Humacyte, Inc.
US ˙ NasdaqGS ˙ US44486Q1031

SecurityHUMA / Humacyte, Inc.
InstitutionCitadel Advisors Llc
ManagerKen Griffin
Latest Disclosed Ownership0 shares
Latest Disclosed Value $ 0
Citadel Advisors Llc ownership in HUMA / Humacyte, Inc.

On May 15, 2026 - Citadel Advisors Llc filed a 13F-HR form disclosing ownership of 0 shares of Humacyte, Inc. (US:HUMA) valued at $0 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 1,566,431 shares of Humacyte, Inc.. This represents a change in shares of -100.00% during the quarter. The current value of the position is $0 USD.

Citadel Advisors Llc has a history of taking positions in derivatives of the underlying security (HUMA) in the form of stock options. The firm currently holds call options representing 163,900 of underlying shares valued at $99,438 USD and put options representing 232,100 of underlying shares valued at $140,815 USD .

Note: prior versions of this page mistakenly stated that the share values represented the number of options, not the number of underlying shares. For more information on the data backing these reports, please see the SEC document Frequently Asked Questions About Form 13F.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Institutional Put/Call Ratios
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In addition to reporting standard equity and debt issues, institutions with more than 100MM assets under management must also disclose their put and call option holdings. Since put options generally indicate negative sentiment, and call options indicate positive sentiment, we can get a sense of the overall institutional sentiment by plotting the ratio of puts to calls. The chart to the right plots the historical put/call ratio for this instrument.

Using Put/Call Ratio as an indicator of investor sentiment overcomes one of the key deficiencies of using total institutional ownership, which is that a significant amount of assets under management are invested passively to track indices. Passively-managed funds do not typically buy options, so the put/call ratio indicator more closely tracks the sentiment of actively-managed funds.

