Agios Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US00847X1046

SecurityAGIO / Agios Pharmaceuticals, Inc.
InstitutionTd Asset Management Inc
Latest Disclosed Ownership23,732 shares
Latest Disclosed Value $ 802,854
Td Asset Management Inc reports 58.58% decrease in ownership of AGIO / Agios Pharmaceuticals, Inc.

On May 11, 2026 - Td Asset Management Inc filed a 13F-HR form disclosing ownership of 23,732 shares of Agios Pharmaceuticals, Inc. (US:AGIO) valued at $802,854 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 10, 2026 disclosing 57,292 shares of Agios Pharmaceuticals, Inc.. This represents a change in shares of -58.58% during the quarter. The current value of the position is $671,378 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-11 2026-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 23,732 -33,560 -58.58 803 -48.56 0.0003
2026-02-10 2025-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 57,292 -71,002 -55.34 1,559 -69.72 0.0013
2025-11-10 2025-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 128,294 -39,900 -23.72 5,150 -7.95 0.0042
2025-07-28 2025-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 168,194 -9,878 -5.55 5,594 7.23 0.0048
2025-05-07 2025-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 178,072 12,400 7.48 5,218 -4.15 0.0048
2025-02-11 2024-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 165,672 -61,600 -27.10 5,444 -47.49 0.0048
2024-11-01 2024-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 227,272 16,800 7.98 10,366 14.21 0.0091
2024-08-02 2024-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 210,472 54,054 34.56 9,076 98.45 0.0085
2024-05-08 2024-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 156,418 64,200 69.62 4,574 122.75 0.0043
2024-02-12 2023-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 92,218 0 0.00 2,054 -10.04 0.0020
2023-10-27 2023-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 92,218 43,719 90.14 2,282 66.21 0.0028
2023-08-09 2023-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 48,499 0 0.00 1,373 23.25 0.0016
2023-05-10 2023-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 48,499 -16,700 -25.61 1,114 -39.13 0.0013
2023-02-07 2022-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 65,199 9,400 16.85 1,831 14.81 0.0023
2022-11-07 2022-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 55,799 -8,900 -13.76 1,594 11.16 0.0020
2022-08-04 2022-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 64,699 -5,956 -8.43 1,434 -30.29 0.0017
2022-05-10 2022-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 70,655 -16,160 -18.61 2,057 -27.93 0.0012
2022-02-10 2021-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 86,815 18,820 27.68 2,854 -9.05 0.0024
2021-11-09 2021-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 67,995 3,800 5.92 3,138 1.65 0.0033
2021-08-11 2021-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 64,195 -1,889 -2.86 3,087 -9.55 0.0031
2021-05-14 2021-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 66,084 7,916 13.61 3,413 35.44 0.0038
2021-02-16 2020-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 58,168 -4,100 -6.58 2,520 15.65 0.0031
2020-11-10 2020-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 62,268 0 0.00 2,179 -34.56 0.0030
2020-08-13 2020-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 62,268 16,800 36.95 3,330 106.45 0.0047
2020-05-15 2020-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 45,468 1,400 3.18 1,613 -23.34 0.0027
2020-02-11 2019-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 44,068 -1,800 -3.92 2,104 41.59 0.0031
2019-11-07 2019-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 45,868 -1,600 -3.37 1,486 -37.25 0.0023
2019-08-01 2019-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 47,468 -5,200 -9.87 2,368 -33.33 0.0035
2019-05-08 2019-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 52,668 11,068 26.61 3,552 85.19 0.0054
2019-02-01 2018-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 41,600 -12,900 -23.67 1,918 -54.37 0.0033
2018-11-01 2018-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 54,500 -1,000 -1.80 4,203 -10.10 0.0062
2018-07-31 2018-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 55,500 -2,900 -4.97 4,675 -2.11 0.0071
2018-05-11 2018-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 58,400 23,557 67.61 4,776 139.76 0.0073
2018-02-02 2017-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 34,843 1,043 3.09 1,992 -11.70 0.0029
2017-11-09 2017-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 33,800 3,800 12.67 2,256 46.11 0.0034
2017-08-01 2017-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 30,000 1,400 4.90 1,544 -7.54 0.0024
2017-05-05 2017-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 28,600 3,300 13.04 1,670 58.14 0.0027
2017-02-08 2016-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 25,300 4,700 22.82 1,056 -2.94 0.0018
2016-11-02 2016-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 20,600 7,400 56.06 1,088 96.75 0.0019
2016-08-04 2016-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 13,200 13,200 0.00 553 0.0010
2016-05-05 2016-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 0 0 0 0.0000
2016-02-04 2015-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 0 -2,900 -100.00 0 -100.00
2015-11-12 2015-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 2,900 0 0.00 205 -36.34 0.0004
2015-08-11 2015-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 2,900 0 0.00 322 17.95 0.0006
2015-04-28 2015-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 2,900 2,900 273 0.0005
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.