Denali Therapeutics Inc.
US ˙ NasdaqGS ˙ US24823R1059

SecurityDNLI / Denali Therapeutics Inc.
InstitutionAssetmark, Inc
Latest Disclosed Ownership5,199 shares
Latest Disclosed Value $ 99,821
Assetmark, Inc reports 0.23% increase in ownership of DNLI / Denali Therapeutics Inc.

On May 6, 2026 - Assetmark, Inc filed a 13F-HR form disclosing ownership of 5,199 shares of Denali Therapeutics Inc. (US:DNLI) valued at $99,821 USD as of March 31, 2026. The entity filed a previous 13F-HR on January 23, 2026 disclosing 5,187 shares of Denali Therapeutics Inc.. This represents a change in shares of 0.23% during the quarter. The current value of the position is $102,212 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-06 2026-03-31 13F DENALI THERAPEUTICS COM 24823R105 5,199 12 0.23 100 16.47 0.0002
2026-01-23 2025-12-31 13F DENALI THERAPEUTICS COM 24823R105 5,187 1,250 31.75 86 49.12 0.0002
2025-11-06 2025-09-30 13F DENALI THERAPEUTICS COM 24823R105 3,937 317 8.76 57 14.00 0.0001
2025-08-04 2025-06-30 13F DENALI THERAPEUTICS COM 24823R105 3,620 435 13.66 51 16.28 0.0001
2025-05-06 2025-03-31 13F DENALI THERAPEUTICS COM 24823R105 3,185 -494 -13.43 43 -41.89 0.0001
2025-02-06 2024-12-31 13F DENALI THERAPEUTICS COM 24823R105 3,679 -129 -3.39 75 -32.73 0.0002
2024-11-01 2024-09-30 13F DENALI THERAPEUTICS COM 24823R105 3,808 580 17.97 111 48.65 0.0003
2024-08-13 2024-06-30 13F DENALI THERAPEUTICS COM 24823R105 3,228 -86 -2.60 75 8.82 0.0002
2024-05-07 2024-03-31 13F DENALI THERAPEUTICS COM 24823R105 3,314 -236 -6.65 68 -10.53 0.0002
2024-02-09 2023-12-31 13F DENALI THERAPEUTICS COM 24823R105 3,550 1,402 65.27 76 72.73 0.0003
2023-10-27 2023-09-30 13F DENALI THERAPEUTICS COM 24823R105 2,148 707 49.06 44 4.76 0.0002
2023-08-11 2023-06-30 13F DENALI THERAPEUTICS INC COM COM 24823R105 1,441 669 86.66 43 147.06 0.0002
2023-05-05 2023-03-31 13F DENALI THERAPEUTICS INC COM COM 24823R105 772 198 34.49 18 13.33 0.0001
2023-02-10 2022-12-31 13F DENALI THERAPEUTICS COM 24823R105 574 136 31.05 16 15.38 0.0001
2022-11-01 2022-09-30 13F DENALI THERAPEUTICS COM 24823R105 438 438 13 0.0001
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.