Biomea Fusion, Inc.
US ˙ NasdaqGS ˙ US09077A1060

SecurityBMEA / Biomea Fusion, Inc.
InstitutionMorgan Stanley
Latest Disclosed Ownership346,742 shares
Latest Disclosed Value $ 530,516
Morgan Stanley reports 6.95% decrease in ownership of BMEA / Biomea Fusion, Inc.

On May 15, 2026 - Morgan Stanley filed a 13F-HR form disclosing ownership of 346,742 shares of Biomea Fusion, Inc. (US:BMEA) valued at $530,515 USD as of March 31, 2026. The entity filed a previous 13F-HR/A on May 27, 2026 disclosing 372,629 shares of Biomea Fusion, Inc.. This represents a change in shares of -6.95% during the quarter. The current value of the position is $450,765 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F BIOMEA FUSION COM 09077A106 346,742 -25,887 -6.95 531 14.72 0.0000
2026-05-27 2025-12-31 13F/A-1 BIOMEA FUSION COM 09077A106 372,629 -70,429 -15.90 462 -48.32 0.0000
2026-02-13 2025-12-31 13F BIOMEA FUSION COM 09077A106 372,629 -70,429 462 0.0000
2026-05-27 2025-09-30 13F/A-1 BIOMEA FUSION COM 09077A106 443,058 56,534 14.63 895 28.63 0.0001
2025-11-14 2025-09-30 13F BIOMEA FUSION COM 09077A106 443,058 56,534 895 0.0001
2025-08-15 2025-06-30 13F BIOMEA FUSION COM 09077A106 386,524 -93,556 -19.49 696 -32.00 0.0000
2025-05-15 2025-03-31 13F BIOMEA FUSION COM 09077A106 480,080 17,722 3.83 1,023 -43.00 0.0001
2025-05-15 2024-12-31 13F/A-1 BIOMEA FUSION COM 09077A106 462,358 -44,453 -8.77 1,794 -64.97 0.0001
2025-02-14 2024-12-31 13F BIOMEA FUSION COM 09077A106 462,358 -44,453 1,794 0.0001
2025-05-14 2024-09-30 13F/A-2 BIOMEA FUSION COM 09077A106 506,811 39,866 8.54 5,119 143.60 0.0004
2025-02-14 2024-09-30 13F/A-1 BIOMEA FUSION COM 09077A106 506,811 39,866 5,119 0.0004
2024-11-14 2024-09-30 13F BIOMEA FUSION COM 09077A106 506,811 39,866 5,119 0.0000
2025-05-14 2024-06-30 13F/A-2 BIOMEA FUSION COM 09077A106 466,945 9,524 2.08 2,101 -69.27 0.0002
2024-10-17 2024-06-30 13F/A-1 BIOMEA FUSION COM 09077A106 466,945 9,524 2,101 0.0002
2024-08-14 2024-06-30 13F BIOMEA FUSION COM 09077A106 466,945 9,524 2,101 0.0002
2024-10-17 2024-03-31 13F/A-2 BIOMEA FUSION COM 09077A106 457,421 -20,981 -4.39 6,838 -1.55 0.0005
2024-08-16 2024-03-31 13F/A-1 BIOMEA FUSION COM 09077A106 457,421 -20,981 6,838 0.0001
2024-05-15 2024-03-31 13F BIOMEA FUSION COM 09077A106 457,421 -20,981 6,838 0.0005
2024-08-16 2023-12-31 13F/A-1 BIOMEA FUSION COM 09077A106 478,402 246,937 106.68 6,946 118.15 0.0006
2024-02-13 2023-12-31 13F BIOMEA FUSION COM 09077A106 478,402 246,937 6,946 0.0006
2023-11-15 2023-09-30 13F BIOMEA FUSION COM 09077A106 231,465 120,223 108.07 3,185 30.44 0.0003
2023-08-14 2023-06-30 13F BIOMEA FUSION COM 09077A106 111,242 -5,979 -5.10 2,442 -32.85 0.0002
2023-05-15 2023-03-31 13F BIOMEA FUSION COM 09077A106 117,221 1,017 0.88 3,635 271.30 0.0004
2023-02-14 2022-12-31 13F BIOMEA FUSION COM 09077A106 116,204 12,979 12.57 980 -2.97 0.0001
2022-11-14 2022-09-30 13F BIOMEA FUSION COM 09077A106 103,225 -18,084 -14.91 1,009 -30.61 0.0001
2022-10-27 2022-06-30 13F/A-1 BIOMEA FUSION COM 09077A106 121,309 102,949 560.72 1,454 1,673.17 0.0002
2022-08-15 2022-06-30 13F BIOMEA FUSION COM 09077A106 121,309 102,949 1,454 0.0000
2022-10-27 2022-03-31 13F/A-1 BIOMEA FUSION COM 09077A106 18,360 -8,669 -32.07 82 -59.20 0.0000
2022-05-13 2022-03-31 13F BIOMEA FUSION COM 09077A106 18,360 -8,669 82 0.0000
2022-02-14 2021-12-31 13F BIOMEA FUSION COM 09077A106 27,029 18,374 212.29 201 95.15 0.0000
2021-11-15 2021-09-30 13F BIOMEA FUSION COM 09077A106 8,655 141 1.66 103 -22.56 0.0000
2021-08-23 2021-06-30 13F/A-1 BIOMEA FUSION COM 09077A106 8,514 8,514 133 0.0000
2021-08-16 2021-06-30 13F BIOMEA FUSION COM 09077A106 8,514 8,514 133 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.