Exelixis, Inc.
US ˙ NasdaqGS ˙ US30161Q1040

SecurityEXEL / Exelixis, Inc.
InstitutionSignaturefd, Llc
Latest Disclosed Ownership6,054 shares
Latest Disclosed Value $ 259,656
Signaturefd, Llc reports 9.06% decrease in ownership of EXEL / Exelixis, Inc.

On April 7, 2026 - Signaturefd, Llc filed a 13F-HR form disclosing ownership of 6,054 shares of Exelixis, Inc. (US:EXEL) valued at $259,656 USD as of March 31, 2026. The entity filed a previous 13F-HR on January 20, 2026 disclosing 6,657 shares of Exelixis, Inc.. This represents a change in shares of -9.06% during the quarter. The current value of the position is $319,046 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-04-07 2026-03-31 13F EXELIXIS COM 30161Q104 6,054 -603 -9.06 260 -11.00 0.0040
2026-01-20 2025-12-31 13F EXELIXIS COM 30161Q104 6,657 -143 -2.10 292 3.93 0.0045
2025-10-21 2025-09-30 13F EXELIXIS COM 30161Q104 6,800 -387 -5.38 281 -11.39 0.0044
2025-07-16 2025-06-30 13F EXELIXIS COM 30161Q104 7,187 56 0.79 317 20.15 0.0054
2025-05-02 2025-03-31 13F EXELIXIS COM 30161Q104 7,131 172 2.47 263 13.85 0.0050
2025-02-10 2024-12-31 13F EXELIXIS COM 30161Q104 6,959 821 13.38 232 45.28 0.0044
2024-10-21 2024-09-30 13F EXELIXIS COM 30161Q104 6,138 666 12.17 159 30.33 0.0030
2024-07-29 2024-06-30 13F EXELIXIS COM 30161Q104 5,472 2,169 65.67 123 56.41 0.0025
2024-05-03 2024-03-31 13F EXELIXIS COM 30161Q104 3,303 140 4.43 78 4.00 0.0017
2024-02-01 2023-12-31 13F EXELIXIS COM 30161Q104 3,163 -1,414 -30.89 76 -25.00 0.0018
2023-11-03 2023-09-30 13F EXELIXIS COM 30161Q104 4,577 668 17.09 100 35.14 0.0026
2023-08-01 2023-06-30 13F EXELIXIS COM 30161Q104 3,909 -10 -0.26 75 -2.63 0.0019
2023-04-28 2023-03-31 13F EXELIXIS COM 30161Q104 3,919 1,152 41.63 76 72.73 0.0021
2023-01-30 2022-12-31 13F EXELIXIS COM 30161Q104 2,767 619 28.82 44 29.41 0.0013
2022-11-08 2022-09-30 13F EXELIXIS COM 30161Q104 2,148 1,719 400.70 34 277.78 0.0012
2022-08-10 2022-06-30 13F EXELIXIS COM 30161Q104 429 218 103.32 9 80.00 0.0003
2022-05-02 2022-03-31 13F EXELIXIS COM 30161Q104 211 62 41.61 5 66.67 0.0002
2022-01-25 2021-12-31 13F EXELIXIS COM 30161Q104 149 120 413.79 3 200.00 0.0001
2021-10-28 2021-09-30 13F EXELIXIS COM 30161Q104 29 -158 -84.49 1 -66.67 0.0000
2021-07-26 2021-06-30 13F EXELIXIS COM 30161Q104 187 94 101.08 3 50.00 0.0001
2021-04-30 2021-03-31 13F EXELIXIS COM 30161Q104 93 50 116.28 2 100.00 0.0001
2021-02-11 2020-12-31 13F EXELIXIS COM 30161Q104 43 -96 -69.06 1 -66.67 0.0000
2020-11-03 2020-09-30 13F EXELIXIS COM 30161Q104 139 66 90.41 3 50.00 0.0002
2020-07-30 2020-06-30 13F EXELIXIS COM 30161Q104 73 -186 -71.81 2 -50.00 0.0001
2020-04-23 2020-03-31 13F EXELIXIS COM 30161Q104 259 43 19.91 4 0.00 0.0003
2020-02-05 2019-12-31 13F EXELIXIS COM 30161Q104 216 -1,487 -87.32 4 -86.67 0.0003
2019-10-16 2019-09-30 13F EXELIXIS COM 30161Q104 1,703 -584 -25.54 30 -38.78 0.0025
2019-07-31 2019-06-30 13F EXELIXIS COM 30161Q104 2,287 2,079 999.52 49 880.00 0.0042
2019-05-09 2019-03-31 13F EXELIXIS COM 30161Q104 208 0 0.00 5 25.00 0.0004
2019-02-13 2018-12-31 13F EXELIXIS COM 30161Q104 208 76 57.58 4 100.00 0.0004
2018-11-14 2018-09-30 13F EXELIXIS COM 30161Q104 132 2 1.54 2 -33.33 0.0002
2018-08-14 2018-06-30 13F EXELIXIS COM 30161Q104 130 20 18.18 3 50.00 0.0003
2018-05-08 2018-03-31 13F EXELIXIS COM 30161Q104 110 110 2 0.0002
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.