Krystal Biotech, Inc.
US ˙ NasdaqGS ˙ US5011471027

SecurityKRYS / Krystal Biotech, Inc.
InstitutionAvoro Capital Advisors LLC
Latest Disclosed Ownership2,565,555 shares
Ownership 9.10%
Avoro Capital Advisors LLC ownership in KRYS / Krystal Biotech, Inc.

2024-02-14 - Avoro Capital Advisors LLC has filed an SC 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 2,565,555 shares of Krystal Biotech, Inc. (US:KRYS). This represents 9.1 percent ownership of the company. In their previous filing dated 2023-02-14 , Avoro Capital Advisors LLC had reported owning 1,410,000 shares, indicating an increase of 81.95 percent.

Institutional Ownership: 13D/G Filings

This table shows a history of the 13D/G filings made by the investor and/or investor group. Note that the share values in this table are not directly comparable to any numbers shown in the 13F table (if any).

File
Date
Effective
Date
Form Prev
Shares
Latest
Shares
ΔShares
(Percent)
Ownership
(Percent)
ΔOwnership
(Percent)
2024-02-14 2024-02-14 13G/A 1,410,000 2,565,555 81.95 9.10 65.45
2023-02-14 2023-02-14 13G 1,410,000 5.50

Important Note: One of the primary uses of the 13D/G filings is to evaluate the ability of a firm to control a company (ie, the "beneficial ownership"). To that end, firms are required to report not just direct holdings in companies, but indirect holdings that they control. For investment firms, these indirect holdings can include shares in funds they manage, advisory accounts, and in the case of activist campaigns, pledged votes. Therefore, share counts listed in 13D/G filings can differ significantly than share counts listed in 13F filings.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F KRYSTAL BIOTECH Common 501147102 2,888,888 0 0.00 746,258 4.78 7.3416
2026-03-13 2025-12-31 13F/A-1 KRYSTAL BIOTECH Common 501147102 2,888,888 111,111 4.00 712,226 45.25 7.0002
2026-02-17 2025-12-31 13F KRYSTAL BIOTECH Common 501147102 2,888,888 111,111 712,226 7.0002
2025-11-14 2025-09-30 13F KRYSTAL BIOTECH Common 501147102 2,777,777 117,777 4.43 490,361 34.11 6.3383
2025-08-14 2025-06-30 13F KRYSTAL BIOTECH Common 501147102 2,660,000 -71,000 -2.60 365,644 -25.74 6.4033
2025-05-15 2025-03-31 13F KRYSTAL BIOTECH Common 501147102 2,731,000 102,178 3.89 492,399 19.56 7.6859
2025-02-14 2024-12-31 13F KRYSTAL BIOTECH Common 501147102 2,628,822 6,600 0.25 411,831 -13.72 5.8251
2024-11-14 2024-09-30 13F KRYSTAL BIOTECH Common 501147102 2,622,222 189,222 7.78 477,323 6.83 6.9599
2024-08-14 2024-06-30 13F KRYSTAL BIOTECH Common 501147102 2,433,000 -122,555 -4.80 446,796 -1.74 5.9506
2024-05-15 2024-03-31 13F KRYSTAL BIOTECH Common 501147102 2,555,555 -10,000 -0.39 454,710 42.86 5.3037
2024-02-14 2023-12-31 13F KRYSTAL BIOTECH Common 501147102 2,565,555 0 0.00 318,283 6.95 4.3963
2023-11-14 2023-09-30 13F KRYSTAL BIOTECH Common 501147102 2,565,555 4,744 0.19 297,604 -1.01 4.6419
2023-08-14 2023-06-30 13F KRYSTAL BIOTECH Common 501147102 2,560,811 810,811 46.33 300,639 114.58 4.0786
2023-05-15 2023-03-31 13F KRYSTAL BIOTECH Common 501147102 1,750,000 340,000 24.11 140,105 25.43 2.0771
2023-02-14 2022-12-31 13F KRYSTAL BIOTECH Common 501147102 1,410,000 135,000 10.59 111,700 25.69 1.6693
2022-11-14 2022-09-30 13F KRYSTAL BIOTECH Common 501147102 1,275,000 200,000 18.60 88,868 25.90 1.6418
2022-08-15 2022-06-30 13F KRYSTAL BIOTECH Common 501147102 1,075,000 70,000 6.97 70,585 5.55 1.3948
2022-05-16 2022-03-31 13F KRYSTAL BIOTECH Common 501147102 1,005,000 530,000 111.58 66,873 101.27 1.2209
2022-02-14 2021-12-31 13F KRYSTAL BIOTECH Common 501147102 475,000 475,000 33,226 0.5655
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.