Medical Properties Trust, Inc.
US ˙ NYSE ˙ US58463J3041

SecurityMPT / Medical Properties Trust, Inc.
InstitutionTwo Sigma Advisers, Lp
Latest Disclosed Ownership4,432,000 shares
Latest Disclosed Value $ 22,160,000
Two Sigma Advisers, Lp reports 58.56% increase in ownership of MPT / Medical Properties Trust, Inc.

On February 17, 2026 - Two Sigma Advisers, Lp filed a 13F-HR form disclosing ownership of 4,432,000 shares of Medical Properties Trust, Inc. (US:MPT) valued at $22,160,000 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 14, 2025 disclosing 2,795,100 shares of Medical Properties Trust, Inc.. This represents a change in shares of 58.56% during the quarter. The current value of the position is $22,071,360 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-02-17 2025-12-31 13F MEDICAL PPTYS TRUST COM 58463J304 4,432,000 1,636,900 58.56 22,160 56.38 0.0431
2025-11-14 2025-09-30 13F MEDICAL PPTYS TRUST COM 58463J304 2,795,100 2,552,800 1,053.57 14,171 1,257.38 0.0284
2025-08-14 2025-06-30 13F MEDICAL PPTYS TRUST COM 58463J304 242,300 -25,800 -9.62 1,044 -35.40 0.0021
2025-05-15 2025-03-31 13F MEDICAL PPTYS TRUST COM 58463J304 268,100 268,100 1,617 0.0036
2025-02-14 2024-12-31 13F MEDICAL PPTYS TRUST COM 58463J304 0 -13,200 -100.00 0 -100.00
2024-11-14 2024-09-30 13F MEDICAL PPTYS TRUST COM 58463J304 13,200 13,200 77 0.0002
2024-08-14 2024-06-30 13F MEDICAL PPTYS TRUST COM 58463J304 0 -89,600 -100.00 0 -100.00
2024-05-15 2024-03-31 13F MEDICAL PPTYS TRUST COM 58463J304 89,600 89,600 421 0.0010
2021-08-16 2021-06-30 13F MEDICAL PPTYS TRUST COM 58463J304 0 -93,831 -100.00 0 -100.00
2021-05-17 2021-03-31 13F MEDICAL PPTYS TRUST COM 58463J304 93,831 -1,062,600 -91.89 1,997 -92.08 0.0055
2021-02-16 2020-12-31 13F MEDICAL PPTYS TRUST COM 58463J304 1,156,431 -61,500 -5.05 25,199 17.36 0.0673
2020-11-16 2020-09-30 13F MEDICAL PPTYS TRUST COM 58463J304 1,217,931 1,071,700 732.88 21,472 681.08 0.0613
2020-09-15 2020-06-30 13F/A-1 MEDICAL PPTYS TRUST COM 58463J304 146,231 80,600 122.81 2,749 142.20 0.0081
2020-08-14 2020-06-30 13F MEDICAL PPTYS TRUST COM 58463J304 146,231 80,600 2,749 7,943.6970
2020-05-15 2020-03-31 13F MEDICAL PPTYS TRUST COM 58463J304 65,631 65,631 1,135 0.0043
2019-11-14 2019-09-30 13F MEDICAL PPTYS TRUST COM 58463J304 0 -300,831 -100.00 0 -100.00
2019-08-14 2019-06-30 13F MEDICAL PPTYS TRUST COM 58463J304 300,831 161,400 115.76 5,246 103.25 0.0131
2019-05-15 2019-03-31 13F MEDICAL PPTYS TRUST COM 58463J304 139,431 24,200 21.00 2,581 39.29 0.0065
2019-02-14 2018-12-31 13F MEDICAL PPTYS TRUST COM 58463J304 115,231 115,231 1,853 0.0051
2017-05-15 2017-03-31 13F MEDICAL PPTYS TRUST COM 58463J304 0 -387,994 -100.00 0 -100.00
2017-02-14 2016-12-31 13F MEDICAL PPTYS TRUST COM 58463J304 387,994 -183,031 -32.05 4,772 -43.42 0.0183
2016-11-14 2016-09-30 13F MEDICAL PPTYS TRUST COM 58463J304 571,025 559,331 4,783.06 8,434 4,638.20 0.0359
2016-08-15 2016-06-30 13F MEDICAL PPTYS TRUST COM 58463J304 11,694 11,694 0.00 178 0.0009
2016-05-16 2016-03-31 13F MEDICAL PPTYS TRUST COM 58463J304 0 0 0 0.0000
2015-05-15 2015-03-31 13F MEDICAL PPTYS TRUST COM 58463J304 0 -15,825 -100.00 0 -100.00
2016-02-09 2014-12-31 13F/A-1 MEDICAL PPTYS TRUST COM 58463J304 15,825 -32,300 -67.12 218 -62.86 0.0017
2015-02-17 2014-12-31 13F MEDICAL PPTYS TRUST COM 58463J304 15,825 218
2014-02-14 2013-12-31 13F Medical Properties Trust REIT 58463J304 48,125 48,125 587 0.0057
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.