Alector, Inc.
US ˙ NasdaqGS ˙ US0144421072

SecurityALEC / Alector, Inc.
InstitutionBarclays Plc
Latest Disclosed Ownership398,687 shares
Latest Disclosed Value $ 621,952
Barclays Plc reports 54.35% decrease in ownership of ALEC / Alector, Inc.

On February 13, 2026 - Barclays Plc filed a 13F-HR form disclosing ownership of 398,687 shares of Alector, Inc. (US:ALEC) valued at $621,952 USD as of December 31, 2025. The entity filed a previous 13F-HR/A on March 31, 2026 disclosing 873,375 shares of Alector, Inc.. This represents a change in shares of -54.35% during the quarter. The current value of the position is $721,623 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-02-13 2025-12-31 13F ALECTOR COM 014442107 398,687 -474,688 -54.35 622 -75.98 0.0001
2026-03-31 2025-09-30 13F/A-3 ALECTOR COM 014442107 873,375 703,580 414.37 2,585 990.72 0.0006
2026-03-19 2025-09-30 13F/A-2 ALECTOR COM 014442107 176,800 7,005 824 0.0002
2025-11-12 2025-09-30 13F ALECTOR COM 014442107 873,375 703,580 2,585 0.0006
2026-02-27 2025-06-30 13F/A-2 ALECTOR COM 014442107 169,795 44,709 35.74 238 54.90 0.0001
2025-08-14 2025-06-30 13F/A-1 ALECTOR COM 014442107 169,795 44,709 0 0.0001
2025-08-13 2025-06-30 13F ALECTOR COM 014442107 169,795 44,709 0 0.0000
2026-03-17 2025-03-31 13F/A-1 ALECTOR COM 014442107 125,086 -51,483 -29.16 154 -54.05 0.0000
2025-05-15 2025-03-31 13F ALECTOR COM 014442107 125,086 -51,483 0 0.0000
2026-03-19 2024-12-31 13F/A-1 ALECTOR COM 014442107 176,569 -231 -0.13 334 -59.54 0.0001
2025-02-13 2024-12-31 13F ALECTOR COM 014442107 176,569 -231 0 0.0001
2026-03-31 2024-09-30 13F/A-2 ALECTOR COM 014442107 176,800 100,731 132.42 824 138.55 0.0002
2024-11-19 2024-09-30 13F/A-1 ALECTOR COM 014442107 176,800 100,731 1 0.0002
2024-11-15 2024-09-30 13F ALECTOR COM 014442107 176,800 100,731 1 0.0001
2026-03-23 2024-06-30 13F/A-1 ALECTOR COM 014442107 76,069 -26,156 -25.59 345 -43.90 0.0001
2024-08-14 2024-06-30 13F ALECTOR COM 014442107 76,069 -26,156 0 0.0001
2026-03-24 2024-03-31 13F/A-1 ALECTOR COM 014442107 102,225 -91,003 -47.10 615 -60.09 0.0002
2024-05-15 2024-03-31 13F ALECTOR COM 014442107 102,225 -91,003 1 0.0002
2026-03-25 2023-12-31 13F/A-1 ALECTOR COM 014442107 193,228 54,402 39.19 1,542 71.41 0.0006
2024-02-15 2023-12-31 13F ALECTOR COM 014442107 193,228 54,402 2 0.0006
2026-03-26 2023-09-30 13F/A-1 ALECTOR COM 014442107 138,826 26,856 23.98 900 33.78 0.0006
2023-11-07 2023-09-30 13F ALECTOR COM 014442107 138,826 26,856 1 0.0006
2026-03-30 2023-06-30 13F/A-2 ALECTOR COM 014442107 111,970 -15,325 -12.04 673 -14.61 0.0004
2023-09-20 2023-06-30 13F/A-1 ALECTOR COM 014442107 111,970 -15,325 1 0.0004
2023-08-03 2023-06-30 13F ALECTOR COM 014442107 111,970 -15,325 1 0.0004
2026-03-30 2023-03-31 13F/A-1 ALECTOR COM 014442107 127,295 -11,446 -8.25 788 -38.52 0.0004
2023-05-04 2023-03-31 13F ALECTOR COM 014442107 127,295 -11,446 1 0.0004
2026-03-30 2022-12-31 13F/A-1 ALECTOR COM 014442107 138,741 -17,867 -11.41 1,281 -13.57 0.0006
2023-02-13 2022-12-31 13F ALECTOR COM 014442107 138,741 -17,867 1 0.0006
2022-11-03 2022-09-30 13F ALECTOR COM 014442107 156,608 137,308 711.44 1,481 655.61 0.0016
2022-08-12 2022-06-30 13F ALECTOR COM 014442107 19,300 737 3.97 196 -26.04 0.0001
2022-05-16 2022-03-31 13F ALECTOR COM 014442107 18,563 -91,358 -83.11 265 -88.32 0.0002
2022-02-23 2021-12-31 13F/A-1 ALECTOR COM 014442107 109,921 36,526 49.77 2,269 35.46 0.0008
2022-02-14 2021-12-31 13F ALECTOR COM 014442107 109,921 36,526 2,269 0.0003
2021-11-09 2021-09-30 13F ALECTOR COM 014442107 73,395 16,182 28.28 1,675 40.52 0.0008
2021-08-13 2021-06-30 13F ALECTOR COM 014442107 57,213 -42,907 -42.86 1,192 -40.90 0.0006
2021-05-13 2021-03-31 13F ALECTOR COM 014442107 100,120 67,520 207.12 2,017 309.13 0.0011
2021-02-11 2020-12-31 13F ALECTOR COM 014442107 32,600 -6,965 -17.60 493 18.23 0.0003
2020-11-12 2020-09-30 13F ALECTOR COM 014442107 39,565 -27,321 -40.85 417 -74.48 0.0002
2020-08-12 2020-06-30 13F ALECTOR COM 014442107 66,886 21,824 48.43 1,634 50.46 0.0013
2020-05-13 2020-03-31 13F ALECTOR COM 014442107 45,062 -4,001 -8.15 1,086 28.37 0.0009
2020-02-10 2019-12-31 13F ALECTOR COM 014442107 49,063 23,466 91.67 846 129.27 0.0005
2019-11-15 2019-09-30 13F/A-1 ALECTOR COM 014442107 25,597 11,431 80.69 369 37.17 0.0002
2019-11-14 2019-09-30 13F ALECTOR COM 014442107 25,597 11,431 369 85.3132
2019-08-14 2019-06-30 13F ALECTOR COM 014442107 14,166 12,596 802.29 269 827.59 0.0002
2019-05-15 2019-03-31 13F ALECTOR COM 014442107 1,570 1,570 29 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.