Rhythm Pharmaceuticals, Inc.
MX ˙ BMV ˙ US76243J1051
SecurityMX:RYTM / Rhythm Pharmaceuticals, Inc.
InstitutionUbs Asset Management Americas Inc
Latest Disclosed Ownership541,450 shares
Latest Disclosed Value $ 47,089,907
Ubs Asset Management Americas Inc reports 1.38% decrease in ownership of RYTM / Rhythm Pharmaceuticals, Inc.

On May 13, 2026 - Ubs Asset Management Americas Inc filed a 13F-HR form disclosing ownership of 541,450 shares of Rhythm Pharmaceuticals, Inc. (MX:RYTM) valued at $47,089,907 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 549,020 shares of Rhythm Pharmaceuticals, Inc.. This represents a change in shares of -1.38% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-13 2026-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 541,450 -7,570 -1.38 47,090 -19.87 0.0015
2026-02-13 2025-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 549,020 111,548 25.50 58,767 33.02 0.0124
2025-11-14 2025-09-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 437,472 209,845 92.19 44,180 207.17 0.0096
2025-08-14 2025-06-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 227,627 101,845 80.97 14,384 115.90 0.0029
2025-05-19 2025-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 125,782 -92,762 -42.45 6,663 -45.55 0.0017
2025-02-14 2024-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 218,544 -6,829 -3.03 12,234 3.62 0.0029
2024-11-14 2024-09-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 225,373 -11,058 -4.68 11,807 21.63 0.0030
2024-08-14 2024-06-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 236,431 29,451 14.23 9,708 8.24 0.0028
2024-05-15 2024-03-31 13F RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 206,980 -2,958 -1.41 8,968 -7.07 0.0032
2024-02-14 2023-12-31 13F RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 209,938 -127,326 -37.75 9,651 24.82 0.0038
2023-11-13 2023-09-30 13F RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 337,264 131,229 63.69 7,732 110.37 0.0035
2023-08-11 2023-06-30 13F RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 206,035 0 0.00 3,676 0.00 0.0018
2023-05-15 2023-03-31 13F RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 206,035 163,838 388.27 3,676 199.27 0.0018
2023-02-14 2022-12-31 13F RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 42,197 12,260 40.95 1,229 67.53 0.0006
2022-11-14 2022-09-30 13F RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 29,937 -24,886 -45.39 733 222.91 0.0004
2022-08-12 2022-06-30 13F RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 54,823 25,392 86.28 228 -33.04 0.0001
2022-05-16 2022-03-31 13F RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 29,431 0 0.00 339 15.70 0.0001
2022-02-14 2021-12-31 13F RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 29,431 4,216 16.72 294 -10.94 0.0001
2021-11-15 2021-09-30 13F RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 25,215 0 0.00 329 -33.27 0.0001
2021-08-16 2021-06-30 13F RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 25,215 14,719 140.23 494 121.08 0.0002
2021-05-14 2021-03-31 13F RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 10,496 -18,630 -63.96 223 -74.22 0.0001
2021-03-01 2020-12-31 13F/A-1 RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 29,126 -2,838 -8.88 866 25.00 0.0004
2021-02-17 2020-12-31 13F RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 31,964 0 693 0.0653
2020-11-13 2020-09-30 13F RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 31,964 12,901 67.68 693 62.82 0.0004
2020-08-14 2020-06-30 13F RHYTHM PHARMACEUTICALS EQUITY US CM 76243J105 19,063 19,063 425 0.0003
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.