Design Therapeutics, Inc.
US ˙ NasdaqGS ˙ US25056L1035

SecurityDSGN / Design Therapeutics, Inc.
InstitutionDimensional Fund Advisors Lp
Latest Disclosed Ownership431,840 shares
Latest Disclosed Value $ 4,593,449
Dimensional Fund Advisors Lp reports 44.95% increase in ownership of DSGN / Design Therapeutics, Inc.

On May 7, 2026 - Dimensional Fund Advisors Lp filed a 13F-HR form disclosing ownership of 431,840 shares of Design Therapeutics, Inc. (US:DSGN) valued at $4,594,778 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 297,921 shares of Design Therapeutics, Inc.. This represents a change in shares of 44.95% during the quarter. The current value of the position is $4,508,410 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-07 2026-03-31 13F DESIGN THERAPEUTICS COM 25056L103 431,840 133,919 44.95 4,593 64.33 0.0002
2026-02-12 2025-12-31 13F DESIGN THERAPEUTICS COM 25056L103 297,921 18,104 6.47 2,795 32.78 0.0006
2025-11-12 2025-09-30 13F DESIGN THERAPEUTICS COM 25056L103 279,817 -33,546 -10.71 2,105 99.34 0.0005
2025-08-12 2025-06-30 13F DESIGN THERAPEUTICS COM 25056L103 313,363 24,761 8.58 1,057 -5.21 0.0002
2025-05-13 2025-03-31 13F DESIGN THERAPEUTICS COM 25056L103 288,602 73,337 34.07 1,115 -16.11 0.0003
2025-02-13 2024-12-31 13F DESIGN THERAPEUTICS COM 25056L103 215,265 80,905 60.22 1,328 83.93 0.0003
2024-11-07 2024-09-30 13F DESIGN THERAPEUTICS COM 25056L103 134,360 53,407 65.97 723 166.42 0.0002
2024-08-09 2024-06-30 13F DESIGN THERAPEUTICS COM 25056L103 80,953 44,098 119.65 271 83.11 0.0001
2024-05-10 2024-03-31 13F DESIGN THERAPEUTICS COM 25056L103 36,855 -4,993 -11.93 149 33.33 0.0000
2024-02-07 2023-12-31 13F DESIGN THERAPEUTICS COM 25056L103 41,848 -12,267 -22.67 111 -12.60 0.0000
2023-11-09 2023-09-30 13F DESIGN THERAPEUTICS COM 25056L103 54,115 -5,520 -9.26 128 -66.04 0.0000
2023-08-09 2023-06-30 13F DESIGN THERAPEUTICS COM 25056L103 59,635 -16,850 -22.03 375 -15.19 0.0001
2023-05-12 2023-03-31 13F DESIGN THERAPEUTICS COM 25056L103 76,485 -77,635 -50.37 441 44,000.00 0.0001
2023-02-09 2022-12-31 13F DESIGN THERAPEUTICS COM 25056L103 154,120 25,248 19.59 2 -99.95 0.0005
2022-11-10 2022-09-30 13F DESIGN THERAPEUTICS COM 25056L103 128,872 100,728 357.90 2,156 447.21 0.0008
2022-08-12 2022-06-30 13F DESIGN THERAPEUTICS COM 25056L103 28,144 28,144 394 0.0001
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.