Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionCIBC Private Wealth Group, LLC
Latest Disclosed Ownership7,087 shares
Latest Disclosed Value $ 3,212,962
CIBC Private Wealth Group, LLC reports 4.25% increase in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On February 12, 2026 - CIBC Private Wealth Group, LLC filed a 13F-HR form disclosing ownership of 7,087 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $3,212,962 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 24, 2025 disclosing 6,798 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 4.25% during the quarter. The current value of the position is $3,166,684 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-02-12 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 7,087 289 4.25 3,213 20.66 0.0054
2025-11-24 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,798 -231 -3.29 2,662 -14.92 0.0046
2025-08-12 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,029 467 7.12 3,129 0.97 0.0056
2025-05-14 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,562 508 8.39 3,100 24.26 0.0065
2025-02-12 2024-12-31 13F Vertex Pharmaceuticals COM 92532F100 6,054 -424 -6.55 2,495 -17.20 0.0045
2024-11-13 2024-09-30 13F Vertex Pharmaceuticals COM 92532F100 6,478 -4,304 -39.92 3,013 -42.02 0.0054
2024-08-09 2024-06-30 13F Vertex Pharmaceuticals COM 92532F100 10,782 8,003 287.98 5,196 344.78 0.0097
2024-05-10 2024-03-31 13F Vertex Pharmaceuticals COM 92532F100 2,779 -163 -5.54 1,169 -2.34 0.0023
2024-02-13 2023-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 2,942 -2,748 -48.30 1,197 -39.53 0.0025
2023-11-13 2023-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 5,690 4,052 247.37 1,979 243.40 0.0047
2023-11-21 2023-06-30 13F/A-1 VERTEX PHARMACEUTICALS INC COM COM 92532F100 1,638 2 0.12 576 11.84 0.0013
2023-08-10 2023-06-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 1,638 2 576 0.0013
2023-11-21 2023-03-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 1,636 -7,180 -81.44 515 -79.76 0.0011
2023-05-12 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,636 -7,180 515 0.0011
2023-06-01 2022-12-31 13F/A-2 VERTEX PHARMACEUTICA COM 92532F100 8,816 4,689 113.62 2,546 112.97 0.0086
2023-02-14 2022-12-31 13F/A-1 VERTEX PHARMACEUTICALS INC COM COM 92532F100 8,816 4,689 2,546 0.0053
2023-02-13 2022-12-31 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 8,816 4,689 2,180 0.0000
2022-11-15 2022-09-30 13F VERTEX PHARMACEUTICALS INC COM COM 92532F100 4,127 -5,049 -55.02 1,195 -53.79 0.0032
2022-08-03 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 9,176 -12,348 -57.37 2,586 -53.97 0.0067
2022-05-16 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 21,524 19,011 756.51 5,618 917.75 0.0123
2022-04-04 2021-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 2,513 21 0.84 552 22.12 0.0011
2022-02-08 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 2,513 21 552 0.0011
2021-11-12 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,492 -32,524 -92.88 452 -93.60 0.0011
2021-08-16 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 35,016 -2,412 -6.44 7,060 -12.21 0.0162
2021-05-12 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 37,428 9,171 32.46 8,042 20.43 0.0202
2021-02-12 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 28,257 -172,320 -85.91 6,678 -87.76 0.0177
2020-11-03 2020-09-30 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 200,577 200,577 54,581 0.1672
2020-08-13 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -161,997 -100.00 0 -100.00
2020-05-15 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 161,997 160,523 10,890.30 38,547 11,834.06 0.1653
2020-01-30 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 1,474 1,474 323 0.0011
2019-10-16 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -2,495 -100.00 0 -100.00
2019-07-31 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 2,495 2,495 458 0.0016
2019-02-05 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -7,653 -100.00 0 -100.00
2018-11-14 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,653 7,199 1,585.68 1,475 1,815.58 0.0056
2018-08-02 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 454 -171 -27.36 77 -24.51 0.0003
2018-05-17 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 625 243 63.61 102 78.95 0.0004
2018-02-12 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 382 -11,352 -96.74 57 -96.80 0.0002
2017-12-21 2017-09-30 13F/A-1 VERTEX PHARMACEUTCLS COM 92532F100 11,734 11,734 1,784 0.0081
2017-11-14 2017-09-30 13F VERTEX PHARMACEUTCLS COM 92532F100 11,734 1,784 0.0080
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.