OPKO Health, Inc.
US ˙ NasdaqGS ˙ US68375N1037

SecurityOPK / OPKO Health, Inc.
InstitutionShell Asset Management Co
Latest Disclosed Ownership16,596 shares
Latest Disclosed Value $ 26
Shell Asset Management Co reports 55.18% decrease in ownership of OPK / OPKO Health, Inc.

On November 7, 2025 - Shell Asset Management Co filed a 13F-HR form disclosing ownership of 16,596 shares of OPKO Health, Inc. (US:OPK) valued at $25,724 USD as of September 30, 2025. The entity filed a previous 13F-HR on July 23, 2025 disclosing 37,028 shares of OPKO Health, Inc.. The current value of the position is $24,230 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2025-11-07 2025-09-30 13F OPKO HEALTH COM 68375N103 16,596 -20,432 -55.18 0 0.0026
2025-07-23 2025-06-30 13F OPKO HEALTH COM 68375N103 37,028 -3,969 -9.68 0 0.0017
2025-05-14 2025-03-31 13F OPKO HEALTH COM 68375N103 40,997 600 1.49 0 0.0032
2025-02-14 2024-12-31 13F OPKO HEALTH COM 68375N103 40,397 -460 -1.13 0 0.0026
2024-11-07 2024-09-30 13F OPKO HEALTH COM 68375N103 40,857 -2,428 -5.61 0 0.0027
2024-07-25 2024-03-31 13F OPKO HEALTH COM 68375N103 43,285 -5,656 -11.56 0 0.0025
2024-02-14 2023-12-31 13F OPKO HEALTH COM 68375N103 48,941 -14,773 -23.19 0 0.0034
2023-11-08 2023-09-30 13F OPKO HEALTH COM 68375N103 63,714 -999 -1.54 0 0.0042
2023-07-28 2023-06-30 13F OPKO HEALTH COM 68375N103 64,713 -370 -0.57 0 0.0055
2023-05-15 2023-03-31 13F OPKO HEALTH COM 68375N103 65,083 -228 -0.35 0 0.0039
2023-02-07 2022-12-31 13F OPKO HEALTH COM 68375N103 65,311 -13,265 -16.88 0 -100.00 0.0036
2022-11-14 2022-09-30 13F OPKO HEALTH COM 68375N103 78,576 29,030 58.59 149 19.20 0.0058
2022-08-09 2022-06-30 13F OPKO HEALTH COM 68375N103 49,546 86 0.17 125 -26.47 0.0037
2022-05-04 2022-03-31 13F OPKO HEALTH COM 68375N103 49,460 -7,318 -12.89 170 -37.73 0.0040
2022-02-09 2021-12-31 13F OPKO HEALTH COM 68375N103 56,778 268 0.47 273 32.52 0.0056
2021-11-04 2021-09-30 13F OPKO HEALTH COM 68375N103 56,510 -2,430 -4.12 206 -13.81 0.0046
2021-08-12 2021-06-30 13F OPKO HEALTH COM 68375N103 58,940 3,190 5.72 239 0.00 0.0046
2021-05-10 2021-03-31 13F OPKO HEALTH COM 68375N103 55,750 40,056 255.23 239 285.48 0.0048
2021-02-16 2020-12-31 13F OPKO HEALTH COM 68375N103 15,694 0 0.00 62 6.90 0.0013
2020-11-13 2020-09-30 13F OPKO HEALTH COM 68375N103 15,694 0 0.00 58 7.41 0.0013
2020-08-10 2020-06-30 13F OPKO HEALTH COM 68375N103 15,694 15,694 0.00 54 -6.90 0.0013
2017-10-20 2017-09-30 13F/A-1 OPKO HEALTH COM 68375N103 0 -68,822 -100.00 0 -100.00
2017-07-26 2017-06-30 13F OPKO HEALTH COM 68375N103 68,822 0 0.00 453 -17.79 0.0112
2017-04-26 2017-03-31 13F OPKO HEALTH COM 68375N103 68,822 68,822 551 0.0141
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.