Lakefront Biotherapeutics NV - Depositary Receipt (Common Stock)
US ˙ NasdaqGS ˙ US36315X1019

SecurityLKFT / Lakefront Biotherapeutics NV - Depositary Receipt (Common Stock)
InstitutionEcoR1 Capital, LLC
Latest Disclosed Ownership8,714,522 shares
Ownership 13.22%
EcoR1 Capital, LLC ownership in LKFT / Lakefront Biotherapeutics NV - Depositary Receipt (Common Stock)

2025-07-28 - EcoR1 Capital, LLC has filed an SCHEDULE 13D/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 8,714,522 shares of Lakefront Biotherapeutics NV - Depositary Receipt (Common Stock) (US:LKFT). This represents 13.22 percent ownership of the company. In their previous filing dated 2025-05-19 , EcoR1 Capital, LLC had reported owning 7,803,202 shares, indicating an increase of 11.68 percent.

Institutional Ownership: 13D/G Filings

This table shows a history of the 13D/G filings made by the investor and/or investor group. Note that the share values in this table are not directly comparable to any numbers shown in the 13F table (if any).

File
Date
Effective
Date
Form Prev
Shares
Latest
Shares
ΔShares
(Percent)
Ownership
(Percent)
ΔOwnership
(Percent)
2025-07-28 2025-07-28 13D/A 7,803,202 8,714,522 11.68 13.22 11.66
2025-05-19 2025-05-19 13D/A 7,094,049 7,803,202 10.00 11.84 9.94
2024-10-08 2024-10-08 13D/A 6,505,890 7,094,049 9.04 10.77 8.79
2024-08-23 2024-08-23 13D 6,505,890 6,505,890 0.00 9.90 0.00
2024-02-14 2024-02-14 13G/A 6,505,890 6,505,890 0.00 9.90 0.00
2023-06-07 2023-06-07 13G 4,442,352 6,505,890 46.45 9.90 47.76
2023-02-14 2023-02-14 13G/A 3,407,246 4,442,352 30.38 6.70 28.85
2022-02-03 2022-02-03 13G 3,407,246 5.20

