Madrigal Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US5588681057

SecurityMDGL / Madrigal Pharmaceuticals, Inc.
InstitutionAvoro Capital Advisors LLC
Latest Disclosed Ownership2,288,888 shares
Ownership 9.90%
Avoro Capital Advisors LLC ownership in MDGL / Madrigal Pharmaceuticals, Inc.

2024-02-14 - Avoro Capital Advisors LLC has filed an SC 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 2,288,888 shares of Madrigal Pharmaceuticals, Inc. (US:MDGL). This represents 9.9 percent ownership of the company. In their previous filing dated 2023-02-14 , Avoro Capital Advisors LLC had reported owning 1,660,000 shares, indicating an increase of 37.88 percent.

Institutional Ownership: 13D/G Filings

This table shows a history of the 13D/G filings made by the investor and/or investor group. Note that the share values in this table are not directly comparable to any numbers shown in the 13F table (if any).

File
Date
Effective
Date
Form Prev
Shares
Latest
Shares
ΔShares
(Percent)
Ownership
(Percent)
ΔOwnership
(Percent)
2024-02-14 2024-02-14 13G/A 1,660,000 2,288,888 37.88 9.90 2.06
2023-02-14 2023-02-14 13G/A 1,425,000 1,660,000 16.49 9.70 16.87
2022-02-11 2022-02-11 13G/A 1,225,000 1,425,000 16.33 8.30 5.06
2021-02-12 2021-02-12 13G 1,225,000 7.90

Important Note: One of the primary uses of the 13D/G filings is to evaluate the ability of a firm to control a company (ie, the "beneficial ownership"). To that end, firms are required to report not just direct holdings in companies, but indirect holdings that they control. For investment firms, these indirect holdings can include shares in funds they manage, advisory accounts, and in the case of activist campaigns, pledged votes. Therefore, share counts listed in 13D/G filings can differ significantly than share counts listed in 13F filings.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,818,181 10,681 0.59 951,763 -9.58 9.3581
2026-03-13 2025-12-31 13F/A-1 MADRIGAL PHARMACEUTICALS Common 558868105 1,807,500 -25,500 -1.39 1,052,580 25.20 10.3454
2026-02-17 2025-12-31 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,807,500 -25,500 1,052,580 10.3454
2025-11-14 2025-09-30 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,833,000 -42,000 -2.24 840,724 48.16 10.8670
2025-08-14 2025-06-30 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,875,000 -147,222 -7.28 567,450 -15.28 9.9373
2025-05-15 2025-03-31 13F MADRIGAL PHARMACEUTICALS Common 558868105 2,022,222 -6,778 -0.33 669,821 6.98 10.4552
2025-02-14 2024-12-31 13F MADRIGAL PHARMACEUTICALS Common 558868105 2,029,000 0 0.00 626,089 45.40 8.8556
2024-11-14 2024-09-30 13F MADRIGAL PHARMACEUTICALS Common 558868105 2,029,000 -26,555 -1.29 430,594 -25.23 6.2786
2024-08-14 2024-06-30 13F MADRIGAL PHARMACEUTICALS Common 558868105 2,055,555 111,111 5.71 575,884 10.91 7.6699
2024-05-15 2024-03-31 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,944,444 55,556 2.94 519,244 18.81 6.0564
2024-02-14 2023-12-31 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,888,888 333,888 21.47 437,051 92.46 6.0368
2023-11-14 2023-09-30 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,555,000 39,849 2.63 227,092 -35.12 3.5421
2023-08-14 2023-06-30 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,515,151 -151,515 -9.09 350,000 -13.32 4.7482
2023-05-15 2023-03-31 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,666,666 6,666 0.40 403,767 -16.20 5.9860
2023-02-14 2022-12-31 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,660,000 125,000 8.14 481,815 382.97 7.2004
2022-11-14 2022-09-30 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,535,000 0 0.00 99,760 -9.21 1.8430
2022-08-15 2022-06-30 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,535,000 110,000 7.72 109,875 -21.42 2.1712
2022-05-16 2022-03-31 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,425,000 0 0.00 139,821 15.79 2.5526
2022-02-14 2021-12-31 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,425,000 0 0.00 120,755 6.20 2.0551
2021-11-15 2021-09-30 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,425,000 0 0.00 113,701 -18.09 1.7861
2021-08-16 2021-06-30 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,425,000 0 0.00 138,809 -16.72 2.4147
2021-05-17 2021-03-31 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,425,000 200,000 16.33 166,682 22.40 2.8787
2021-02-16 2020-12-31 13F MADRIGAL PHARMACEUTICALS Common 558868105 1,225,000 335,000 37.64 136,183 28.88 2.3453
2020-11-16 2020-09-30 13F MADRIGAL PHARMACEUTICALS Common 558868105 890,000 540,000 154.29 105,670 166.59 1.5013
2020-08-14 2020-06-30 13F MADRIGAL PHARMACEUTICALS Common 558868105 350,000 1,000 0.29 39,638 70.13 0.7837
2020-05-15 2020-03-31 13F MADRIGAL PHARMACEUTICALS Common 558868105 349,000 0 0.00 23,299 -26.73 0.7864
2020-02-14 2019-12-31 13F MADRIGAL PHARMACEUTICALS Common 558868105 349,000 -11,000 -3.06 31,797 2.44 0.9337
2019-11-14 2019-09-30 13F MADRIGAL PHARMACEUTICALS Common 558868105 360,000 0 0.00 31,039 -17.74 1.2948
2019-08-14 2019-06-30 13F MADRIGAL PHARMACEUTICALS Common 558868105 360,000 50,000 16.13 37,732 -2.83 1.3043
2019-05-15 2019-03-31 13F MADRIGAL PHARMACEUTICALS Common 558868105 310,000 85,000 37.78 38,831 53.11 1.6791
2019-02-14 2018-12-31 13F MADRIGAL PHARMACEUTICALS Common 558868105 225,000 -238,000 -51.40 25,362 -74.42 1.5161
2018-11-14 2018-09-30 13F MADRIGAL PHARMACEUTICALS Common 558868105 463,000 -26,536 -5.42 99,142 -27.59 4.5527
2018-08-14 2018-06-30 13F MADRIGAL PHARMACEUTICALS Common 558868105 489,536 489,536 136,918 5.2708
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.