MeiraGTx Holdings plc
US ˙ NasdaqGS ˙ KYG596651029

SecurityMGTX / MeiraGTx Holdings plc
InstitutionD. E. Shaw & Co., Inc.
ManagerDE Shaw
Latest Disclosed Ownership425,281 shares
Latest Disclosed Value $ 3,682,933
D. E. Shaw & Co., Inc. reports 11.40% increase in ownership of MGTX / MeiraGTx Holdings plc

On May 15, 2026 - D. E. Shaw & Co., Inc. filed a 13F-HR form disclosing ownership of 425,281 shares of MeiraGTx Holdings plc (US:MGTX) valued at $3,682,933 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 381,763 shares of MeiraGTx Holdings plc. This represents a change in shares of 11.40% during the quarter. The current value of the position is $3,993,389 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F MEIRAGTX HLDGS COM G59665102 425,281 43,518 11.40 3,683 21.32 0.0022
2026-02-17 2025-12-31 13F MEIRAGTX HLDGS COM G59665102 381,763 208,561 120.41 3,035 112.98 0.0017
2025-11-14 2025-09-30 13F MEIRAGTX HLDGS COM G59665102 173,202 173,202 1,425 0.0008
2025-08-14 2025-06-30 13F MEIRAGTX HLDGS COM G59665102 0 -44,811 -100.00 0 -100.00
2025-05-15 2025-03-31 13F MEIRAGTX HLDGS COM G59665102 44,811 -78,832 -63.76 304 -59.71 0.0003
2025-02-14 2024-12-31 13F MEIRAGTX HLDGS COM G59665102 123,643 36,008 41.09 753 106.03 0.0006
2024-11-14 2024-09-30 13F MEIRAGTX HLDGS COM G59665102 87,635 18,527 26.81 365 25.86 0.0003
2024-08-14 2024-06-30 13F MEIRAGTX HLDGS COM G59665102 69,108 318 0.46 291 -30.46 0.0003
2024-05-15 2024-03-31 13F MEIRAGTX HLDGS COM G59665102 68,790 32,206 88.03 418 62.89 0.0004
2024-02-14 2023-12-31 13F MEIRAGTX HLDGS COM G59665102 36,584 36,584 257 0.0002
2020-11-16 2020-09-30 13F MEIRAGTX HLDGS COM G59665102 0 -10,454 -100.00 0 -100.00
2020-08-14 2020-06-30 13F MEIRAGTX HLDGS COM G59665102 10,454 0 0.00 131 -7.09 0.0002
2020-05-15 2020-03-31 13F MEIRAGTX HOLDINGS COM G59665102 10,454 -2,000 -16.06 141 -43.37 0.0002
2020-02-14 2019-12-31 13F MEIRAGTX HOLDINGS COM G59665102 12,454 12,454 249 0.0003
2019-11-14 2019-09-30 13F MEIRAGTX HOLDINGS COM G59665102 0 -23,947 -100.00 0 -100.00
2019-08-14 2019-06-30 13F MEIRAGTX HOLDINGS COM G59665102 23,947 9,341 63.95 644 155.56 0.0008
2019-05-15 2019-03-31 13F MEIRAGTX HOLDINGS COM G59665102 14,606 14,606 252 0.0003
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.