Important Note: One of the primary uses of the 13D/G filings is to evaluate the ability of a firm to control a company (ie, the "beneficial ownership"). To that end, firms are required to report not just direct holdings in companies, but indirect holdings that they control. For investment firms, these indirect holdings can include shares in funds they manage, advisory accounts, and in the case of activist campaigns, pledged votes. Therefore, share counts listed in 13D/G filings can differ significantly than share counts listed in 13F filings.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F GALAPAGOS SPON ADR 36315X101 1,667,119 0 0.00 50,014 -8.26 2.1225
2026-02-17 2025-12-31 13F GALAPAGOS SPON ADR 36315X101 1,667,119 0 0.00 54,515 -5.60 2.4734
2025-11-14 2025-09-30 13F GALAPAGOS SPON ADR 36315X101 1,667,119 630,174 60.77 57,749 98.97 2.7712
2025-08-14 2025-06-30 13F GALAPAGOS SPON ADR 36315X101 1,036,945 881,939 568.97 29,024 645.54 1.7181
2025-05-15 2025-03-31 13F GALAPAGOS SPON ADR 36315X101 155,006 0 0.00 3,894 -8.66 0.2309
2025-02-14 2024-12-31 13F GALAPAGOS SPON ADR 36315X101 155,006 0 0.00 4,263 -4.48 0.1612
2024-11-14 2024-09-30 13F GALAPAGOS SPON ADR 36315X101 155,006 -5,601,262 -97.31 4,463 -96.87 0.1527
2024-08-14 2024-06-30 13F GALAPAGOS SPON ADR 36315X101 5,756,268 0 0.00 142,640 -23.04 4.3636
2024-05-15 2024-03-31 13F GALAPAGOS SPON ADR 36315X101 5,756,268 0 0.00 185,352 -20.79 4.6880
2024-02-14 2023-12-31 13F GALAPAGOS SPON ADR 36315X101 5,756,268 0 0.00 233,992 17.66 6.0753
2023-11-14 2023-09-30 13F GALAPAGOS SPON ADR 36315X101 5,756,268 0 0.00 198,879 -15.03 6.7082
2023-08-14 2023-06-30 13F GALAPAGOS SPON ADR 36315X101 5,756,268 1,511,623 35.61 234,050 42.70 5.7344
2023-05-15 2023-03-31 13F GALAPAGOS SPON ADR 36315X101 4,244,645 513,915 13.78 164,013 -0.94 5.2815
2023-02-14 2022-12-31 13F GALAPAGOS SPON ADR 36315X101 3,730,730 533,230 16.68 165,570 21.44 5.0393
2022-11-14 2022-09-30 13F GALAPAGOS SPON ADR 36315X101 3,197,500 0 0.00 136,341 -23.58 4.0241
2022-08-15 2022-06-30 13F GALAPAGOS SPON ADR 36315X101 3,197,500 1,876 0.06 178,420 -9.98 6.1587
2022-05-16 2022-03-31 13F GALAPAGOS SPON ADR 36315X101 3,195,624 971,221 43.66 198,193 61.62 6.1997
2022-02-14 2021-12-31 13F GALAPAGOS SPON ADR 36315X101 2,224,403 665,654 42.70 122,631 49.54 3.9079
2021-11-22 2021-09-30 13F/A-1 GALAPAGOS SPON ADR 36315X101 1,558,749 1,558,749 82,006 2.8529
2021-11-15 2021-09-30 13F GALAPAGOS SPON ADR 36315X101 1,558,749 1,558,749 82,006 2.8529
2021-05-17 2021-03-31 13F GALAPAGOS SPON ADR 36315X101 0 -46,666 -100.00 0 -100.00
2021-02-16 2020-12-31 13F GALAPAGOS SPON ADR 36315X101 46,666 46,666 4,619 0.2483
2018-05-15 2018-03-31 13F GALAPAGOS NV SPONSORED ADR 36315X101 0 -110,384 -100.00 0 -100.00
2018-02-14 2017-12-31 13F GALAPAGOS NV SPONSORED ADR 36315X101 110,384 -130,392 -54.15 10,350 -57.75 1.1654
2017-11-14 2017-09-30 13F GALAPAGOS NV SPON ADR SPONSORED ADR 36315X101 240,776 -337,729 -58.38 24,499 -44.66 3.2652
2017-08-14 2017-06-30 13F GALAPAGOS NV SPON ADR SPONSORED ADR 36315X101 578,505 27,464 4.98 44,267 -6.79 7.8595
2017-05-19 2017-03-31 13F/A-1 GALAPAGOS SPONSORED ADR 36315X101 551,041 -10,300 -1.83 47,494 31.81 12.0066
2017-05-15 2017-03-31 13F GALAPAGOS SPONSORED ADR 36315X101 551,041 47,494
2017-02-15 2016-12-31 13F/A-1 GALAPAGOS SPONSORED ADR 36315X101 561,341 60,765 12.14 36,032 11.32 12.0337
2017-02-14 2016-12-31 13F GALAPAGOS SPONSORED ADR 36315X101 561,341 36,032
2016-11-14 2016-09-30 13F GALAPAGOS SPONSORED ADR 36315X101 500,576 61,191 13.93 32,367 32.80 9.9318
2016-08-15 2016-06-30 13F GALAPAGOS SPONSORED ADR 36315X101 439,385 192,694 78.11 24,373 136.24 9.6100
2016-05-16 2016-03-31 13F GALAPAGOS SPONSORED ADR 36315X101 246,691 79,330 47.40 10,317 -1.97 3.6049
2016-02-16 2015-12-31 13F GALAPAGOS SPONSORED ADR 36315X101 167,361 167,361 10,524 3.3053
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.