Prothena Corporation plc
US ˙ NasdaqGS ˙ IE00B91XRN20

SecurityPRTA / Prothena Corporation plc
InstitutionTrexquant Investment LP
Latest Disclosed Ownership24,543 shares
Latest Disclosed Value $ 238,558
Trexquant Investment LP reports 26.61% increase in ownership of PRTA / Prothena Corporation plc

On May 15, 2026 - Trexquant Investment LP filed a 13F-HR form disclosing ownership of 24,543 shares of Prothena Corporation plc (US:PRTA) valued at $238,558 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 19,384 shares of Prothena Corporation plc. This represents a change in shares of 26.61% during the quarter. The current value of the position is $215,733 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F PROTHENA CORP SHS G72800108 24,543 5,159 26.61 239 28.65 0.0017
2026-02-17 2025-12-31 13F PROTHENA CORP SHS G72800108 19,384 -259,595 -93.05 185 -93.20 0.0017
2025-11-14 2025-09-30 13F PROTHENA CORP SHS G72800108 278,979 -273,847 -49.54 2,723 -18.87 0.0280
2025-08-12 2025-06-30 13F PROTHENA CORP SHS G72800108 552,826 552,826 3,356 0.0378
2024-05-14 2024-03-31 13F PROTHENA CORP SHS G72800108 0 -67,683 -100.00 0 -100.00
2024-02-09 2023-12-31 13F PROTHENA CORP SHS G72800108 67,683 10,840 19.07 2,460 -10.32 0.0553
2023-11-13 2023-09-30 13F PROTHENA CORP SHS G72800108 56,843 56,843 2,743 0.0688
2023-08-11 2023-06-30 13F PROTHENA CORP SHS G72800108 0 -42,200 -100.00 0 -100.00
2023-05-15 2023-03-31 13F PROTHENA CORP SHS G72800108 42,200 10,963 35.10 2,045 8.66 0.0562
2023-02-13 2022-12-31 13F PROTHENA CORP SHS G72800108 31,237 31,237 1,882 0.0534
2022-05-13 2022-03-31 13F PROTHENA CORP SHS G72800108 0 -5,866 -100.00 0 -100.00
2022-02-14 2021-12-31 13F PROTHENA CORP SHS G72800108 5,866 5,866 290 0.0179
2021-11-12 2021-09-30 13F PROTHENA CORP SHS G72800108 0 -7,326 -100.00 0 -100.00
2021-08-12 2021-06-30 13F PROTHENA CORP SHS G72800108 7,326 7,326 377 0.0318
2021-02-11 2020-12-31 13F PROTHENA CORP SHS G72800108 0 -47,039 -100.00 0 -100.00
2020-11-06 2020-09-30 13F PROTHENA CORP SHS G72800108 47,039 -7,102 -13.12 470 -16.96 0.0302
2020-08-07 2020-06-30 13F PROTHENA CORP SHS G72800108 54,141 54,141 15.10 566 20.43 0.0393
2019-05-13 2019-03-31 13F PROTHENA CORP SHS G72800108 0 -19,657 -100.00 0 -100.00
2019-02-13 2018-12-31 13F PROTHENA CORP SHS G72800108 19,657 -3,342 -14.53 202 -32.89 0.0126
2018-11-09 2018-09-30 13F PROTHENA CORP SHS G72800108 22,999 22,999 17.00 301 49.01 0.0226
2018-08-07 2018-06-30 13F PROTHENA CORP SHS G72800108 0 -26,465 -100.00 0 -100.00
2018-05-03 2018-03-31 13F PROTHENA CORP SHS G72800108 26,465 26,465 972 0.0678
2017-05-08 2017-03-31 13F PROTHENA CORP SHS G72800108 0 -7,613 -100.00 0 -100.00
2017-02-10 2016-12-31 13F PROTHENA CORP SHS G72800108 7,613 3,400 80.70 374 47.83 0.0592
2016-11-10 2016-09-30 13F PROTHENA CORP SHS G72800108 4,213 -16,206 -79.37 253 -64.57 0.0565
2016-08-10 2016-06-30 13F PROTHENA CORP SHS G72800108 20,419 13,124 179.90 714 138.00 0.0938
2016-05-11 2016-03-31 13F PROTHENA CORP SHS G72800108 7,295 7,295 -64.27 300 -57.98 0.0351
2015-05-13 2015-03-31 13F PROTHENA CORP SHS G72800108 0 -19,636 -100.00 0 -100.00
2015-02-13 2014-12-31 13F PROTHENA CORP SHS G72800108 19,636 19,636 407 0.0720
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.