Penumbra, Inc.
US ˙ NYSE ˙ US70975L1070

SecurityPEN / Penumbra, Inc.
InstitutionWetherby Asset Management Inc
Latest Disclosed Ownership25,525 shares
Latest Disclosed Value $ 6,465,993
Wetherby Asset Management Inc reports 1.33% decrease in ownership of PEN / Penumbra, Inc.

On November 14, 2025 - Wetherby Asset Management Inc filed a 13F-HR form disclosing ownership of 25,525 shares of Penumbra, Inc. (US:PEN) valued at $6,465,993 USD as of September 30, 2025. The entity filed a previous 13F-HR on August 14, 2025 disclosing 25,868 shares of Penumbra, Inc.. This represents a change in shares of -1.33% during the quarter. The current value of the position is $8,181,528 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2025-11-14 2025-09-30 13F PENUMBRA COM 70975L107 25,525 -343 -1.33 6,466 -2.61 0.1926
2025-08-14 2025-06-30 13F PENUMBRA COM 70975L107 25,868 -709 -2.67 6,639 5.18 0.2955
2025-02-14 2024-12-31 13F PENUMBRA COM 70975L107 26,577 -207 -0.77 6,312 21.27 0.3026
2024-11-14 2024-09-30 13F PENUMBRA COM 70975L107 26,784 -23 -0.09 5,204 7.88 0.2380
2024-08-14 2024-06-30 13F PENUMBRA COM 70975L107 26,807 -32 -0.12 4,824 -19.45 0.2274
2024-05-15 2024-03-31 13F PENUMBRA COM 70975L107 26,839 3 0.01 5,990 -11.27 0.2854
2024-02-14 2023-12-31 13F PENUMBRA COM 70975L107 26,836 -260 -0.96 6,750 2.99 0.3516
2023-11-14 2023-09-30 13F PENUMBRA COM 70975L107 27,096 265 0.99 6,555 -29.00 0.3717
2023-08-14 2023-06-30 13F PENUMBRA COM 70975L107 26,831 -1,450 -5.13 9,231 17.13 0.4971
2023-05-12 2023-03-31 13F PENUMBRA COM 70975L107 28,281 92 0.33 7,882 25.69 0.4612
2023-02-14 2022-12-31 13F PENUMBRA COM 70975L107 28,189 1 0.00 6,271 17.33 0.4028
2022-11-14 2022-09-30 13F PENUMBRA COM 70975L107 28,188 -577 -2.01 5,344 49.19 0.3768
2022-08-15 2022-06-30 13F PENUMBRA COM 70975L107 28,765 -72,417 -71.57 3,582 -84.06 0.2445
2022-05-16 2022-03-31 13F PENUMBRA COM 70975L107 101,182 -65 -0.06 22,476 -22.74 1.2879
2022-02-14 2021-12-31 13F PENUMBRA COM 70975L107 101,247 -8 -0.01 29,090 7.80 1.6334
2021-11-15 2021-09-30 13F PENUMBRA COM 70975L107 101,255 -15 -0.01 26,984 -2.77 1.6651
2021-08-16 2021-06-30 13F PENUMBRA COM 70975L107 101,270 81,270 406.35 27,754 412.82 1.6934
2021-05-14 2021-03-31 13F PENUMBRA COM 70975L107 20,000 -86,504 -81.22 5,412 -70.96 0.4125
2021-02-11 2020-12-31 13F PENUMBRA COM 70975L107 106,504 104,750 5,972.06 18,638 5,365.69 1.2639
2020-12-16 2020-09-30 13F/A-01 PENUMBRA COM 70975L107 23,232 -17,210 4,516 0.4140
2020-12-16 2020-09-30 13F/A-02 PENUMBRA COM 70975L107 1,754 -38,688 -95.66 341 -95.28 1.0246
2020-11-13 2020-09-30 13F PENUMBRA COM 70975L107 106,928 66,486 20,785 1,322,108.5039
2020-08-14 2020-06-30 13F PENUMBRA COM 70975L107 40,442 7,994 24.64 7,232 38.17 0.6855
2020-05-06 2020-03-31 13F PENUMBRA COM 70975L107 32,448 7,572 30.44 5,234 28.10 0.5875
2020-01-28 2019-12-31 13F PENUMBRA COM 70975L107 24,876 -492 -1.94 4,086 19.75 0.4024
2019-10-31 2019-09-30 13F PENUMBRA COM 70975L107 25,368 7,352 40.81 3,412 18.35 0.3562
2019-07-25 2019-06-30 13F PENUMBRA COM 70975L107 18,016 33 0.18 2,883 9.04 0.3156
2019-07-25 2019-03-31 13F/A-1 PENUMBRA COM 70975L107 17,983 -1,000 -5.27 2,644 13.97 0.3293
2019-05-09 2019-03-31 13F PENUMBRA COM 70975L107 17,983 -1,000 2,644
2019-01-30 2018-12-31 13F PENUMBRA COM 70975L107 18,983 -1,144 -5.68 2,320 -23.00 0.3282
2018-11-07 2018-09-30 13F PENUMBRA COM 70975L107 20,127 -925 -4.39 3,013 3.61 0.3722
2018-07-24 2018-06-30 13F PENUMBRA COM 70975L107 21,052 -2,515 -10.67 2,908 6.68 0.3937
2018-05-04 2018-03-31 13F PENUMBRA COM 70975L107 23,567 -1,500 -5.98 2,726 15.56 0.3763
2018-02-09 2017-12-31 13F PENUMBRA COM 70975L107 25,067 -3,000 -10.69 2,359 -6.91 0.3273
2017-11-13 2017-09-30 13F PENUMBRA COM 70975L107 28,067 5,000 21.68 2,534 25.20 0.3769
2017-08-01 2017-06-30 13F PENUMBRA COM 70975L107 23,067 -2,000 -7.98 2,024 -3.25 0.3443
2017-04-27 2017-03-31 13F PENUMBRA COM 70975L107 25,067 -7,000 -21.83 2,092 2.25 0.3762
2017-02-08 2016-12-31 13F PENUMBRA COM 70975L107 32,067 10,000 45.32 2,046 22.00 0.4007
2016-11-14 2016-09-30 13F PENUMBRA COM 70975L107 22,067 0 0.00 1,677 27.72 0.3393
2016-08-10 2016-06-30 13F PENUMBRA COM 70975L107 22,067 22,067 1,313 0.2911
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.