Schrödinger, Inc.
US ˙ NasdaqGS ˙ US80810D1037

SecuritySDGR / Schrödinger, Inc.
InstitutionState Street Corp
Latest Disclosed Ownership2,191,427 shares
Latest Disclosed Value $ 24,894,611
State Street Corp reports 2.79% increase in ownership of SDGR / Schrödinger, Inc.

On May 15, 2026 - State Street Corp filed a 13F-HR form disclosing ownership of 2,191,427 shares of Schrödinger, Inc. (US:SDGR) valued at $24,894,611 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 2,131,906 shares of Schrödinger, Inc.. This represents a change in shares of 2.79% during the quarter. The current value of the position is $34,734,118 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F SCHRODINGER COM 80810D103 2,191,427 59,521 2.79 24,895 -34.69 0.0009
2026-02-13 2025-12-31 13F SCHRODINGER COM 80810D103 2,131,906 -73,128 -3.32 38,118 -13.82 0.0013
2025-11-14 2025-09-30 13F SCHRODINGER COM 80810D103 2,205,034 19,278 0.88 44,233 0.58 0.0015
2025-08-14 2025-06-30 13F SCHRODINGER COM 80810D103 2,185,756 -26,188 -1.18 43,977 0.72 0.0016
2025-05-15 2025-03-31 13F SCHRODINGER COM 80810D103 2,211,944 -104,657 -4.52 43,664 -2.29 0.0018
2025-02-14 2024-12-31 13F SCHRODINGER COM 80810D103 2,316,601 160,981 7.47 44,687 11.76 0.0018
2024-11-14 2024-09-30 13F SCHRODINGER COM 80810D103 2,155,620 38,972 1.84 39,987 -2.32 0.0016
2024-08-14 2024-06-30 13F SCHRODINGER COM 80810D103 2,116,648 7,815 0.37 40,936 -28.11 0.0018
2024-05-15 2024-03-31 13F SCHRODINGER COM 80810D103 2,108,833 53,489 2.60 56,938 -22.62 0.0025
2024-02-14 2023-12-31 13F SCHRODINGER COM 80810D103 2,055,344 27,577 1.36 73,581 28.36 0.0036
2023-11-14 2023-09-30 13F SCHRODINGER COM 80810D103 2,027,767 33,647 1.69 57,325 -42.41 0.0032
2023-08-14 2023-06-30 13F SCHRODINGER COM 80810D103 1,994,120 803,310 67.46 99,546 217.49 0.0052
2023-05-15 2023-03-31 13F SCHRODINGER COM 80810D103 1,190,810 50,698 4.45 31,354 47.15 0.0018
2023-05-15 2022-12-31 13F/A-99 SCHRODINGER COM 80810D103 1,140,112 79,505 7.50 21,309 -19.57 0.0013
2023-05-15 2022-12-31 13F SCHRODINGER COM 80810D103 1,140,112 79,505 21,309 0.0013
2022-11-15 2022-09-30 13F SCHRODINGER COM 80810D103 1,060,607 70,222 7.09 26,494 1.29 0.0017
2022-08-15 2022-06-30 13F SCHRODINGER COM 80810D103 990,385 67,036 7.26 26,156 -16.98 0.0016
2022-05-16 2022-03-31 13F SCHRODINGER COM 80810D103 923,349 32,595 3.66 31,505 1.55 0.0016
2022-02-14 2021-12-31 13F SCHRODINGER COM 80810D103 890,754 12,948 1.48 31,025 -35.36 0.0015
2021-11-15 2021-09-30 13F SCHRODINGER COM 80810D103 877,806 45,400 5.45 47,998 -23.74 0.0025
2021-08-16 2021-06-30 13F SCHRODINGER COM 80810D103 832,406 244,873 41.68 62,938 40.41 0.0033
2021-07-09 2021-03-31 13F/A-1 SCHRODINGER COM 80810D103 587,533 -8,892 -1.49 44,823 -5.09 0.0026
2021-05-17 2021-03-31 13F SCHRODINGER COM 80810D103 587,533 -8,892 44,823 0.0026
2021-02-16 2020-12-31 13F SCHRODINGER COM 80810D103 596,425 80,206 15.54 47,225 92.55 0.0029
2020-11-10 2020-09-30 13F SCHRODINGER COM 80810D103 516,219 239,188 86.34 24,526 -3.32 0.0017
2020-08-14 2020-06-30 13F SCHRODINGER COM 80810D103 277,031 31,466 12.81 25,368 139.57 0.0018
2020-06-19 2020-03-31 13F/A-1 SCHRODINGER COM 80810D103 245,565 245,565 10,589 0.0009
2020-05-11 2020-03-31 13F SCHRODINGER COM 80810D103 245,565 10,589 0.0009
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.