Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionBlair William & Co/il
Latest Disclosed Ownership16,541 shares
Latest Disclosed Value $ 7,386,220
Blair William & Co/il reports 2.80% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 8, 2026 - Blair William & Co/il filed a 13F-HR form disclosing ownership of 16,541 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $7,386,218 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 16,090 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 2.80% during the quarter. The current value of the position is $7,391,015 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-08 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 16,541 451 2.80 7,386 1.26 0.0212
2026-02-17 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 16,090 -1,900 -10.56 7,294 3.53 0.0196
2025-11-12 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 17,990 -8,087 -31.01 7,046 -39.31 0.0188
2025-07-24 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 26,077 -768 -2.86 11,610 -10.80 0.0322
2025-05-09 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 26,845 201 0.75 13,015 21.31 0.0393
2025-02-12 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 26,644 -64,672 -70.82 10,730 -74.74 0.0312
2024-11-12 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 91,316 2,208 2.48 42,469 1.68 0.1247
2024-08-12 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 89,108 18,197 25.66 41,767 40.91 0.1288
2024-05-09 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 70,911 6,937 10.84 29,642 13.87 0.0931
2024-02-12 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 63,974 45,128 239.46 26,030 297.22 0.0887
2023-11-09 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 18,846 581 3.18 6,554 1.96 0.0251
2023-08-11 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 18,265 73 0.40 6,428 12.14 0.0235
2023-05-12 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 18,192 548 3.11 5,732 12.48 0.0229
2023-02-10 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 17,644 -169 -0.95 5,095 -1.22 0.0222
2022-11-09 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 17,813 -142 -0.79 5,158 1.94 0.0237
2022-08-10 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 17,955 -578 -3.12 5,060 4.61 0.0224
2022-05-13 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 18,533 -4,956 -21.10 4,837 -6.22 0.0170
2022-02-14 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 23,489 7,239 44.55 5,158 74.97 0.0162
2021-11-12 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 16,250 -6,500 -28.57 2,948 -35.73 0.0100
2021-08-12 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 22,750 -3,289 -12.63 4,587 -18.03 0.0159
2021-05-13 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 26,039 -2,370 -8.34 5,596 -16.65 0.0211
2021-02-09 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 28,409 -4,316 -13.19 6,714 -24.60 0.0246
2020-11-06 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 32,725 -17 -0.05 8,905 -6.31 0.0378
2020-08-12 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 32,742 5,319 19.40 9,505 45.67 0.0453
2020-05-11 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 27,423 135 0.49 6,525 9.21 0.0408
2020-02-13 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 27,288 4,945 22.13 5,975 57.86 0.0307
2019-11-12 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 22,343 -1,383 -5.83 3,785 -13.01 0.0218
2019-08-13 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 23,726 5,467 29.94 4,351 29.53 0.0249
2019-05-14 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 18,259 10,327 130.19 3,359 155.63 0.0205
2019-02-14 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 7,932 1,669 26.65 1,314 8.86 0.0096
2018-11-13 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,263 47 0.76 1,207 14.30 0.0074
2018-08-13 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,216 157 2.59 1,056 6.99 0.0072
2018-05-15 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,059 42 0.70 987 9.42 0.0070
2018-02-14 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,017 14 0.23 902 -1.20 0.0061
2017-11-13 2017-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,003 -8 -0.13 913 17.81 0.0068
2017-08-04 2017-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,011 0 0.00 775 20.16 0.0058
2017-05-10 2017-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,011 -110 -1.80 645 43.02 0.0052
2017-02-14 2016-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,121 -1,149 -15.80 451 -28.86 0.0040
2016-11-14 2016-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,270 -3 -0.04 634 1.28 0.0056
2016-08-08 2016-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,273 309 4.44 626 13.20 0.0058
2016-05-16 2016-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,964 565 8.83 553 -31.30 0.0052
2016-02-16 2015-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,399 -7,896 -55.24 805 -45.90 0.0076
2015-11-12 2015-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 14,295 7,826 120.98 1,488 86.47 0.0129
2015-08-03 2015-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,469 0 0.00 798 4.72 0.0012
2015-05-11 2015-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,469 6,469 0.00 762 0.0012
2015-02-05 2014-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -6,270 -100.00 0 -100.00
2014-11-04 2014-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,270 34 0.55 704 19.32 0.0012
2014-08-01 2014-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,236 -698 -10.07 590 20.41 0.0010
2014-05-06 2014-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,934 344 5.22 490 0.00 0.0008
2014-02-11 2013-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,590 -1,065 -13.91 490 -15.52 0.0008
2013-11-12 2013-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,655 -1,915 -20.01 580 -24.08 0.0010
2013-08-07 2013-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 9,570 9,570 764 0.0015
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.