Amylyx Pharmaceuticals, Inc.

SecurityAMLX / Amylyx Pharmaceuticals, Inc.
InstitutionWalleye Capital LLC
Latest Disclosed Ownership61,711 shares
Latest Disclosed Value $ 857,783
Walleye Capital LLC ownership in AMLX / Amylyx Pharmaceuticals, Inc.

On May 13, 2026 - Walleye Capital LLC filed a 13F-HR/A form disclosing ownership of 61,711 shares of Amylyx Pharmaceuticals, Inc. (US:AMLX) valued at $857,783 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 5,740 shares of Amylyx Pharmaceuticals, Inc.. This represents a change in shares of 975.10% during the quarter. The current value of the position is $814,585 USD.

Walleye Capital LLC has a history of taking positions in derivatives of the underlying security (AMLX) in the form of stock options. The firm currently holds call options representing 6,300 of underlying shares valued at $87,570 USD and put options representing 1,800 of underlying shares valued at $25,020 USD .

Note: prior versions of this page mistakenly stated that the share values represented the number of options, not the number of underlying shares. For more information on the data backing these reports, please see the SEC document Frequently Asked Questions About Form 13F.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Institutional Put/Call Ratios
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In addition to reporting standard equity and debt issues, institutions with more than 100MM assets under management must also disclose their put and call option holdings. Since put options generally indicate negative sentiment, and call options indicate positive sentiment, we can get a sense of the overall institutional sentiment by plotting the ratio of puts to calls. The chart to the right plots the historical put/call ratio for this instrument.

Using Put/Call Ratio as an indicator of investor sentiment overcomes one of the key deficiencies of using total institutional ownership, which is that a significant amount of assets under management are invested passively to track indices. Passively-managed funds do not typically buy options, so the put/call ratio indicator more closely tracks the sentiment of actively-managed funds.

