Ironwood Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US46333X1081

SecurityIRWD / Ironwood Pharmaceuticals, Inc.
InstitutionSei Investments Co
Latest Disclosed Ownership673,862 shares
Latest Disclosed Value $ 2,270,914
Sei Investments Co reports 1.43% decrease in ownership of IRWD / Ironwood Pharmaceuticals, Inc.

On February 13, 2026 - Sei Investments Co filed a 13F-HR form disclosing ownership of 673,862 shares of Ironwood Pharmaceuticals, Inc. (US:IRWD) valued at $2,270,915 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 13, 2025 disclosing 683,604 shares of Ironwood Pharmaceuticals, Inc.. This represents a change in shares of -1.43% during the quarter. The current value of the position is $2,230,483 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-02-13 2025-12-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 673,862 -9,742 -1.43 2,271 153.63 0.0022
2025-11-13 2025-09-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 683,604 0 0.00 896 82.65 0.0010
2025-08-14 2025-06-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 683,604 496,857 266.06 490 78.83 0.0006
2025-05-14 2025-03-31 13F/A-1 IRONWOOD PHARMACEUTICALS COM CL A 46333X108 186,747 44,832 31.59 275 -56.37 0.0004
2025-05-13 2025-03-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 141,879 -36 628 0.0007
2025-02-11 2024-12-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 141,915 -268,765 -65.44 629 -62.86 0.0008
2024-11-12 2024-09-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 410,680 410,680 1,692 0.0022
2024-05-07 2024-03-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 0 -190,143 -100.00 0 -100.00
2024-02-14 2023-12-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 190,143 144 0.08 2,175 18.92 0.0035
2023-11-14 2023-09-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 189,999 22,143 13.19 1,830 2.41 0.0033
2023-08-11 2023-06-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 167,856 -11,462 -6.39 1,786 -5.30 0.0031
2023-05-12 2023-03-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 179,318 9,082 5.33 1,886 -10.57 0.0035
2023-02-10 2022-12-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 170,236 17,918 11.76 2,109 33.65 0.0047
2022-11-14 2022-09-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 152,318 122,992 419.40 1,578 310.94 0.0035
2022-08-15 2022-06-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 29,326 323 1.11 384 -4.95 0.0008
2022-05-13 2022-03-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 29,003 529 1.86 404 7.73 0.0008
2022-02-14 2021-12-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 28,474 -102,533 -78.27 375 -78.47 0.0007
2021-11-12 2021-09-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 131,007 98,150 298.72 1,742 295.91 0.0037
2021-08-06 2021-06-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 32,857 32,857 440 0.0010
2021-05-12 2021-03-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 0 -230,146 -100.00 0 -100.00
2021-02-08 2020-12-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 230,146 9,306 4.21 2,593 32.84 0.0067
2020-12-04 2020-09-30 13F/A-1 IRONWOOD PHARMACEUTICALS COM CL A 46333X108 220,840 112,015 102.93 1,952 76.01 0.0057
2020-11-06 2020-09-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 220,921 112,096 1,953 4,702.3898
2020-08-17 2020-06-30 13F/A-1 IRONWOOD PHARMACEUTICALS COM CL A 46333X108 108,825 24,036 28.35 1,109 29.71 0.0034
2020-08-11 2020-06-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 90,816 6,027 1,112 3,016.3592
2020-05-14 2020-03-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 84,789 -2,570 -2.94 855 -26.48 0.0031
2020-02-06 2019-12-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 87,359 24,728 39.48 1,163 116.17 0.0035
2019-11-12 2019-09-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 62,631 857 1.39 538 -20.41 0.0014
2019-08-14 2019-06-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 61,774 61,774 -1.37 676 25.65 0.0022
2018-11-08 2018-09-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 0 -3,157 -100.00 0 -100.00
2018-08-03 2018-06-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 3,157 47 1.51 60 25.00 0.0002
2018-05-11 2018-03-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 3,110 -241,921 -98.73 48 -98.69 0.0002
2018-02-08 2017-12-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 245,031 -7,307 -2.90 3,673 -7.71 0.0128
2017-11-06 2017-09-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 252,338 28,513 12.74 3,980 -5.82 0.0141
2017-07-31 2017-06-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 223,825 22,599 11.23 4,226 23.10 0.0168
2017-05-05 2017-03-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 201,226 32,618 19.35 3,433 33.17 0.0150
2017-02-02 2016-12-31 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 168,608 168,547 276,306.56 2,578 257,700.00 0.0125
2016-11-04 2016-09-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 61 0 0.00 1 0.00 0.0000
2016-08-11 2016-06-30 13F IRONWOOD PHARMACEUTICALS COM CL A 46333X108 61 0 0.00 1 0.00 0.0000
2016-05-10 2016-03-31 13F/A-1 IRONWOOD PHARMACEUTICALS COM CL A 46333X108 61 61 0.00 1 0.00 0.0000
2016-02-03 2015-12-31 13F DIREXION SHS ETF TR COM CL A 46333X108 0 -52,761 -100.00 0 -100.00
2015-11-02 2015-09-30 13F/A-1 IRONWOOD PHARMACEUTICALS INC COM COM CL A 46333X108 52,761 52,761 550 0.0050
2015-10-30 2015-09-30 13F DIREXION SHS ETF TR COM CL A 46333X108 52,761 550
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.