Guardant Health, Inc.
US ˙ NasdaqGS ˙ US40131M1099

SecurityGH / Guardant Health, Inc.
InstitutionTrexquant Investment LP
Latest Disclosed Ownership85,901 shares
Latest Disclosed Value $ 7,934,675
Trexquant Investment LP reports 68.65% decrease in ownership of GH / Guardant Health, Inc.

On May 15, 2026 - Trexquant Investment LP filed a 13F-HR form disclosing ownership of 85,901 shares of Guardant Health, Inc. (US:GH) valued at $7,934,675 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 274,039 shares of Guardant Health, Inc.. This represents a change in shares of -68.65% during the quarter. The current value of the position is $10,790,025 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F GUARDANT HEALTH COM 40131M109 85,901 -188,138 -68.65 7,935 -71.65 0.0570
2026-02-17 2025-12-31 13F GUARDANT HEALTH COM 40131M109 274,039 -110,691 -28.77 27,990 16.45 0.2495
2025-11-14 2025-09-30 13F GUARDANT HEALTH COM 40131M109 384,730 8,025 2.13 24,038 22.62 0.2475
2025-08-12 2025-06-30 13F GUARDANT HEALTH COM 40131M109 376,705 196,315 108.83 19,604 155.11 0.2211
2025-05-14 2025-03-31 13F GUARDANT HEALTH COM 40131M109 180,390 -293,781 -61.96 7,685 -46.95 0.0894
2025-02-12 2024-12-31 13F GUARDANT HEALTH COM 40131M109 474,171 18,461 4.05 14,486 38.57 0.1688
2024-11-12 2024-09-30 13F GUARDANT HEALTH COM 40131M109 455,710 -129,204 -22.09 10,454 -38.12 0.1323
2024-08-13 2024-06-30 13F GUARDANT HEALTH COM 40131M109 584,914 312,418 114.65 16,892 200.52 0.2577
2024-05-14 2024-03-31 13F GUARDANT HEALTH COM 40131M109 272,496 48,849 21.84 5,622 -7.08 0.1121
2024-02-09 2023-12-31 13F GUARDANT HEALTH COM 40131M109 223,647 -4,097 -1.80 6,050 -10.39 0.1361
2023-11-13 2023-09-30 13F GUARDANT HEALTH COM 40131M109 227,744 -3,849 -1.66 6,750 -18.59 0.1694
2023-08-11 2023-06-30 13F GUARDANT HEALTH COM 40131M109 231,593 139,384 151.16 8,291 283.66 0.2173
2023-05-15 2023-03-31 13F GUARDANT HEALTH COM 40131M109 92,209 92,209 2,161 0.0594
2023-02-13 2022-12-31 13F GUARDANT HEALTH COM 40131M109 0 -17,746 -100.00 0 -100.00
2022-11-14 2022-09-30 13F GUARDANT HEALTH COM 40131M109 17,746 17,746 955 0.0336
2022-05-13 2022-03-31 13F GUARDANT HEALTH COM 40131M109 0 -11,823 -100.00 0 -100.00
2022-02-14 2021-12-31 13F GUARDANT HEALTH COM 40131M109 11,823 11,823 1,183 0.0731
2021-11-12 2021-09-30 13F GUARDANT HEALTH COM 40131M109 0 -26,329 -100.00 0 -100.00
2021-08-12 2021-06-30 13F GUARDANT HEALTH COM 40131M109 26,329 26,329 3,270 0.2759
2021-05-13 2021-03-31 13F GUARDANT HEALTH COM 40131M109 0 -7,741 -100.00 0 -100.00
2021-02-11 2020-12-31 13F GUARDANT HEALTH COM 40131M109 7,741 7,741 998 0.1057
2020-02-12 2019-12-31 13F GUARDANT HEALTH COM 40131M109 0 -15,892 -100.00 0 -100.00
2020-02-18 2019-09-30 13F/A-1 GUARDANT HEALTH COM 40131M109 15,892 15,892 1,014 0.0876
2019-11-08 2019-09-30 13F GUARDANT HEALTH COM 40131M109 15,892 1,014 0.0876
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.