Guardant Health, Inc.
US ˙ NasdaqGS ˙ US40131M1099

SecurityGH / Guardant Health, Inc.
InstitutionSignaturefd, Llc
Latest Disclosed Ownership785 shares
Latest Disclosed Value $ 72,510
Signaturefd, Llc reports 0.51% decrease in ownership of GH / Guardant Health, Inc.

On April 7, 2026 - Signaturefd, Llc filed a 13F-HR form disclosing ownership of 785 shares of Guardant Health, Inc. (US:GH) valued at $72,510 USD as of March 31, 2026. The entity filed a previous 13F-HR on January 20, 2026 disclosing 789 shares of Guardant Health, Inc.. This represents a change in shares of -0.51% during the quarter. The current value of the position is $98,604 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-04-07 2026-03-31 13F GUARDANT HEALTH COM 40131M109 785 -4 -0.51 73 -10.00 0.0011
2026-01-20 2025-12-31 13F GUARDANT HEALTH COM 40131M109 789 -112 -12.43 81 42.86 0.0012
2025-10-21 2025-09-30 13F GUARDANT HEALTH COM 40131M109 901 266 41.89 56 69.70 0.0009
2025-07-16 2025-06-30 13F GUARDANT HEALTH COM 40131M109 635 213 50.47 33 94.12 0.0006
2025-05-02 2025-03-31 13F GUARDANT HEALTH COM 40131M109 422 -341 -44.69 18 -26.09 0.0003
2025-02-10 2024-12-31 13F GUARDANT HEALTH COM 40131M109 763 39 5.39 23 43.75 0.0004
2024-10-21 2024-09-30 13F GUARDANT HEALTH COM 40131M109 724 344 90.53 17 60.00 0.0003
2024-07-29 2024-06-30 13F GUARDANT HEALTH COM 40131M109 380 206 118.39 11 233.33 0.0002
2024-05-03 2024-03-31 13F GUARDANT HEALTH COM 40131M109 174 -38 -17.92 4 -40.00 0.0001
2024-02-01 2023-12-31 13F GUARDANT HEALTH COM 40131M109 212 -291 -57.85 6 -64.29 0.0001
2023-11-03 2023-09-30 13F GUARDANT HEALTH COM 40131M109 503 46 10.07 15 -12.50 0.0004
2023-08-01 2023-06-30 13F GUARDANT HEALTH COM 40131M109 457 342 297.39 16 700.00 0.0004
2023-04-28 2023-03-31 13F GUARDANT HEALTH COM 40131M109 115 -283 -71.11 3 -80.00 0.0001
2023-01-30 2022-12-31 13F GUARDANT HEALTH COM 40131M109 398 14 3.65 11 -52.38 0.0003
2022-11-08 2022-09-30 13F GUARDANT HEALTH COM 40131M109 384 79 25.90 21 75.00 0.0007
2022-08-10 2022-06-30 13F GUARDANT HEALTH COM 40131M109 305 -33 -9.76 12 -45.45 0.0004
2022-05-02 2022-03-31 13F GUARDANT HEALTH COM 40131M109 338 88 35.20 22 -12.00 0.0007
2022-01-25 2021-12-31 13F GUARDANT HEALTH COM 40131M109 250 -119 -32.25 25 -45.65 0.0008
2021-10-28 2021-09-30 13F GUARDANT HEALTH COM 40131M109 369 130 54.39 46 53.33 0.0016
2021-07-26 2021-06-30 13F GUARDANT HEALTH COM 40131M109 239 60 33.52 30 11.11 0.0012
2021-04-30 2021-03-31 13F GUARDANT HEALTH COM 40131M109 179 6 3.47 27 22.73 0.0012
2021-02-11 2020-12-31 13F GUARDANT HEALTH COM 40131M109 173 -15 -7.98 22 4.76 0.0010
2020-11-03 2020-09-30 13F GUARDANT HEALTH COM 40131M109 188 -81 -30.11 21 -4.55 0.0011
2020-07-30 2020-06-30 13F GUARDANT HEALTH COM 40131M109 269 19 7.60 22 29.41 0.0013
2020-04-23 2020-03-31 13F GUARDANT HEALTH COM 40131M109 250 164 190.70 17 142.86 0.0015
2020-02-05 2019-12-31 13F GUARDANT HEALTH COM 40131M109 86 -1 -1.15 7 16.67 0.0005
2019-10-16 2019-09-30 13F GUARDANT HEALTH COM 40131M109 87 0 0.00 6 -25.00 0.0005
2019-07-31 2019-06-30 13F GUARDANT HEALTH COM 40131M109 87 1 1.16 8 14.29 0.0007
2019-05-09 2019-03-31 13F GUARDANT HEALTH COM 40131M109 86 86 7 0.0006
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.