Blueprint Medicines Corporation
US ˙ NasdaqGS ˙ US09627Y1091
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SecurityBPMC / Blueprint Medicines Corporation
InstitutionWalleye Capital LLC
Latest Disclosed Ownership0 shares
Latest Disclosed Value $ 0
Walleye Capital LLC ownership in BPMC / Blueprint Medicines Corporation

On November 14, 2025 - Walleye Capital LLC filed a 13F-HR form disclosing ownership of 0 shares of Blueprint Medicines Corporation (US:BPMC) valued at $0 USD as of September 30, 2025. The entity filed a previous 13F-HR on August 13, 2025 disclosing 16,830 shares of Blueprint Medicines Corporation. The current value of the position is $0 USD.

Walleye Capital LLC has a history of taking positions in derivatives of the underlying security (BPMC) in the form of stock options. The firm currently holds call options representing 0 of underlying shares valued at $0 USD and put options representing 0 of underlying shares valued at $0 USD .

Note: prior versions of this page mistakenly stated that the share values represented the number of options, not the number of underlying shares. For more information on the data backing these reports, please see the SEC document Frequently Asked Questions About Form 13F.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Institutional Put/Call Ratios
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In addition to reporting standard equity and debt issues, institutions with more than 100MM assets under management must also disclose their put and call option holdings. Since put options generally indicate negative sentiment, and call options indicate positive sentiment, we can get a sense of the overall institutional sentiment by plotting the ratio of puts to calls. The chart to the right plots the historical put/call ratio for this instrument.

Using Put/Call Ratio as an indicator of investor sentiment overcomes one of the key deficiencies of using total institutional ownership, which is that a significant amount of assets under management are invested passively to track indices. Passively-managed funds do not typically buy options, so the put/call ratio indicator more closely tracks the sentiment of actively-managed funds.

