Alto Neuroscience, Inc.
US ˙ NYSE

SecurityANRO / Alto Neuroscience, Inc.
InstitutionFranklin Resources Inc
Latest Disclosed Ownership1,101,874 shares
Latest Disclosed Value $ 24,770,128
Franklin Resources Inc reports 1.58% decrease in ownership of ANRO / Alto Neuroscience, Inc.

On May 13, 2026 - Franklin Resources Inc filed a 13F-HR form disclosing ownership of 1,101,874 shares of Alto Neuroscience, Inc. (US:ANRO) valued at $24,770,128 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 11, 2026 disclosing 1,119,578 shares of Alto Neuroscience, Inc.. This represents a change in shares of -1.58% during the quarter. The current value of the position is $20,770,325 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-13 2026-03-31 13F ALTO NEUROSCIENCE COM SHS 02157Q109 1,101,874 -17,704 -1.58 24,770 24.30 0.0010
2026-02-11 2025-12-31 13F ALTO NEUROSCIENCE COM SHS 02157Q109 1,119,578 -43,030 -3.70 19,928 326.45 0.0049
2025-11-13 2025-09-30 13F ALTO NEUROSCIENCE COM SHS 02157Q109 1,162,608 0 0.00 4,674 82.75 0.0012
2025-08-12 2025-06-30 13F ALTO NEUROSCIENCE COM SHS 02157Q109 1,162,608 0 0.00 2,558 1.83 0.0007
2025-05-13 2025-03-31 13F ALTO NEUROSCIENCE COM SHS 02157Q109 1,162,608 0 0.00 2,511 -48.93 0.0007
2025-02-12 2024-12-31 13F ALTO NEUROSCIENCE COM SHS 02157Q109 1,162,608 -58,104 -4.76 4,918 -71.04 0.0014
2024-11-27 2024-09-30 13F/A-1 ALTO NEUROSCIENCE COM SHS 02157Q109 1,220,712 595,673 95.30 16,980 154.15 0.0048
2024-11-12 2024-09-30 13F ALTO NEUROSCIENCE COM SHS 02157Q109 1,220,712 595,673 16,980 0.0008
2024-08-14 2024-06-30 13F ALTO NEUROSCIENCE COM SHS 02157Q109 625,039 27 0.00 6,682 -30.36 0.0021
2024-05-13 2024-03-31 13F ALTO NEUROSCIENCE COM SHS 02157Q109 625,012 625,012 9,594 0.0030
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.