Pacific Biosciences of California, Inc.
US ˙ NasdaqGS ˙ US69404D1081

SecurityPACB / Pacific Biosciences of California, Inc.
InstitutionState Street Corp
Latest Disclosed Ownership6,121,716 shares
Latest Disclosed Value $ 8,080,665
State Street Corp reports 3.54% increase in ownership of PACB / Pacific Biosciences of California, Inc.

On May 15, 2026 - State Street Corp filed a 13F-HR form disclosing ownership of 6,121,716 shares of Pacific Biosciences of California, Inc. (US:PACB) valued at $8,080,665 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 5,912,223 shares of Pacific Biosciences of California, Inc.. This represents a change in shares of 3.54% during the quarter. The current value of the position is $9,978,397 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 6,121,716 209,493 3.54 8,081 -26.91 0.0003
2026-02-13 2025-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 5,912,223 2,579 0.04 11,056 46.15 0.0004
2025-11-14 2025-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 5,909,644 155,061 2.69 7,564 6.01 0.0003
2025-08-14 2025-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 5,754,583 -625,009 -9.80 7,136 -5.21 0.0003
2025-05-15 2025-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 6,379,592 -47,383 -0.74 7,528 -36.00 0.0003
2025-02-14 2024-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 6,426,975 150,819 2.40 11,761 10.24 0.0005
2024-11-14 2024-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 6,276,156 340,766 5.74 10,669 31.21 0.0004
2024-08-14 2024-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 5,935,390 166,503 2.89 8,131 -62.41 0.0004
2024-05-15 2024-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 5,768,887 144,558 2.57 21,633 -60.79 0.0010
2024-02-14 2023-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 5,624,329 252,447 4.70 55,175 23.01 0.0027
2023-11-14 2023-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 5,371,882 43,231 0.81 44,855 -36.71 0.0025
2023-08-14 2023-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 5,328,651 -34,168 -0.64 70,871 14.13 0.0037
2023-05-15 2023-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 5,362,819 135,323 2.59 62,098 45.22 0.0035
2023-05-15 2022-12-31 13F/A-99 PACIFIC BIOSCIENCES CALIF IN COM 69404D108 5,227,496 176,143 3.49 42,761 45.82 0.0025
2023-05-15 2022-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 5,227,496 176,143 42,761 0.0025
2022-11-15 2022-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 5,051,353 710,784 16.38 29,323 52.84 0.0019
2022-08-15 2022-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 4,340,569 -88,396 -2.00 19,185 -52.40 0.0011
2022-05-16 2022-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 4,428,965 271,315 6.53 40,304 -52.62 0.0020
2022-02-14 2021-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 4,157,650 -112,957 -2.64 85,066 -22.04 0.0040
2021-11-15 2021-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 4,270,607 17,032 0.40 109,114 -26.65 0.0058
2021-08-16 2021-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 4,253,575 222,602 5.52 148,748 10.78 0.0078
2021-07-09 2021-03-31 13F/A-1 PACIFIC BIOSCIENCES CALIF IN COM 69404D108 4,030,973 6,283 0.16 134,272 28.61 0.0077
2021-05-17 2021-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 4,030,973 6,283 134,272 0.0077
2021-02-16 2020-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 4,024,690 -308,296 -7.12 104,400 144.11 0.0064
2020-11-10 2020-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 4,332,986 91,157 2.15 42,767 192.24 0.0029
2020-08-14 2020-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 4,241,829 659,610 18.41 14,634 33.50 0.0011
2020-06-19 2020-03-31 13F/A-1 PACIFIC BIOSCIENCES CALIF IN COM 69404D108 3,582,219 340,259 10.50 10,962 -34.22 0.0010
2020-05-11 2020-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 3,582,219 340,259 10,962 962.6843
2020-02-06 2019-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 3,241,960 259,950 8.72 16,664 8.30 0.0011
2019-11-14 2019-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,982,010 72,788 2.50 15,387 -12.58 0.0011
2019-08-14 2019-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,909,222 150,186 5.44 17,601 -11.77 0.0013
2019-05-15 2019-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,759,036 156,705 6.02 19,948 3.59 0.0016
2019-02-12 2018-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 2,602,331 219,621 9.22 19,257 49.36 0.0018
2018-11-09 2018-09-30 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 2,382,710 135,369 6.02 12,893 61.61 0.0010
2018-08-14 2018-06-30 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 2,247,341 354,804 18.75 7,978 105.46 0.0007
2018-05-15 2018-03-31 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 1,892,537 84,603 4.68 3,883 -18.63 0.0003
2018-02-14 2017-12-31 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 1,807,934 169,788 10.36 4,772 -44.52 0.0004
2017-11-14 2017-09-30 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 1,638,146 116,901 7.68 8,601 58.72 0.0007
2017-08-14 2017-06-30 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 1,521,245 106,607 7.54 5,419 -25.92 0.0005
2017-05-15 2017-03-31 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 1,414,638 28,504 2.06 7,315 38.80 0.0007
2017-02-09 2016-12-31 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 1,386,134 68,226 5.18 5,270 -55.38 0.0005
2017-01-13 2016-09-30 13F/A-1 PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 1,317,908 -681 -0.05 11,810 27.32 0.0012
2016-11-14 2016-09-30 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 1,317,908 11,810
2016-08-12 2016-06-30 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 1,318,589 245,925 22.93 9,276 1.73 0.0010
2016-05-20 2016-03-31 13F/A-1 PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 1,072,664 135,746 14.49 9,118 -25.88 0.0010
2016-05-12 2016-03-31 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 1,072,664 9,118
2016-02-16 2015-12-31 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 936,918 115,597 14.07 12,301 309.21 0.0013
2015-11-16 2015-09-30 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 821,321 16,504 2.05 3,006 -35.19 0.0003
2015-08-13 2015-06-30 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 804,817 807 0.10 4,638 -1.17 0.0005
2015-05-15 2015-03-31 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 804,010 28,941 3.73 4,693 -22.76 0.0005
2015-02-11 2014-12-31 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 775,069 -9,610 -1.22 6,076 57.61 0.0006
2014-11-12 2014-09-30 13F/A-1 PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 784,679 62,213 8.61 3,855 -13.66 0.0004
2014-11-10 2014-09-30 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 784,679 3,855
2014-08-12 2014-06-30 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 722,466 41,661 6.12 4,465 22.50 0.0005
2014-05-15 2014-03-31 13F/A-1 PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 680,805 45,260 7.12 3,645 9.62 0.0004
2014-05-13 2014-03-31 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 681,005 3,646
2014-02-06 2013-12-31 13F/A-1 PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 635,545 89,710 16.44 3,325 10.10 0.0004
2014-02-06 2013-12-31 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 540,093 916
2013-11-12 2013-09-30 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 545,835 5,546 1.03 3,020 121.57 0.0004
2013-08-08 2013-06-30 13F PACIFIC BIOSCIENCES OF CALIF Common equity shares 69404D108 540,289 540,289 1,363 0.0002
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.