Agios Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US00847X1046

SecurityAGIO / Agios Pharmaceuticals, Inc.
InstitutionDimensional Fund Advisors Lp
Latest Disclosed Ownership1,151,614 shares
Latest Disclosed Value $ 38,940,060
Dimensional Fund Advisors Lp reports 14.66% increase in ownership of AGIO / Agios Pharmaceuticals, Inc.

On May 7, 2026 - Dimensional Fund Advisors Lp filed a 13F-HR form disclosing ownership of 1,151,614 shares of Agios Pharmaceuticals, Inc. (US:AGIO) valued at $38,959,102 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 1,004,341 shares of Agios Pharmaceuticals, Inc.. This represents a change in shares of 14.66% during the quarter. The current value of the position is $31,876,676 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-07 2026-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,151,614 147,273 14.66 38,940 42.44 0.0017
2026-02-12 2025-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,004,341 -16,860 -1.65 27,338 -33.30 0.0057
2025-11-12 2025-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,021,201 -84,892 -7.67 40,987 11.41 0.0088
2025-08-12 2025-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,106,093 -155,980 -12.36 36,790 -0.52 0.0085
2025-05-13 2025-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,262,073 -66,992 -5.04 36,981 -15.33 0.0092
2025-02-13 2024-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,329,065 -233,118 -14.92 43,674 -37.08 0.0105
2024-11-07 2024-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,562,183 -633,902 -28.87 69,412 -26.70 0.0168
2024-08-09 2024-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 2,196,085 -382,473 -14.83 94,697 25.60 0.0247
2024-05-10 2024-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 2,578,558 -18,206 -0.70 75,397 30.37 0.0204
2024-02-07 2023-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 2,596,764 137,873 5.61 57,832 -4.97 0.0169
2023-11-09 2023-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 2,458,891 195,073 8.62 60,858 -5.07 0.0200
2023-08-09 2023-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 2,263,818 172,467 8.25 64,109 33.46 0.0204
2023-05-12 2023-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 2,091,351 438,272 26.51 48,037 104,328.26 0.0162
2023-02-09 2022-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,653,079 174,690 11.82 46 -99.89 0.0137
2022-11-10 2022-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,478,389 135,232 10.07 41,811 40.41 0.0161
2022-08-12 2022-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 1,343,157 332,541 32.90 29,778 1.22 0.0107
2022-05-13 2022-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 1,010,616 285,215 39.32 29,420 23.38 0.0091
2022-02-09 2021-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 725,401 184,903 34.21 23,845 -4.41 0.0072
2021-11-12 2021-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 540,498 256,725 90.47 24,944 59.52 0.0080
2021-08-12 2021-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 283,773 -6,433 -2.22 15,637 4.36 0.0050
2021-05-14 2021-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 290,206 -555 -0.19 14,983 18.91 0.0050
2021-03-08 2020-12-31 13F/A-2 AGIOS PHARMACEUTICALS COM 00847X104 290,761 -34,845 -10.70 12,600 10.57 0.0045
2021-02-11 2020-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 290,761 -34,845 12,600 4,550.4503
2020-11-12 2020-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 325,606 -14,920 -4.38 11,395 -37.43 0.0048
2020-08-13 2020-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 340,526 -44,620 -11.59 18,211 33.28 0.0080
2020-05-14 2020-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 385,146 49,471 14.74 13,664 -14.75 0.0071
2020-02-14 2019-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 335,675 78,655 30.60 16,029 92.40 0.0058
2019-11-12 2019-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 257,020 82,860 47.58 8,331 -4.10 0.0032
2019-08-13 2019-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 174,160 -4,727 -2.64 8,687 -27.98 0.0034
2019-08-12 2019-03-31 13F/A-2 AGIOS PHARMACEUTICALS COM 00847X104 178,887 -3,263 -1.79 12,062 43.61 0.0048
2019-05-10 2019-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 178,887 -3,263 12,062
2019-02-26 2018-12-31 13F/A-1 AGIOS PHARMACEUTICALS COM 00847X104 182,150 39,255 27.47 8,399 -23.78 0.0038
2019-02-13 2018-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 182,150 39,255 8,399
2018-11-13 2018-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 142,895 42,200 41.91 11,019 29.94 0.0042
2018-08-10 2018-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 100,695 24,051 31.38 8,480 35.29 0.0034
2018-05-11 2018-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 76,644 76,644 6,268 0.0026
2016-02-10 2015-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 0 -50,137 -100.00 0 -100.00
2015-11-13 2015-09-30 13F AGIOS PHARMACEUTICALS COM 00847X104 50,137 -3,377 -6.31 3,538 -40.48 0.0023
2015-08-14 2015-06-30 13F AGIOS PHARMACEUTICALS COM 00847X104 53,514 7,185 15.51 5,944 36.02 0.0036
2015-05-14 2015-03-31 13F AGIOS PHARMACEUTICALS COM 00847X104 46,329 9,555 25.98 4,370 6.07 0.0028
2015-02-06 2014-12-31 13F AGIOS PHARMACEUTICALS COM 00847X104 36,774 36,774 4,120 0.0027
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.