Denali Therapeutics Inc.
US ˙ NasdaqGS ˙ US24823R1059

SecurityDNLI / Denali Therapeutics Inc.
InstitutionTrexquant Investment LP
Latest Disclosed Ownership0 shares
Latest Disclosed Value $ 0
Trexquant Investment LP closes position in DNLI / Denali Therapeutics Inc.

On May 15, 2026 - Trexquant Investment LP filed a 13F-HR form disclosing ownership of 0 shares of Denali Therapeutics Inc. (US:DNLI) valued at $0 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 209,609 shares of Denali Therapeutics Inc.. The current value of the position is $0 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F DENALI THERAPEUTICS COM 24823R105 0 -100.00 0
2026-02-17 2025-12-31 13F DENALI THERAPEUTICS COM 24823R105 209,609 -220,957 -51.32 3,461 -44.65 0.0309
2025-11-14 2025-09-30 13F DENALI THERAPEUTICS COM 24823R105 430,566 321,324 294.14 6,252 309.10 0.0644
2025-08-12 2025-06-30 13F DENALI THERAPEUTICS COM 24823R105 109,242 -3,982 -3.52 1,528 -0.71 0.0172
2025-05-14 2025-03-31 13F DENALI THERAPEUTICS COM 24823R105 113,224 52,568 86.67 1,539 24.51 0.0179
2025-02-12 2024-12-31 13F DENALI THERAPEUTICS COM 24823R105 60,656 36,122 147.23 1,236 73.11 0.0144
2024-11-12 2024-09-30 13F DENALI THERAPEUTICS COM 24823R105 24,534 24,534 715 0.0090
2024-02-09 2023-12-31 13F DENALI THERAPEUTICS COM 24823R105 0 -42,349 -100.00 0 -100.00
2023-11-13 2023-09-30 13F DENALI THERAPEUTICS COM 24823R105 42,349 -24,586 -36.73 874 -55.80 0.0219
2023-08-11 2023-06-30 13F DENALI THERAPEUTICS COM 24823R105 66,935 -13,589 -16.88 1,975 6.47 0.0518
2023-05-15 2023-03-31 13F DENALI THERAPEUTICS COM 24823R105 80,524 57,669 252.33 1,855 192.13 0.0510
2023-02-13 2022-12-31 13F DENALI THERAPEUTICS COM 24823R105 22,855 -2,774 -10.82 636 -19.31 0.0180
2022-11-14 2022-09-30 13F DENALI THERAPEUTICS COM 24823R105 25,629 25,629 787 0.0277
2021-08-12 2021-06-30 13F DENALI THERAPEUTICS COM 24823R105 0 -16,192 -100.00 0 -100.00
2021-05-13 2021-03-31 13F DENALI THERAPEUTICS COM 24823R105 16,192 16,192 925 0.0849
2021-02-11 2020-12-31 13F DENALI THERAPEUTICS COM 24823R105 0 -40,025 -100.00 0 -100.00
2020-11-06 2020-09-30 13F DENALI THERAPEUTICS COM 24823R105 40,025 40,025 1,434 0.0923
2018-11-09 2018-09-30 13F DENALI THERAPEUTICS COM 24823R105 0 -10,151 -100.00 0 -100.00
2018-08-07 2018-06-30 13F DENALI THERAPEUTICS COM 24823R105 10,151 10,151 155 0.0107
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.