Vertex Pharmaceuticals Incorporated
US ˙ NasdaqGS ˙ US92532F1003

SecurityVRTX / Vertex Pharmaceuticals Incorporated
InstitutionSecurian Asset Management, Inc
Latest Disclosed Ownership6,899 shares
Latest Disclosed Value $ 3,080,679
Securian Asset Management, Inc ownership in VRTX / Vertex Pharmaceuticals Incorporated

On May 1, 2026 - Securian Asset Management, Inc filed a 13F-HR form disclosing ownership of 6,899 shares of Vertex Pharmaceuticals Incorporated (US:VRTX) valued at $3,080,679 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 4, 2026 disclosing 6,899 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of 0.00% during the quarter. The current value of the position is $2,955,118 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-01 2026-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,899 0 0.00 3,081 -1.50 0.1219
2026-02-04 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,899 -5,417 -43.98 3,128 -35.16 0.1186
2025-10-23 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 12,316 -1,126 -8.38 4,823 -19.40 0.1277
2025-07-30 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 13,442 -156 -1.15 5,984 -9.22 0.1706
2025-05-01 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 13,598 -211 -1.53 6,593 18.56 0.2003
2025-02-10 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 13,809 -435 -3.05 5,561 -16.06 0.1619
2024-11-13 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 14,244 -551 -3.72 6,625 -4.47 0.1912
2024-07-15 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 14,795 -384 -2.53 6,935 9.30 0.2024
2024-04-26 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 15,179 -1,145 -7.01 6,345 -4.49 0.1861
2024-02-08 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 16,324 -2,177 -11.77 6,642 3.25 0.1883
2023-10-30 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 18,501 -3,131 -14.47 6,434 -15.49 0.1922
2023-08-07 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 21,632 -270 -1.23 7,613 10.32 0.1955
2023-04-27 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 21,902 168 0.77 6,901 9.94 0.1839
2023-02-03 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 21,734 216 1.00 6,276 104,500.00 0.1755
2022-10-28 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 21,518 228 1.07 6 20.00 0.1858
2022-08-04 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 21,290 0 0.00 6 0.00 0.1437
2022-05-03 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 21,290 -233 -1.08 6 25.00 0.1085
2022-02-10 2021-12-31 13F VERTEX PHARMACEUTICA COM 92532F100 21,523 -891 -3.98 5 0.00 0.0872
2021-11-08 2021-09-30 13F VERTEX PHARMACEUTICA COM 92532F100 22,414 -205 -0.91 4 0.00 0.0836
2021-08-10 2021-06-30 13F VERTEX PHARMACEUTICA COM 92532F100 22,619 -267 -1.17 5 0.00 0.0927
2021-05-10 2021-03-31 13F VERTEX PHARMACEUTICA COM 92532F100 22,886 -782 -3.30 5 -20.00 0.1068
2021-02-08 2020-12-31 13F VERTEX PHARMACEUTICA COM 92532F100 23,668 -414 -1.72 6 -99.92 0.1265
2020-11-04 2020-09-30 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 24,082 -412 -1.68 6,553 -7.85 0.1589
2020-08-06 2020-06-30 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 24,494 -1,167 -4.55 7,111 16.46 0.1819
2020-05-07 2020-03-31 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 25,661 -409 -1.57 6,106 6.97 0.1723
2020-02-04 2019-12-31 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 26,070 -812 -3.02 5,708 25.34 0.1260
2019-11-12 2019-09-30 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 26,882 -140 -0.52 4,554 113,750.00 0.1044
2019-08-05 2019-06-30 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 27,022 336 1.26 5 0.00 0.1148
2019-04-26 2019-03-31 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 26,686 164 0.62 5 0.00 0.1171
2019-02-04 2018-12-31 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 26,522 173 0.66 4 -20.00 0.1180
2018-10-26 2018-09-30 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 26,349 65 0.25 5 25.00 0.1206
