Natera, Inc.
US ˙ NasdaqGS ˙ US6323071042

SecurityNTRA / Natera, Inc.
InstitutionState Street Corp
Latest Disclosed Ownership3,417,472 shares
Latest Disclosed Value $ 683,460,225
State Street Corp reports 5.94% increase in ownership of NTRA / Natera, Inc.

On May 15, 2026 - State Street Corp filed a 13F-HR form disclosing ownership of 3,417,472 shares of Natera, Inc. (US:NTRA) valued at $683,460,225 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 3,225,879 shares of Natera, Inc.. This represents a change in shares of 5.94% during the quarter. The current value of the position is $759,020,531 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F NATERA COM 632307104 3,417,472 191,593 5.94 683,460 -7.52 0.0236
2026-02-13 2025-12-31 13F NATERA COM 632307104 3,225,879 -163,720 -4.83 739,017 35.44 0.0248
2025-11-14 2025-09-30 13F NATERA COM 632307104 3,389,599 72,087 2.17 545,624 -2.65 0.0189
2025-08-14 2025-06-30 13F NATERA COM 632307104 3,317,512 -53,039 -1.57 560,460 17.59 0.0210
2025-05-15 2025-03-31 13F NATERA COM 632307104 3,370,551 379,580 12.69 476,630 0.67 0.0196
2025-02-14 2024-12-31 13F NATERA COM 632307104 2,990,971 -503,369 -14.41 473,471 6.73 0.0187
2024-11-14 2024-09-30 13F NATERA COM 632307104 3,494,340 -78,456 -2.20 443,606 14.66 0.0181
2024-08-14 2024-06-30 13F NATERA COM 632307104 3,572,796 849,803 31.21 386,898 55.35 0.0169
2024-05-15 2024-03-31 13F NATERA COM 632307104 2,722,993 -462,690 -14.52 249,045 24.80 0.0111
2024-02-14 2023-12-31 13F NATERA COM 632307104 3,185,683 207,907 6.98 199,551 51.44 0.0097
2023-11-14 2023-09-30 13F NATERA COM 632307104 2,977,776 -130,939 -4.21 131,767 -12.89 0.0073
2023-08-14 2023-06-30 13F NATERA COM 632307104 3,108,715 361,377 13.15 151,270 -0.83 0.0079
2023-05-15 2023-03-31 13F NATERA COM 632307104 2,747,338 -824,924 -23.09 152,532 6.30 0.0086
2023-05-15 2022-12-31 13F/A-99 NATERA COM 632307104 3,572,262 764,812 27.24 143,498 16.64 0.0084
2023-05-15 2022-12-31 13F NATERA COM 632307104 3,572,262 764,812 143,498 0.0084
2022-11-15 2022-09-30 13F NATERA COM 632307104 2,807,450 -601,922 -17.65 123,022 1.82 0.0078
2022-08-15 2022-06-30 13F NATERA COM 632307104 3,409,372 577,106 20.38 120,828 4.87 0.0072
2022-05-16 2022-03-31 13F NATERA COM 632307104 2,832,266 1,002,444 54.78 115,217 -32.58 0.0057
2022-02-14 2021-12-31 13F NATERA COM 632307104 1,829,822 204,621 12.59 170,887 -5.65 0.0081
2021-11-15 2021-09-30 13F NATERA COM 632307104 1,625,201 91,216 5.95 181,112 4.00 0.0096
2021-08-16 2021-06-30 13F NATERA COM 632307104 1,533,985 -375,258 -19.65 174,153 -10.17 0.0092
2021-07-09 2021-03-31 13F/A-1 NATERA COM 632307104 1,909,243 -207,826 -9.82 193,865 -7.99 0.0111
2021-05-17 2021-03-31 13F NATERA COM 632307104 1,909,243 -207,826 193,865 0.0111
2021-02-16 2020-12-31 13F NATERA COM 632307104 2,117,069 -80,893 -3.68 210,691 32.69 0.0129
2020-11-10 2020-09-30 13F NATERA COM 632307104 2,197,962 -509,318 -18.81 158,781 17.63 0.0108
2020-08-14 2020-06-30 13F NATERA COM 632307104 2,707,280 168,826 6.65 134,985 78.09 0.0098
2020-06-19 2020-03-31 13F/A-1 NATERA COM 632307104 2,538,454 47,857 1.92 75,798 -9.67 0.0066
2020-05-11 2020-03-31 13F NATERA COM 632307104 2,538,454 47,857 75,798 6,656.5906
2020-02-06 2019-12-31 13F NATERA COM 632307104 2,490,597 425,079 20.58 83,908 23.85 0.0057
2019-11-14 2019-09-30 13F NATERA COM 632307104 2,065,518 95,038 4.82 67,749 24.66 0.0050
2019-08-14 2019-06-30 13F NATERA COM 632307104 1,970,480 253,756 14.78 54,346 53.52 0.0041
2019-05-15 2019-03-31 13F NATERA COM 632307104 1,716,724 -477,192 -21.75 35,399 15.58 0.0028
2019-02-12 2018-12-31 13F NATERA COM 632307104 2,193,916 377,092 20.76 30,627 -29.59 0.0028
2018-11-09 2018-09-30 13F NATERA Common equity shares 632307104 1,816,824 1,245,143 217.80 43,496 304.13 0.0033
2018-08-14 2018-06-30 13F NATERA Common equity shares 632307104 571,681 41,506 7.83 10,763 119.12 0.0009
2018-05-15 2018-03-31 13F NATERA Common equity shares 632307104 530,175 8,424 1.61 4,912 4.76 0.0004
2018-02-14 2017-12-31 13F NATERA Common equity shares 632307104 521,751 52,432 11.17 4,689 -22.46 0.0004
2017-11-14 2017-09-30 13F NATERA Common equity shares 632307104 469,319 20,611 4.59 6,047 24.04 0.0005
2017-08-14 2017-06-30 13F NATERA Common equity shares 632307104 448,708 47,405 11.81 4,875 36.90 0.0004
2017-05-15 2017-03-31 13F NATERA Common equity shares 632307104 401,303 11,805 3.03 3,561 -21.93 0.0003
2017-02-09 2016-12-31 13F NATERA Common equity shares 632307104 389,498 11,067 2.92 4,561 8.49 0.0004
2017-01-13 2016-09-30 13F/A-1 NATERA Common equity shares 632307104 378,431 15,542 4.28 4,204 -3.95 0.0004
2016-11-14 2016-09-30 13F NATERA Common equity shares 632307104 378,431 4,204
2016-08-12 2016-06-30 13F NATERA Common equity shares 632307104 362,889 241,055 197.86 4,377 277.33 0.0005
2016-05-20 2016-03-31 13F/A-1 NATERA Common equity shares 632307104 121,834 11,078 10.00 1,160 -3.01 0.0001
2016-05-12 2016-03-31 13F NATERA Common equity shares 632307104 121,834 1,160
2016-02-16 2015-12-31 13F NATERA Common equity shares 632307104 110,756 20,368 22.53 1,196 22.04 0.0001
2015-11-16 2015-09-30 13F NATERA Common equity shares 632307104 90,388 90,388 980 0.0001
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.