BPMC / Blueprint Medicines Corporation Historical Put/Call Ratio
Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2025-11-14 2025-09-30 13F BLUEPRINT MEDICINES COM 09627Y109 0 -100.00 0
2025-08-13 2025-06-30 13F BLUEPRINT MEDICINES COM 09627Y109 16,830 -25,365 -60.11 2,157 -42.23 0.0084
2025-05-14 2025-03-31 13F BLUEPRINT MEDICINES COM 09627Y109 42,195 14,305 51.29 3,735 53.54 0.0169
2025-02-13 2024-12-31 13F BLUEPRINT MEDICINES COM 09627Y109 27,890 24,641 758.42 2,433 710.67 0.0059
2024-11-14 2024-09-30 13F BLUEPRINT MEDICINES COM 09627Y109 3,249 -6,495 -66.66 301 -71.43 0.0006
2024-08-14 2024-06-30 13F BLUEPRINT MEDICINES COM 09627Y109 9,744 8,156 513.60 1,050 600.00 0.0019
2024-05-15 2024-03-31 13F BLUEPRINT MEDICINES COM 09627Y109 1,588 1,588 151 0.0003
2022-11-14 2022-09-30 13F BLUEPRINT MEDICINES COM 09627Y109 0 -5,234 -100.00 0 -100.00
2022-08-19 2022-06-30 13F/A-1 BLUEPRINT MEDICINES COM 09627Y109 5,234 5,234 264 0.0073
2022-08-08 2022-06-30 13F BLUEPRINT MEDICINES COM 09627Y109 5,234 5,234 264 0.0073
2022-05-27 2022-03-31 13F/A-01 BLUEPRINT MEDICINES COM 09627Y109 0 -15,461 -100.00 0 -100.00
2022-05-16 2022-03-31 13F BLUEPRINT MEDICINES COM 09627Y109 0 -15,461 0
2022-05-27 2021-12-31 13F/A-01 BLUEPRINT MEDICINES COM 09627Y109 15,461 15,461 1,656 0.0514
2022-03-03 2021-12-31 13F BLUEPRINT MEDICINES COM 09627Y109 15,461 15,461 1,656 0.0414
2020-11-16 2020-09-30 13F BLUEPRINT MEDICINES COM 09627Y109 0 -2,628 -100.00 0 -100.00
2020-08-14 2020-06-30 13F BLUEPRINT MEDICINES COM 09627Y109 2,628 2,628 205 0.0457
Disclosed Call Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share
Price
Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2025-11-14 2025-09-30 13F BLUEPRINT MEDICINES COM Call 0 -100.00 0 n/a n/a n/a
2025-08-13 2025-06-30 13F BLUEPRINT MEDICINES COM Call 500 150.00 64 276.47 n/a n/a n/a
2025-05-14 2025-03-31 13F BLUEPRINT MEDICINES COM Call 200 0.00 18 0.00 n/a n/a n/a
2025-02-13 2024-12-31 13F BLUEPRINT MEDICINES COM Call 200 -97.06 17 -97.30 n/a n/a n/a
2024-11-14 2024-09-30 13F BLUEPRINT MEDICINES COM Call 6,800 -73.02 629 -76.84 n/a n/a n/a
2024-08-14 2024-06-30 13F BLUEPRINT MEDICINES COM Call 25,200 227.27 2,716 272.05 n/a n/a n/a
2024-05-15 2024-03-31 13F BLUEPRINT MEDICINES COM Call 7,700 730 n/a n/a n/a
2023-11-21 2023-09-30 13F/A BLUEPRINT MEDICINES COM Call 0 -100.00 0 -100.00 n/a n/a n/a
2023-11-14 2023-09-30 13F BLUEPRINT MEDICINES COM Call 0 0 n/a n/a n/a
2023-08-14 2023-06-30 13F BLUEPRINT MEDICINES COM Call 2,300 -73.56 145 -62.92 n/a n/a n/a
2023-05-15 2023-03-31 13F BLUEPRINT MEDICINES COM Call 8,700 171.88 391 179.29 n/a n/a n/a
2023-02-14 2022-12-31 13F BLUEPRINT MEDICINES COM Call 3,200 140 n/a n/a n/a
2020-08-14 2020-06-30 13F BLUEPRINT MEDICINES COM Call 0 -100.00 0 -100.00 n/a n/a n/a
2020-05-15 2020-03-31 13F BLUEPRINT MEDICINES COM Call 7,200 -25.77 421 -45.82 n/a n/a n/a
2020-02-14 2019-12-31 13F BLUEPRINT MEDICINES COM Call 9,700 12.79 777 22.94 n/a n/a n/a
2019-11-14 2019-09-30 13F BLUEPRINT MEDICINES COM Call 8,600 632 n/a n/a n/a
Disclosed Put Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share Price Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2025-11-14 2025-09-30 13F BLUEPRINT MEDICINES COM Put 0 -100.00 0 n/a n/a n/a
2025-08-13 2025-06-30 13F BLUEPRINT MEDICINES COM Put 700 -36.36 90 -8.25 n/a n/a n/a
2025-05-14 2025-03-31 13F BLUEPRINT MEDICINES COM Put 1,100 97 n/a n/a n/a
2025-02-13 2024-12-31 13F BLUEPRINT MEDICINES COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2024-11-14 2024-09-30 13F BLUEPRINT MEDICINES COM Put 11,700 -64.97 1,082 -69.94 n/a n/a n/a
2024-08-14 2024-06-30 13F BLUEPRINT MEDICINES COM Put 33,400 178.33 3,600 216.26 n/a n/a n/a
2024-05-15 2024-03-31 13F BLUEPRINT MEDICINES COM Put 12,000 1,138 n/a n/a n/a
2023-11-21 2023-09-30 13F/A BLUEPRINT MEDICINES COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2023-11-14 2023-09-30 13F BLUEPRINT MEDICINES COM Put 0 0 n/a n/a n/a
2023-08-14 2023-06-30 13F BLUEPRINT MEDICINES COM Put 1,600 -81.40 101 -73.83 n/a n/a n/a
2023-05-15 2023-03-31 13F BLUEPRINT MEDICINES COM Put 8,600 86.96 387 92.04 n/a n/a n/a
2023-02-14 2022-12-31 13F BLUEPRINT MEDICINES COM Put 4,600 202 n/a n/a n/a
2020-08-14 2020-06-30 13F BLUEPRINT MEDICINES COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2020-05-15 2020-03-31 13F BLUEPRINT MEDICINES COM Put 1,200 -81.82 70 -86.77 n/a n/a n/a
2020-02-14 2019-12-31 13F BLUEPRINT MEDICINES COM Put 6,600 529 n/a n/a n/a
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.