2018-08-09 2018-06-30 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 26,284 164 0.63 4 0.00 0.1107
2018-04-30 2018-03-31 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 26,120 200 0.77 4 33.33 0.1092
2018-02-05 2017-12-31 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 25,920 365 1.43 4 0.00 0.0960
2017-11-03 2017-09-30 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 25,555 369 1.47 4 0.00 0.1008
2017-08-14 2017-06-30 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 25,186 257 1.03 3 50.00 0.0855
2017-05-11 2017-03-31 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 24,929 44 0.18 3 100.00 0.0730
2017-02-10 2016-12-31 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 24,885 352 1.43 2 -50.00 0.0490
2016-11-14 2016-09-30 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 24,533 357 1.48 2 0.00 0.0579
2016-08-10 2016-06-30 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 24,176 214 0.89 2 100.00 0.0582
2016-11-08 2016-03-31 13F/A-1 Vertex Pharmaceuticals COMMON STOCK 92532F100 23,962 291 1.23 2 -50.00 0.0549
2016-05-09 2016-03-31 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 23,962 1,905
2016-11-08 2015-12-31 13F/A-1 Vertex Pharmaceuticals COMMON STOCK 92532F100 23,671 627 2.72 3 0.00 0.0885
2016-02-10 2015-12-31 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 23,671 2,979
2016-11-08 2015-09-30 13F/A-1 Vertex Pharmaceuticals COMMON STOCK 92532F100 23,044 -92 -0.40 2 0.00 0.0788
2015-11-12 2015-09-30 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 23,044 2,400
2016-11-08 2015-06-30 13F/A-2 Vertex Pharmaceuticals COMMON STOCK 92532F100 23,136 480 2.12 3 0.00 0.0892
2015-08-10 2015-06-30 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 23,136 2,857
2016-11-08 2015-03-31 13F/A-2 Vertex Pharmaceuticals COMMON STOCK 92532F100 22,656 819 3.75 3 0.00 0.0780
2015-04-27 2015-03-31 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 22,656 2,673
2016-11-08 2014-12-31 13F/A-2 Vertex Pharmaceuticals COMMON STOCK 92532F100 21,837 855 4.07 3 0.00 0.0803
2016-11-08 2014-09-30 13F/A-2 Vertex Pharmaceuticals COMMON STOCK 92532F100 20,982 9 0.04 2 100.00 0.0799
2014-10-28 2014-09-30 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 20,982 2,356
2016-11-08 2014-06-30 13F/A-2 Vertex Pharmaceuticals COMMON STOCK 92532F100 20,973 58 0.28 2 0.00 0.0673
2014-08-01 2014-06-30 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 20,973 1,986
2016-11-08 2014-03-31 13F/A-2 Vertex Pharmaceuticals COMMON STOCK 92532F100 20,915 174 0.84 1 0.00 0.0536
2014-05-07 2014-03-31 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 20,915 1,479,109
2016-11-08 2013-12-31 13F/A-2 Vertex Pharmaceuticals COMMON STOCK 92532F100 20,741 131 0.64 2 0.00 0.0582
2014-01-23 2013-12-31 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 20,741 1,541,056
2016-11-08 2013-09-30 13F/A-2 Vertex Pharmaceuticals COMMON STOCK 92532F100 20,610 -12,565 -37.87 2 -50.00 0.0628
2013-11-08 2013-09-30 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 20,610 1,563
2016-11-08 2013-06-30 13F/A-2 Vertex Pharmaceuticals COMMON STOCK 92532F100 33,175 367 1.12 3 100.00 0.1075
2013-08-13 2013-06-30 13F Vertex Pharmaceuticals COMMON STOCK 92532F100 33,175 2,650
2016-11-08 2013-03-31 13F/A-2 Vertex Pharmaceuticals COMMON STOCK 92532F100 32,808 0 0.00 2 0.00 0.0737
2016-11-08 2012-12-31 13F/A-2 Vertex Pharmaceuticals COMMON STOCK 92532F100 32,808 208 0.64 1 0.00 0.0613
2016-11-08 2012-09-30 13F/A-2 Vertex Pharmaceuticals COMMON STOCK 92532F100 32,600 1,046 3.31 2 0.00 0.0815
2016-11-08 2012-06-30 13F/A-2 Vertex Pharmaceuticals COMMON STOCK 92532F100 31,554 -255 -0.80 2 0.00 0.0829
2016-11-08 2012-03-31 13F/A-2 Vertex Pharmaceuticals COMMON STOCK 92532F100 31,809 100 0.32 1 0.00 0.0588
2016-11-08 2011-12-31 13F/A-2 Vertex Pharmaceuticals COMMON STOCK 92532F100 31,709 654 2.11 1 0.00 0.0537
2016-11-08 2011-09-30 13F/A-2 Vertex Pharmaceuticals COMMON STOCK 92532F100 31,055 31,055 1 0.0793
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.