Arrowhead Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US04280A1007

SecurityARWR / Arrowhead Pharmaceuticals, Inc.
InstitutionDimensional Fund Advisors Lp
Latest Disclosed Ownership608,531 shares
Latest Disclosed Value $ 38,149,870
Dimensional Fund Advisors Lp reports 312.81% increase in ownership of ARWR / Arrowhead Pharmaceuticals, Inc.

On May 7, 2026 - Dimensional Fund Advisors Lp filed a 13F-HR form disclosing ownership of 608,531 shares of Arrowhead Pharmaceuticals, Inc. (US:ARWR) valued at $38,154,894 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 147,412 shares of Arrowhead Pharmaceuticals, Inc.. This represents a change in shares of 312.81% during the quarter. The current value of the position is $44,148,924 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-07 2026-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 608,531 461,119 312.81 38,150 289.83 0.0017
2026-02-12 2025-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 147,412 -327,050 -68.93 9,787 -40.20 0.0021
2025-11-12 2025-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 474,462 107,751 29.38 16,364 182.43 0.0035
2025-08-12 2025-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 366,711 366,711 5,794 0.0013
2025-05-13 2025-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 0 -35,666 -100.00 0 -100.00
2025-02-13 2024-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 35,666 -86,214 -70.74 671 -71.61 0.0002
2024-11-07 2024-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 121,880 -23,994 -16.45 2,361 -37.75 0.0006
2024-08-09 2024-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 145,874 84,867 139.11 3,791 117.37 0.0010
2024-05-10 2024-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 61,007 -486,779 -88.86 1,745 -89.60 0.0005
2024-02-07 2023-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 547,786 -140,125 -20.37 16,762 -9.32 0.0049
2023-11-09 2023-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 687,911 333,516 94.11 18,484 46.27 0.0061
2023-08-09 2023-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 354,395 354,395 12,638 0.0040
2023-05-12 2023-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 0 -16,759 -100.00 0 0.0000
2023-02-09 2022-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 16,759 0 0.00 1 -100.00 0.0002
2022-11-10 2022-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 16,759 -18,184 -52.04 554 -54.96 0.0002
2022-08-12 2022-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 34,943 -23,276 -39.98 1,230 -54.05 0.0004
2022-05-13 2022-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 58,219 -63,070 -52.00 2,677 -66.72 0.0008
2022-02-09 2021-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 121,289 -36,801 -23.28 8,043 -18.51 0.0024
2021-11-12 2021-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 158,090 -61,498 -28.01 9,870 -45.72 0.0032
2021-08-12 2021-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 219,588 6,512 3.06 18,184 28.76 0.0058
2021-05-14 2021-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 213,076 -19,224 -8.28 14,122 -20.78 0.0047
2021-03-08 2020-12-31 13F/A-2 ARROWHEAD PHARMACEUTICALS IN COM 04280A100 232,300 -95,715 -29.18 17,826 26.20 0.0064
2021-02-11 2020-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 232,300 -95,715 17,826 6,437.8037
2020-11-12 2020-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 328,015 29,957 10.05 14,125 9.74 0.0060
2020-08-13 2020-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 298,058 160,825 117.19 12,871 226.01 0.0057
2020-05-14 2020-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 137,233 -4,464 -3.15 3,948 -56.08 0.0021
2020-02-14 2019-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 141,697 99,687 237.29 8,990 659.29 0.0033
2019-11-12 2019-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 42,010 42,010 1,184 0.0005
2019-02-26 2018-12-31 13F/A-1 ARROWHEAD PHARMACEUTICALS IN COM 04280A100 0 -44,358 -100.00 0 -100.00
2018-11-13 2018-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 44,358 0 0.00 850 40.96 0.0003
2018-08-10 2018-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 44,358 0 0.00 603 88.44 0.0002
2018-05-11 2018-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 44,358 0 0.00 320 96.32 0.0001
2018-02-12 2017-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 44,358 0 0.00 163 -15.10 0.0001
2017-11-13 2017-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 44,358 31,765 252.24 192 860.00 0.0001
2017-08-11 2017-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 12,593 0 0.00 20 -13.04 0.0000
2017-05-12 2017-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 12,593 12,593 23 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.