Arvinas, Inc.
US ˙ NasdaqGS ˙ US04335A1051

SecurityARVN / Arvinas, Inc.
InstitutionNew Leaf Venture Partners, L.L.C.
Latest Disclosed Ownership1,585,721 shares
Latest Disclosed Value $ 13,510,343
New Leaf Venture Partners, L.L.C. ownership in ARVN / Arvinas, Inc.

On November 14, 2025 - New Leaf Venture Partners, L.L.C. filed a 13F-HR form disclosing ownership of 1,585,721 shares of Arvinas, Inc. (US:ARVN) valued at $13,510,343 USD as of September 30, 2025. The entity filed a previous 13F-HR on August 13, 2025 disclosing 1,585,721 shares of Arvinas, Inc.. This represents a change in shares of 0.00% during the quarter. The current value of the position is $11,766,050 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2025-11-14 2025-09-30 13F ARVN ARVINAS INC 04335A105 1,585,721 0 0.00 13,510 15.77 31.3845
2025-08-13 2025-06-30 13F ARVINAS COM 04335A105 1,585,721 0 0.00 11,671 4.84 22.0414
2025-05-13 2025-03-31 13F ARVINAS COM 04335A105 1,585,721 0 0.00 11,132 -63.38 24.7915
2025-02-13 2024-12-31 13F ARVINAS COM 04335A105 1,585,721 151,000 10.52 30,398 -13.98 40.6385
2024-11-13 2024-09-30 13F ARVINAS COM 04335A105 1,434,721 145,200 11.26 35,337 2.94 36.3195
2024-08-14 2024-06-30 13F ARVINAS COM 04335A105 1,289,521 0 0.00 34,327 -35.51 41.7413
2024-05-14 2024-03-31 13F ARVINAS COM 04335A105 1,289,521 0 0.00 53,231 0.29 46.5895
2024-02-14 2023-12-31 13F ARVINAS COM 04335A105 1,289,521 0 0.00 53,077 109.04 42.7520
2023-11-14 2023-09-30 13F ARVINAS COM 04335A105 1,289,521 0 0.00 25,391 -20.67 32.6043
2023-08-10 2023-06-30 13F ARVINAS COM 04335A105 1,289,521 0 0.00 32,006 -9.15 27.4875
2023-05-11 2023-03-31 13F ARVINAS COM 04335A105 1,289,521 0 0.00 35,230 -20.14 29.1116
2023-02-06 2022-12-31 13F ARVINAS COM 04335A105 1,289,521 0 0.00 44,115 -23.11 31.9367
2022-11-10 2022-09-30 13F ARVINAS COM 04335A105 1,289,521 0 0.00 57,371 5.70 34.0406
2022-08-09 2022-06-30 13F ARVINAS COM 04335A105 1,289,521 0 0.00 54,276 -37.46 35.1610
2022-05-06 2022-03-31 13F ARVINAS COM 04335A105 1,289,521 0 0.00 86,785 -18.07 42.7715
2022-02-11 2021-12-31 13F ARVINAS COM 04335A105 1,289,521 -18,666 -1.43 105,921 -1.48 38.3749
2021-11-12 2021-09-30 13F ARVINAS COM 04335A105 1,308,187 -904,561 -40.88 107,507 -36.90 31.0088
2021-08-12 2021-06-30 13F ARVINAS COM 04335A105 2,212,748 -70,300 -3.08 170,382 12.90 43.7329
2021-08-12 2021-03-31 13F/A-1 ARVINAS COM 04335A105 2,283,048 0 0.00 150,909 -22.17 35.1226
2021-05-12 2021-03-31 13F ARVINAS COM 04335A105 2,283,048 0 150,909 35.5296
2021-02-10 2020-12-31 13F ARVINAS COM 04335A105 2,283,048 0 0.00 193,899 259.72 44.7994
2020-11-12 2020-09-30 13F ARVINAS COM 04335A105 2,283,048 0 0.00 53,903 -29.61 21.7186
2020-08-13 2020-06-30 13F ARVINAS COM 04335A105 2,283,048 0 0.00 76,573 -16.77 21.9720
2020-05-14 2020-03-31 13F ARVINAS COM 04335A105 2,283,048 0 0.00 92,007 -1.92 27.5230
2020-02-13 2019-12-31 13F ARVINAS COM 04335A105 2,283,048 0 0.00 93,810 90.67 20.3805
2019-11-14 2019-09-30 13F ARVINAS COM 04335A105 2,283,048 0 0.00 49,200 -2.00 14.8814
2019-08-13 2019-06-30 13F ARVINAS COM 04335A105 2,283,048 0 0.00 50,204 48.98 13.4566
2019-06-04 2019-03-31 13F/A-1 ARVINAS COM 04335A105 2,283,048 0 0.00 33,698 14.87 9.2338
2019-05-15 2019-03-31 13F ARVINAS COM 04335A105 2,283,048 33,698
2019-02-13 2018-12-31 13F ARVINAS COM 04335A105 2,283,048 0 0.00 29,337 -23.83 8.0530
2018-11-13 2018-09-30 13F ARVINAS COM 04335A105 2,283,048 2,283,048 38,515 7.0084
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.