Pyxis Oncology, Inc.
US ˙ NasdaqGS ˙ US7473241013

SecurityPYXS / Pyxis Oncology, Inc.
InstitutionState Street Corp
Latest Disclosed Ownership248,837 shares
Latest Disclosed Value $ 363,302
State Street Corp reports 2.98% increase in ownership of PYXS / Pyxis Oncology, Inc.

On May 15, 2026 - State Street Corp filed a 13F-HR form disclosing ownership of 248,837 shares of Pyxis Oncology, Inc. (US:PYXS) valued at $363,302 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 241,637 shares of Pyxis Oncology, Inc.. This represents a change in shares of 2.98% during the quarter. The current value of the position is $425,511 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F PYXIS ONCOLOGY COMMON STOCK 747324101 248,837 7,200 2.98 363 31.05 0.0000
2026-02-13 2025-12-31 13F PYXIS ONCOLOGY COMMON STOCK 747324101 241,637 39,582 19.59 278 -38.17 0.0000
2025-11-14 2025-09-30 13F PYXIS ONCOLOGY COMMON STOCK 747324101 202,055 16,000 8.60 449 119.61 0.0000
2025-08-14 2025-06-30 13F PYXIS ONCOLOGY COMMON STOCK 747324101 186,055 -746,143 -80.04 205 -77.66 0.0000
2025-05-15 2025-03-31 13F PYXIS ONCOLOGY COMMON STOCK 747324101 932,198 -11,970 -1.27 913 -37.98 0.0000
2025-02-14 2024-12-31 13F PYXIS ONCOLOGY COMMON STOCK 747324101 944,168 -7,083 -0.74 1,473 -57.83 0.0001
2024-11-14 2024-09-30 13F PYXIS ONCOLOGY COMMON STOCK 747324101 951,251 208,344 28.04 3,491 41.97 0.0001
2024-08-14 2024-06-30 13F PYXIS ONCOLOGY COMMON STOCK 747324101 742,907 633,552 579.35 2,459 428.82 0.0001
2024-05-15 2024-03-31 13F PYXIS ONCOLOGY COMMON STOCK 747324101 109,355 26,300 31.67 466 212.08 0.0000
2024-02-14 2023-12-31 13F PYXIS ONCOLOGY COMMON STOCK 747324101 83,055 0 0.00 149 -9.70 0.0000
2023-11-14 2023-09-30 13F PYXIS ONCOLOGY COMMON STOCK 747324101 83,055 9,366 12.71 165 -12.23 0.0000
2023-08-14 2023-06-30 13F PYXIS ONCOLOGY COMMON STOCK 747324101 73,689 11,400 18.30 189 -24.50 0.0000
2023-05-15 2023-03-31 13F PYXIS ONCOLOGY COMMON STOCK 747324101 62,289 0 0.00 250 200.00 0.0000
2023-05-15 2022-12-31 13F/A-99 PYXIS ONCOLOGY COMMON STOCK 747324101 62,289 31,300 101.00 83 36.07 0.0000
2023-05-15 2022-12-31 13F PYXIS ONCOLOGY COMMON STOCK 747324101 62,289 31,300 83 0.0000
2022-11-15 2022-09-30 13F PYXIS ONCOLOGY COMMON STOCK 747324101 30,989 0 0.00 61 -17.57 0.0000
2022-08-15 2022-06-30 13F PYXIS ONCOLOGY COMMON STOCK 747324101 30,989 -113,806 -78.60 74 -87.35 0.0000
2022-05-16 2022-03-31 13F PYXIS ONCOLOGY COMMON STOCK 747324101 144,795 51,920 55.90 585 -42.59 0.0000
2022-02-14 2021-12-31 13F PYXIS ONCOLOGY COMMON STOCK 747324101 92,875 92,875 1,019 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.