Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionArizona State Retirement System
Latest Disclosed Ownership69,515 shares
Latest Disclosed Value $ 31,041,228
Arizona State Retirement System reports 3.84% decrease in ownership of VRTX / Vertex Pharmaceuticals Incorporated

On May 1, 2026 - Arizona State Retirement System filed a 13F-HR form disclosing ownership of 69,515 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $31,041,228 USD as of March 31, 2026. The entity filed a previous 13F-HR on January 28, 2026 disclosing 72,293 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -3.84% during the quarter. The current value of the position is $31,061,387 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-01 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 69,515 -2,778 -3.84 31,041 -5.29 0.1815
2026-01-28 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 72,293 -2,701 -3.60 32,775 11.59 0.1783
2025-11-03 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 74,994 -100 -0.13 29,371 -12.15 0.1565
2025-08-13 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 75,094 -443 -0.59 33,432 -8.71 0.1926
2025-05-01 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 75,537 930 1.25 36,622 21.89 0.2331
2025-02-06 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 74,607 673 0.91 30,044 -12.62 0.1836
2024-11-12 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 73,934 -950 -1.27 34,385 -2.03 0.2169
2024-08-05 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 74,884 937 1.27 35,100 13.55 0.2343
2024-05-07 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 73,947 1,334 1.84 30,911 4.62 0.2139
2024-01-24 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 72,613 -288 -0.40 29,546 16.55 0.2242
2023-11-07 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 72,901 -730 -0.99 25,351 -2.17 0.2154
2023-08-01 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 73,631 3,544 5.06 25,911 17.34 0.2103
2023-04-27 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 70,087 210 0.30 22,082 9.43 0.1982
2023-02-08 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 69,877 356 0.51 20,179 0.25 0.1949
2022-11-07 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 69,521 -321 -0.46 20,129 2.28 0.2082
2022-07-28 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 69,842 76 0.11 19,681 8.10 0.1910
2022-05-04 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 69,766 -1,286 -1.81 18,207 16.69 0.1467
2022-02-04 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 71,052 -1,136 -1.57 15,603 19.16 0.1189
2021-11-12 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 72,188 -646 -0.89 13,094 -10.84 0.1068
2021-08-02 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 72,834 -446 -0.61 14,686 -6.74 0.1194
2021-05-06 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 73,280 -1,867 -2.48 15,747 -11.33 0.1376
2021-01-28 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 75,147 -5,918 -7.30 17,760 -19.49 0.1611
2020-11-05 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 81,065 20,161 33.10 22,059 24.76 0.2193
2020-08-04 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 60,904 14,668 31.72 17,681 60.71 0.2494
2020-05-05 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 46,236 -2,050 -4.25 11,002 4.07 0.1891
2020-01-27 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 48,286 291 0.61 10,572 30.02 0.1273
2019-10-31 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 47,995 -717 -1.47 8,131 -8.98 0.0992
2019-07-25 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 48,712 -379 -0.77 8,933 -1.07 0.1034
2019-04-29 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 49,091 -3,417 -6.51 9,030 3.78 0.1074
2019-01-28 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 52,508 -10,834 -17.10 8,701 -28.73 0.1119
2018-10-29 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 63,342 710 1.13 12,209 14.69 0.1152
2018-08-07 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 62,632 -14,720 -19.03 10,645 -15.56 0.1071
2018-05-14 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 77,352 -1,100 -1.40 12,607 7.23 0.1272
2018-02-09 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 78,452 2,983 3.95 11,757 2.47 0.1145
2017-11-14 2017-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 75,469 13,669 22.12 11,474 44.07 0.1371
2017-08-02 2017-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 61,800 300 0.49 7,964 18.42 0.1103
2017-05-10 2017-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 61,500 200 0.33 6,725 48.91 0.0945
2017-02-10 2016-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 61,300 300 0.49 4,516 -15.11 0.0665
2016-11-01 2016-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 61,000 300 0.49 5,320 1.90 0.0808
2016-08-15 2016-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 60,700 -6,100 -9.13 5,221 -1.68 0.0733
2016-05-16 2016-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 66,800 1,400 2.14 5,310 -35.47 0.0691
2016-02-12 2015-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 65,400 -1,500 -2.24 8,229 18.11 0.1095
2015-11-20 2015-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 66,900 -400 -0.59 6,967 -12.86 0.0977
2015-02-11 2014-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 67,300 1,000 1.51 7,995 7.37 0.0942
2014-11-21 2014-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 66,300 -1,200 -1.78 7,446 16.53 0.0924
2014-08-07 2014-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 67,500 2,200 3.37 6,390 38.37 0.0773
2014-05-19 2014-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 65,300 -1,500 -2.25 4,618 -6.95 0.0585
2014-02-05 2013-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 66,800 -1,600 -2.34 4,963 -4.30 0.0611
2013-11-01 2013-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 68,400 -108,128 -61.25 5,186 -63.22 0.0664
2013-09-17 2013-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 176,528 11,800 7.16 14,099 55.69 0.1922
2013-09-17 2013-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 164,728 164,728 9,056 0.1297
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.