AMLX / Amylyx Pharmaceuticals, Inc. Historical Put/Call Ratio
Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-13 2026-03-31 13F/A-1 AMYLYX PHARMACEUTICALS COM 03237H101 61,711 55,971 975.10 858 1,142.03 0.0036
2026-05-08 2026-03-31 13F AMYLYX PHARMACEUTICALS COM 03237H101 61,711 55,971 858 0.0036
2026-02-13 2025-12-31 13F AMYLYX PHARMACEUTICALS COM 03237H101 5,740 5,740 69 0.0002
2025-08-13 2025-06-30 13F AMYLYX PHARMACEUTICALS COM 03237H101 0 -250,888 -100.00 0 -100.00
2025-05-14 2025-03-31 13F AMYLYX PHARMACEUTICALS COM 03237H101 250,888 -267,896 -51.64 888 -54.72 0.0040
2025-02-13 2024-12-31 13F AMYLYX PHARMACEUTICALS COM 03237H101 518,784 -151,810 -22.64 1,961 -9.71 0.0048
2024-11-14 2024-09-30 13F AMYLYX PHARMACEUTICALS COM 03237H101 670,594 608,874 986.51 2,173 1,756.41 0.0045
2024-08-14 2024-06-30 13F AMYLYX PHARMACEUTICALS COM 03237H101 61,720 -300,150 -82.94 117 -88.61 0.0002
2024-05-15 2024-03-31 13F AMYLYX PHARMACEUTICALS COM 03237H101 361,870 -220,858 -37.90 1,028 -88.03 0.0018
2024-02-14 2023-12-31 13F AMYLYX PHARMACEUTICALS COM 03237H101 582,728 481,769 477.19 8,578 364.12 0.0182
2023-11-21 2023-09-30 13F/A-1 AMYLYX PHARMACEUTICALS COM 03237H101 100,959 48,581 92.75 1,849 63.68 0.0047
2023-11-14 2023-09-30 13F AMYLYX PHARMACEUTICALS COM 03237H101 100,959 1,849
2023-08-14 2023-06-30 13F AMYLYX PHARMACEUTICALS COM 03237H101 52,378 52,378 1,130 0.0041
2023-05-15 2023-03-31 13F AMYLYX PHARMACEUTICALS COM 03237H101 0 -17,492 -100.00 0 -100.00
2023-02-14 2022-12-31 13F AMYLYX PHARMACEUTICALS COM 03237H101 17,492 -44,390 -71.73 646 -62.92 0.0118
2022-11-14 2022-09-30 13F AMYLYX PHARMACEUTICALS COM 03237H101 61,882 61,882 1,742 0.0332
2022-08-19 2022-06-30 13F/A-1 AMYLYX PHARMACEUTICALS COM 03237H101 0 -28,187 -100.00 0 -100.00
2022-08-08 2022-06-30 13F AMYLYX PHARMACEUTICALS COM 03237H101 0 0
2022-05-27 2022-03-31 13F/A-01 AMYLYX PHARMACEUTICALS COM 03237H101 28,187 28,187 362 0.0097
2022-05-16 2022-03-31 13F AMYLYX PHARMACEUTICALS COM 03237H101 28,187 362
Disclosed Call Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share
Price
Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2026-05-13 2026-03-31 13F/A AMYLYX PHARMACEUTICALS COM Call 6,300 -80.06 88 -77.17 n/a n/a n/a
2026-05-08 2026-03-31 13F AMYLYX PHARMACEUTICALS COM Call 6,300 88 n/a n/a n/a
2026-02-13 2025-12-31 13F AMYLYX PHARMACEUTICALS COM Call 31,600 42.34 382 26.58 n/a n/a n/a
2025-11-14 2025-09-30 13F AMYLYX PHARMACEUTICALS COM Call 22,200 302 n/a n/a n/a
2025-05-14 2025-03-31 13F AMYLYX PHARMACEUTICALS COM Call 0 -100.00 0 -100.00 n/a n/a n/a
2025-02-13 2024-12-31 13F AMYLYX PHARMACEUTICALS COM Call 23,000 87 n/a n/a n/a
2024-08-14 2024-06-30 13F AMYLYX PHARMACEUTICALS COM Call 0 -100.00 0 -100.00 n/a n/a n/a
2024-05-15 2024-03-31 13F AMYLYX PHARMACEUTICALS COM Call 7,300 -63.32 21 -93.15 n/a n/a n/a
2024-02-14 2023-12-31 13F AMYLYX PHARMACEUTICALS COM Call 19,900 -20.72 293 -36.38 n/a n/a n/a
2023-11-21 2023-09-30 13F/A AMYLYX PHARMACEUTICALS COM Call 25,100 84.56 460 56.66 n/a n/a n/a
2023-11-14 2023-09-30 13F AMYLYX PHARMACEUTICALS COM Call 25,100 460 n/a n/a n/a
2023-08-14 2023-06-30 13F AMYLYX PHARMACEUTICALS COM Call 13,600 293 n/a n/a n/a
2023-05-15 2023-03-31 13F AMYLYX PHARMACEUTICALS COM Call 0 -100.00 0 -100.00 n/a n/a n/a
2023-02-14 2022-12-31 13F AMYLYX PHARMACEUTICALS COM Call 2,900 107 n/a n/a n/a
Disclosed Put Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share Price Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2026-05-13 2026-03-31 13F/A AMYLYX PHARMACEUTICALS COM Put 1,800 -79.78 25 -76.64 n/a n/a n/a
2026-05-08 2026-03-31 13F AMYLYX PHARMACEUTICALS COM Put 1,800 25 n/a n/a n/a
2026-02-13 2025-12-31 13F AMYLYX PHARMACEUTICALS COM Put 8,900 30.88 108 16.30 n/a n/a n/a
2025-11-14 2025-09-30 13F AMYLYX PHARMACEUTICALS COM Put 6,800 92 n/a n/a n/a
2025-05-14 2025-03-31 13F AMYLYX PHARMACEUTICALS COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2025-02-13 2024-12-31 13F AMYLYX PHARMACEUTICALS COM Put 33,500 127 n/a n/a n/a
2024-08-14 2024-06-30 13F AMYLYX PHARMACEUTICALS COM Put 0 -100.00 0 n/a n/a n/a
2024-05-15 2024-03-31 13F AMYLYX PHARMACEUTICALS COM Put 100 0 n/a n/a n/a
2024-02-14 2023-12-31 13F AMYLYX PHARMACEUTICALS COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2023-11-21 2023-09-30 13F/A AMYLYX PHARMACEUTICALS COM Put 1,800 33 n/a n/a n/a
2023-11-14 2023-09-30 13F AMYLYX PHARMACEUTICALS COM Put 1,800 33 n/a n/a n/a
2023-05-15 2023-03-31 13F AMYLYX PHARMACEUTICALS COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2023-02-14 2022-12-31 13F AMYLYX PHARMACEUTICALS COM Put 6,700 248 n/a n/a n/a
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.