Milestone Scientific Inc.
US ˙ NYSEAM ˙ US59935P2092

SecurityMLSS / Milestone Scientific Inc.
InstitutionVanguard Group Inc
Latest Disclosed Ownership2,349,317 shares
Latest Disclosed Value $ 641,364
Vanguard Group Inc reports 0.27% decrease in ownership of MLSS / Milestone Scientific Inc.

On January 29, 2026 - Vanguard Group Inc filed a 13F-HR form disclosing ownership of 2,349,317 shares of Milestone Scientific Inc. (US:MLSS) valued at $641,364 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 7, 2025 disclosing 2,355,695 shares of Milestone Scientific Inc.. This represents a change in shares of -0.27% during the quarter. The current value of the position is $1,019,604 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-01-29 2025-12-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,349,317 -6,378 -0.27 641 -40.04 0.0000
2025-11-07 2025-09-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,355,695 172,824 7.92 1,069 -23.09 0.0000
2025-08-11 2025-06-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,182,871 0 0.00 1,390 -31.73 0.0000
2025-05-09 2025-03-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,182,871 3,187 0.15 2,037 -2.68 0.0000
2025-02-11 2024-12-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,179,684 0 0.00 2,092 5.39 0.0000
2024-11-13 2024-09-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,179,684 34,556 1.61 1,986 35.49 0.0000
2024-08-13 2024-06-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,145,128 0 0.00 1,466 9.66 0.0000
2024-05-10 2024-03-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,145,128 373 0.02 1,336 -9.67 0.0000
2024-03-11 2023-12-31 13F/A-1 MILESTONE SCIENTIFIC COM NEW 59935P209 2,144,755 380 0.02 1,480 -25.00 0.0000
2024-02-14 2023-12-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,144,755 380 1,480 0.0000
2023-12-18 2023-09-30 13F/A-1 MILESTONE SCIENTIFIC COM NEW 59935P209 2,144,375 0 0.00 1,973 5.68 0.0000
2023-11-14 2023-09-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,144,375 0 1,973 0.0000
2023-08-14 2023-06-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,144,375 0 0.00 1,867 -3.27 0.0000
2023-07-14 2023-03-31 13F/A-1 MILESTONE SCIENTIFIC COM NEW 59935P209 2,144,375 0 0.00 1,930 87.46 0.0000
2023-05-15 2023-03-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,144,375 0 1,930 0.0000
2023-02-10 2022-12-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,144,375 983 0.05 1,029 -39.26 0.0000
2022-11-14 2022-09-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,143,392 0 0.00 1,694 -13.70 0.0000
2022-08-12 2022-06-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,143,392 0 0.00 1,963 -39.75 0.0001
2022-05-13 2022-03-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,143,392 -8,982 -0.42 3,258 -26.54 0.0001
2022-02-14 2021-12-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,152,374 -2,890 -0.13 4,435 10.02 0.0001
2021-11-12 2021-09-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,155,264 35,561 1.68 4,031 -22.38 0.0001
2021-08-13 2021-06-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,119,703 -406,858 -16.10 5,193 -42.43 0.0001
2021-05-14 2021-03-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,526,561 -19,259 -0.76 9,020 67.10 0.0002
2021-02-12 2020-12-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,545,820 -65,219 -2.50 5,398 48.75 0.0002
2020-11-16 2020-09-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 2,611,039 751,729 40.43 3,629 0.08 0.0001
2020-08-14 2020-06-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 1,859,310 990,303 113.96 3,626 233.89 0.0001
2020-05-15 2020-03-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 869,007 333,841 62.38 1,086 45.97 0.0000
2020-02-14 2019-12-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 535,166 284,931 113.87 744 257.69 0.0000
2019-11-14 2019-09-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 250,235 115,748 86.07 208 333.33 0.0000
2019-08-14 2019-06-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 134,487 35,886 36.40 48 45.45 0.0000
2019-05-15 2019-03-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 98,601 20,000 25.44 33 26.92 0.0000
2019-02-14 2018-12-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 78,601 470 0.60 26 -55.17 0.0000
2018-12-13 2018-09-30 13F/A-2 MILESTONE SCIENTIFIC COM NEW 59935P209 78,131 5,834 8.07 58 1.75 0.0000
2018-11-23 2018-09-30 13F/A-1 MILESTONE SCIENTIFIC COM NEW 59935P209 78,131 0 58 0.0000
2018-11-14 2018-09-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 78,131 5,834 58
2018-08-14 2018-06-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 72,297 2,060 2.93 57 11.76 0.0000
2018-05-15 2018-03-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 70,237 3,500 5.24 51 -35.44 0.0000
2018-02-14 2017-12-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 66,737 14,200 27.03 79 19.70 0.0000
2017-11-14 2017-09-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 52,537 11,737 28.77 66 8.20 0.0000
2017-08-24 2017-06-30 13F/A-1 MILESTONE SCIENTIFIC COM NEW 59935P209 40,800 1,400 3.55 61 15.09 0.0000
2017-08-11 2017-06-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 40,800 1,400 61
2017-05-12 2017-03-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 39,400 16,488 71.96 53 70.97 0.0000
2017-02-14 2016-12-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 22,912 4,200 22.45 31 -22.50 0.0000
2016-11-14 2016-09-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 18,712 5,167 38.15 40 5.26 0.0000
2016-08-10 2016-06-30 13F MILESTONE SCIENTIFIC COM NEW 59935P209 13,545 0 0.00 38 90.00 0.0000
2016-05-13 2016-03-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 13,545 0 0.00 20 -37.50 0.0000
2016-02-08 2015-12-31 13F MILESTONE SCIENTIFIC COM NEW 59935P209 13,545 13,545 32 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.