Twist Bioscience Corporation
US ˙ NasdaqGS ˙ US90184D1000

SecurityTWST / Twist Bioscience Corporation
InstitutionSei Investments Co
Latest Disclosed Ownership270,099 shares
Latest Disclosed Value $ 8,567,569
Sei Investments Co reports 9.03% decrease in ownership of TWST / Twist Bioscience Corporation

On February 13, 2026 - Sei Investments Co filed a 13F-HR form disclosing ownership of 270,099 shares of Twist Bioscience Corporation (US:TWST) valued at $8,567,540 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 13, 2025 disclosing 296,918 shares of Twist Bioscience Corporation. This represents a change in shares of -9.03% during the quarter. The current value of the position is $19,536,261 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-02-13 2025-12-31 13F TWIST BIOSCIENCE COM 90184D100 270,099 -26,819 -9.03 8,568 2.54 0.0085
2025-11-13 2025-09-30 13F TWIST BIOSCIENCE COM 90184D100 296,918 13,681 4.83 8,355 -19.82 0.0090
2025-08-14 2025-06-30 13F TWIST BIOSCIENCE COM 90184D100 283,237 -31,914 -10.13 10,420 -15.78 0.0121
2025-05-14 2025-03-31 13F/A-1 TWIST BIOSCIENCE COM 90184D100 315,151 18,735 6.32 12,373 -10.17 0.0159
2025-05-13 2025-03-31 13F TWIST BIOSCIENCE COM 90184D100 300,143 3,727 13,917 0.0151
2025-02-11 2024-12-31 13F TWIST BIOSCIENCE COM 90184D100 296,416 -13,346 -4.31 13,774 -1.58 0.0177
2024-11-12 2024-09-30 13F TWIST BIOSCIENCE COM 90184D100 309,762 -4,896 -1.56 13,995 -9.74 0.0182
2024-08-13 2024-06-30 13F TWIST BIOSCIENCE COM 90184D100 314,658 91,103 40.75 15,507 102.16 0.0220
2024-05-07 2024-03-31 13F TWIST BIOSCIENCE COM 90184D100 223,555 55,124 32.73 7,670 23.55 0.0112
2024-02-14 2023-12-31 13F TWIST BIOSCIENCE COM 90184D100 168,431 128,260 319.29 6,208 663.59 0.0100
2023-11-14 2023-09-30 13F TWIST BIOSCIENCE COM 90184D100 40,171 -9,012 -18.32 814 -19.18 0.0015
2023-08-11 2023-06-30 13F TWIST BIOSCIENCE COM 90184D100 49,183 37,945 337.65 1,006 495.27 0.0018
2023-05-12 2023-03-31 13F TWIST BIOSCIENCE COM 90184D100 11,238 -239,975 -95.53 169 -97.17 0.0003
2023-02-10 2022-12-31 13F TWIST BIOSCIENCE COM 90184D100 251,213 -8,727 -3.36 5,981 -34.71 0.0133
2022-11-14 2022-09-30 13F TWIST BIOSCIENCE COM 90184D100 259,940 -176,961 -40.50 9,160 -40.03 0.0204
2022-08-15 2022-06-30 13F TWIST BIOSCIENCE COM 90184D100 436,901 -11,326 -2.53 15,274 -30.99 0.0330
2022-05-13 2022-03-31 13F TWIST BIOSCIENCE COM 90184D100 448,227 117,980 35.72 22,133 -13.40 0.0445
2022-02-14 2021-12-31 13F TWIST BIOSCIENCE COM 90184D100 330,247 70,838 27.31 25,558 -7.90 0.0479
2021-11-12 2021-09-30 13F TWIST BIOSCIENCE COM 90184D100 259,409 34,746 15.47 27,749 -7.31 0.0582
2021-08-06 2021-06-30 13F TWIST BIOSCIENCE COM 90184D100 224,663 2,306 1.04 29,936 8.22 0.0664
2021-05-12 2021-03-31 13F TWIST BIOSCIENCE COM 90184D100 222,357 211,002 1,858.23 27,661 1,624.50 0.0697
2021-02-08 2020-12-31 13F TWIST BIOSCIENCE COM 90184D100 11,355 -2,241 -16.48 1,604 55.28 0.0041
2020-12-04 2020-09-30 13F/A-1 TWIST BIOSCIENCE COM 90184D100 13,596 13,596 1,033 0.0030
2020-11-06 2020-09-30 13F TWIST BIOSCIENCE COM 90184D100 13,596 13,596 1,033
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.