Madrigal Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US5588681057

SecurityMDGL / Madrigal Pharmaceuticals, Inc.
InstitutionDimensional Fund Advisors Lp
Latest Disclosed Ownership8,520 shares
Latest Disclosed Value $ 4,459,964
Dimensional Fund Advisors Lp reports 55.90% decrease in ownership of MDGL / Madrigal Pharmaceuticals, Inc.

On May 7, 2026 - Dimensional Fund Advisors Lp filed a 13F-HR form disclosing ownership of 8,520 shares of Madrigal Pharmaceuticals, Inc. (US:MDGL) valued at $4,459,964 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 19,321 shares of Madrigal Pharmaceuticals, Inc.. This represents a change in shares of -55.90% during the quarter. The current value of the position is $4,159,038 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-07 2026-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 8,520 -10,801 -55.90 4,460 -60.37 0.0002
2026-02-12 2025-12-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 19,321 13,522 233.18 11,251 323.13 0.0024
2025-11-12 2025-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 5,799 1,929 49.84 2,660 127.07 0.0006
2025-08-12 2025-06-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 3,870 26 0.68 1,171 -8.01 0.0003
2025-05-13 2025-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 3,844 3,844 1,273 0.0003
2023-11-09 2023-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 0 -16,345 -100.00 0 -100.00
2023-08-09 2023-06-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 16,345 44 0.27 3,776 -4.41 0.0012
2023-05-12 2023-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 16,301 3,222 24.63 3,949 131,533.33 0.0013
2023-02-09 2022-12-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 13,079 -32,916 -71.56 4 -99.90 0.0011
2022-11-10 2022-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 45,995 -123,299 -72.83 2,989 -75.33 0.0011
2022-08-12 2022-06-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 169,294 -46,903 -21.69 12,117 -42.88 0.0043
2022-05-13 2022-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 216,197 13,885 6.86 21,214 23.74 0.0065
2022-02-09 2021-12-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 202,312 27,900 16.00 17,144 23.19 0.0052
2021-11-12 2021-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 174,412 5,240 3.10 13,917 -15.55 0.0045
2021-08-12 2021-06-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 169,172 -3,339 -1.94 16,479 -18.33 0.0052
2021-05-14 2021-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 172,511 -16,319 -8.64 20,178 -3.88 0.0067
2021-03-08 2020-12-31 13F/A-2 MADRIGAL PHARMACEUTICALS COM 558868105 188,830 -10,934 -5.47 20,992 -11.49 0.0076
2021-02-11 2020-12-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 188,830 -10,934 20,992 7,581.1946
2020-11-12 2020-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 199,764 744 0.37 23,718 5.27 0.0101
2020-08-13 2020-06-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 199,020 1,342 0.68 22,531 70.70 0.0099
2020-05-14 2020-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 197,678 12,134 6.54 13,199 -21.92 0.0069
2020-02-14 2019-12-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 185,544 70,222 60.89 16,904 70.01 0.0062
2019-11-12 2019-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 115,322 26,146 29.32 9,943 6.39 0.0039
2019-08-13 2019-06-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 89,176 71,906 416.36 9,346 331.89 0.0036
2019-08-12 2019-03-31 13F/A-2 MADRIGAL PHARMACEUTICALS COM 558868105 17,270 9,608 125.40 2,164 151.04 0.0009
2019-05-10 2019-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 17,270 9,608 2,164
2019-02-26 2018-12-31 13F/A-1 MADRIGAL PHARMACEUTICALS COM 558868105 7,662 -3,643 -32.22 862 -64.38 0.0004
2019-02-13 2018-12-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 7,662 -3,643 862
2018-11-13 2018-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 11,305 6,512 135.86 2,420 80.60 0.0009
2018-08-10 2018-06-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 4,793 4,793 1,340 0.0005
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.