HUMA / Humacyte, Inc. Historical Put/Call Ratio
Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F HUMACYTE COM 44486Q103 0 -1,566,431 -100.00 0 -100.00
2026-02-17 2025-12-31 13F HUMACYTE COM 44486Q103 1,566,431 673,479 75.42 1,505 -3.16 0.0002
2025-11-14 2025-09-30 13F HUMACYTE COM 44486Q103 892,952 268,194 42.93 1,554 19.00 0.0002
2025-08-14 2025-06-30 13F HUMACYTE COM 44486Q103 624,758 -2,287,143 -78.54 1,306 -73.71 0.0002
2025-05-15 2025-03-31 13F HUMACYTE COM 44486Q103 2,911,901 2,740,439 1,598.28 4,965 473.87 0.0009
2025-02-14 2024-12-31 13F HUMACYTE COM 44486Q103 171,462 18,318 11.96 866 3.84 0.0001
2024-11-14 2024-09-30 13F HUMACYTE COM 44486Q103 153,144 109,242 248.83 833 296.67 0.0002
2024-08-14 2024-06-30 13F HUMACYTE COM 44486Q103 43,902 -210,349 -82.73 211 -73.42 0.0000
2024-05-15 2024-03-31 13F HUMACYTE COM 44486Q103 254,251 69,121 37.34 791 50.48 0.0002
2024-02-14 2023-12-31 13F HUMACYTE COM 44486Q103 185,130 -93,457 -33.55 526 -35.66 0.0001
2023-11-14 2023-09-30 13F HUMACYTE COM 44486Q103 278,587 239,498 612.70 816 635.14 0.0002
2023-08-14 2023-06-30 13F HUMACYTE COM 44486Q103 39,089 39,089 112 0.0000
2023-05-15 2023-03-31 13F HUMACYTE COM 44486Q103 0 -510 -100.00 0 -100.00
2023-02-14 2022-12-31 13F HUMACYTE COM 44486Q103 510 -168,468 -99.70 1 -99.82 0.0000
2022-11-14 2022-09-30 13F HUMACYTE COM 44486Q103 168,978 -30,605 -15.33 551 -13.91 0.0001
2022-08-15 2022-06-30 13F HUMACYTE COM 44486Q103 199,583 147,415 282.58 640 73.91 0.0002
2022-05-16 2022-03-31 13F HUMACYTE COM 44486Q103 52,168 32,275 162.24 368 155.56 0.0001
2022-02-14 2021-12-31 13F HUMACYTE COM 44486Q103 19,893 19,893 144 0.0000
Disclosed Call Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share
Price
Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2026-05-15 2026-03-31 13F HUMACYTE COM Call 163,900 -34.62 99 -58.75 n/a n/a n/a
2026-02-17 2025-12-31 13F HUMACYTE COM Call 250,700 41.72 241 -21.82 n/a n/a n/a
2025-11-14 2025-09-30 13F HUMACYTE COM Call 176,900 -72.64 308 -77.28 n/a n/a n/a
2025-08-14 2025-06-30 13F HUMACYTE COM Call 646,500 3.32 1,351 26.74 n/a n/a n/a
2025-05-15 2025-03-31 13F HUMACYTE COM Call 625,700 396.98 1,067 67.87 n/a n/a n/a
2025-02-14 2024-12-31 13F HUMACYTE COM Call 125,900 142.12 636 125.18 n/a n/a n/a
2024-11-14 2024-09-30 13F HUMACYTE COM Call 52,000 319.35 283 377.97 n/a n/a n/a
2024-08-14 2024-06-30 13F HUMACYTE COM Call 12,400 -20.51 60 22.92 n/a n/a n/a
2024-05-15 2024-03-31 13F HUMACYTE COM Call 15,600 940.00 49 1,100.00 n/a n/a n/a
2024-02-14 2023-12-31 13F HUMACYTE COM Call 1,500 0.00 4 0.00 n/a n/a n/a
2023-11-14 2023-09-30 13F HUMACYTE COM Call 1,500 87.50 4 100.00 n/a n/a n/a
2023-08-14 2023-06-30 13F HUMACYTE COM Call 800 2 n/a n/a n/a
2023-05-15 2023-03-31 13F HUMACYTE COM Call 0 -100.00 0 -100.00 n/a n/a n/a
2023-02-14 2022-12-31 13F HUMACYTE COM Call 12,700 -45.96 27 -66.23 n/a n/a n/a
2022-11-14 2022-09-30 13F HUMACYTE COM Call 23,500 56.67 77 60.42 n/a n/a n/a
2022-08-15 2022-06-30 13F HUMACYTE COM Call 15,000 -51.46 48 -77.98 n/a n/a n/a
2022-05-16 2022-03-31 13F HUMACYTE COM Call 30,900 15.73 218 12.37 n/a n/a n/a
2022-02-14 2021-12-31 13F HUMACYTE COM Call 26,700 17.11 194 -26.79 n/a n/a n/a
2021-11-15 2021-09-30 13F HUMACYTE Cmn Call 22,800 265 n/a n/a n/a
Disclosed Put Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share Price Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2026-05-15 2026-03-31 13F HUMACYTE COM Put 232,100 73.34 141 9.38 n/a n/a n/a
2026-02-17 2025-12-31 13F HUMACYTE COM Put 133,900 82.67 129 0.79 n/a n/a n/a
2025-11-14 2025-09-30 13F HUMACYTE COM Put 73,300 -25.81 128 -38.35 n/a n/a n/a
2025-08-14 2025-06-30 13F HUMACYTE COM Put 98,800 -30.81 206 -15.23 n/a n/a n/a
2025-05-15 2025-03-31 13F HUMACYTE COM Put 142,800 -51.46 243 -83.64 n/a n/a n/a
2025-02-14 2024-12-31 13F HUMACYTE COM Put 294,200 -3.48 1,486 -10.43 n/a n/a n/a
2024-11-14 2024-09-30 13F HUMACYTE COM Put 304,800 -29.38 1,658 -19.94 n/a n/a n/a
2024-08-14 2024-06-30 13F HUMACYTE COM Put 431,600 357.20 2,072 606.83 n/a n/a n/a
2024-05-15 2024-03-31 13F HUMACYTE COM Put 94,400 86.93 294 104.90 n/a n/a n/a
2024-02-14 2023-12-31 13F HUMACYTE COM Put 50,500 -19.84 143 -22.28 n/a n/a n/a
2023-11-14 2023-09-30 13F HUMACYTE COM Put 63,000 71.66 185 76.92 n/a n/a n/a
2023-08-14 2023-06-30 13F HUMACYTE COM Put 36,700 105 n/a n/a n/a
2023-05-15 2023-03-31 13F HUMACYTE COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2023-02-14 2022-12-31 13F HUMACYTE COM Put 14,900 31 n/a n/a n/a
2022-08-15 2022-06-30 13F HUMACYTE COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2022-05-16 2022-03-31 13F HUMACYTE COM Put 19,100 -47.53 135 -48.86 n/a n/a n/a
2022-02-14 2021-12-31 13F HUMACYTE COM Put 36,400 -52.48 264 -70.30 n/a n/a n/a
2021-11-15 2021-09-30 13F HUMACYTE Cmn Put 76,600 889 n/a n/a n/a
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.