Olema Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US68062P1066

SecurityOLMA / Olema Pharmaceuticals, Inc.
InstitutionD. E. Shaw & Co., Inc.
ManagerDE Shaw
Latest Disclosed Ownership39,230 shares
Latest Disclosed Value $ 584,920
D. E. Shaw & Co., Inc. reports 294.11% increase in ownership of OLMA / Olema Pharmaceuticals, Inc.

On May 15, 2026 - D. E. Shaw & Co., Inc. filed a 13F-HR form disclosing ownership of 39,230 shares of Olema Pharmaceuticals, Inc. (US:OLMA) valued at $584,919 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 9,954 shares of Olema Pharmaceuticals, Inc.. This represents a change in shares of 294.11% during the quarter. The current value of the position is $412,307 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F OLEMA PHARMACEUTICALS COM 68062P106 39,230 29,276 294.11 585 135.48 0.0004
2026-02-17 2025-12-31 13F OLEMA PHARMACEUTICALS COM 68062P106 9,954 9,954 249 0.0001
2025-05-15 2025-03-31 13F OLEMA PHARMACEUTICALS COM 68062P106 0 -12,445 -100.00 0 -100.00
2025-02-14 2024-12-31 13F OLEMA PHARMACEUTICALS COM 68062P106 12,445 -13,148 -51.37 73 -76.39 0.0001
2024-11-14 2024-09-30 13F OLEMA PHARMACEUTICALS COM 68062P106 25,593 4,534 21.53 306 34.36 0.0003
2024-08-14 2024-06-30 13F OLEMA PHARMACEUTICALS COM 68062P106 21,059 10,959 108.50 228 99.12 0.0002
2024-05-15 2024-03-31 13F OLEMA PHARMACEUTICALS COM 68062P106 10,100 -1,789 -15.05 114 -31.33 0.0001
2024-02-14 2023-12-31 13F OLEMA PHARMACEUTICALS COM 68062P106 11,889 11,889 167 0.0001
2022-11-14 2022-09-30 13F OLEMA PHARMACEUTICALS COM 68062P106 0 -154,081 -100.00 0 -100.00
2022-08-15 2022-06-30 13F OLEMA PHARMACEUTICALS COM 68062P106 154,081 -58,289 -27.45 627 -30.72 0.0007
2022-05-16 2022-03-31 13F OLEMA PHARMACEUTICALS COM 68062P106 212,370 124,288 141.10 905 9.83 0.0008
2022-02-14 2021-12-31 13F OLEMA PHARMACEUTICALS COM 68062P106 88,082 20,656 30.64 824 -55.65 0.0007
2021-11-15 2021-09-30 13F OLEMA PHARMACEUTICALS COM 68062P106 67,426 26,622 65.24 1,858 62.70 0.0017
2021-08-16 2021-06-30 13F OLEMA PHARMACEUTICALS COM 68062P106 40,804 -75,725 -64.98 1,142 -70.46 0.0010
2021-05-17 2021-03-31 13F OLEMA PHARMACEUTICALS COM 68062P106 116,529 116,529 3,866 0.0037
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.