015-12-31 13F Vertex Pharmaceuticals COM 92532F100 22,438 -883 -3.79 2,823 16.22 0.1114
2015-11-12 2015-09-30 13F Vertex Pharmaceuticals COM 92532F100 23,321 -2,894 -11.04 2,429 -24.96 0.0942
2015-08-13 2015-06-30 13F Vertex Pharmaceuticals COM 92532F100 26,215 420 1.63 3,237 6.38 0.1071
2015-05-12 2015-03-31 13F Vertex Pharmaceuticals COM 92532F100 25,795 920 3.70 3,043 2.98 0.0982
2015-02-10 2014-12-31 13F Vertex Pharmaceuticals COM 92532F100 24,875 24,875 2,955 0.0956
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.